3D‐printed blood vessels engineered to more closely mimic human vasculature DOI
Aakash Shah

Artificial Organs, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Summary Novel bioprinting technique offers strategy for building dense organ systems with complex multilayered vascular networks. Building on a called “sacrificial writing in functional tissue,” researchers have developed immature capable of maintaining rudimentary function and viability owing to an intricate network.

Language: Английский

Integrating Microfluidics, Hydrogels, and 3D Bioprinting for Personalized Vessel-on-a-Chip Platforms DOI
San Seint Seint Aye, Zhi Fang, Mike C. L. Wu

et al.

Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Advancement of vascular models from simple 2D culture to complex vessel-on-a-chip platforms through integration microfluidics, biomimetic hydrogels, and 3D bioprinting, enabling controlled investigation thrombosis mechanisms.

Language: Английский

Citations

1

Process Optimization for Coaxial Extrusion-Based Bioprinting: A Comprehensive Analysis of Material Behavior, Structural Precision, and Cell Viability DOI

Jiarun Sun,

Youping Gong,

Yuchen He

et al.

Additive manufacturing, Journal Year: 2025, Volume and Issue: unknown, P. 104682 - 104682

Published: Jan. 1, 2025

Language: Английский

Citations

1

Vascularization of Organoid Microenvironments: Perfusable Networks for Organoid Growth and Maturation DOI Creative Commons
Marc Vila Cuenca, Merve Bulut, Christine L. Mummery

et al.

Current Opinion in Biomedical Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 100586 - 100586

Published: March 1, 2025

Language: Английский

Citations

0

Scaffold Internal Network Bioprinting for Vascularized Tissue Regeneration DOI

Lai Suo,

Yaqi Guo,

Shan Mou

et al.

Composites Part B Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 112401 - 112401

Published: March 1, 2025

Language: Английский

Citations

0

Biomechanical and mechanobiological design for bioprinting functional microvasculature DOI
Dongrui Zhang, J. Liu, Xiao Liu

et al.

Applied Physics Reviews, Journal Year: 2025, Volume and Issue: 12(1)

Published: March 1, 2025

Functional microvasculature is essential for in vitro tissue constructs, ensuring efficient transport of oxygen, nutrients, and waste supporting vital paracrine signaling stability. Recent advancements both direct indirect 3D bioprinting offer promising solutions to construct complex vascular networks by allowing precise control over cell extracellular matrix placement. The process from shape printing function formation involves dynamic shift bioink mechanical properties, microenvironments, mechanobiology endothelial cells. This review explores how biomechanical mechanobiological principles are integrated into the develop functional microvascular networks. Before printing, a top-level design approach based on these focuses interactions among biomaterials, behaviors, environments guide network fabrication. During bioinks different techniques, along with optimized factors process, ensures accurate structure reproduction while maintaining viability. After emphasis creating suitable environment modulate multiple steps neovascularization, including initiation, morphogenesis, lumen formation, stabilization, maturation microvasculature. Finally, we discuss future developments drive functionalized

Language: Английский

Citations

0

Hydrogel-Based Bioinks for Coaxial and Triaxial Bioprinting: A Review of Material Properties, Printing Techniques, and Applications DOI Open Access
Alma Tamunonengiofori Banigo,

Laura Nauta,

Bram Zoetebier

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 917 - 917

Published: March 28, 2025

Three-dimensional bioprinting technology has emerged as a rapidly advancing multidisciplinary field with significant potential for tissue engineering applications. This enables the formation of complex tissues and organs by utilizing hydrogels, or without cells, scaffolds structural supports. Among various methods, advanced using coaxial triaxial nozzles stands out promising technique. Coaxial technique simultaneously deposits two material streams through nozzle, enabling controlled an outer shell inner core construct. In contrast, utilizes three namely shell, to fabricate more constructs. Despite growing interest in 3D bioprinting, development suitable cell-laden bioinks creating remains unclear. To address this gap, systematic review was conducted preferred reporting items reviews meta-analyses (PRISMA) flowchart, collecting 1621 papers from databases, including Web Science, PUBMED, SCOPUS, Springer Link. After careful selection, 85 research articles focusing on were included review. Specifically, 77 concentrated 11 focused 3 covering both techniques. The search, between 1 April 30 September 2023, had no restrictions publication date, carried due heterogeneity studies. primary objective is assess identify most commonly occurring critical successful advancements technologies. focuses delineating explored utilized approaches. It evaluating inherent merits these bioinks, systematically comparing them while emphasizing their classifications, essential attributes, properties, limitations within domain engineering. Additionally, considers applications offering comprehensive insights into efficacy utility technology. Overall, provides overview some conditions relevant hydrogel used Future directions aimed at are also briefly discussed.

Language: Английский

Citations

0

Construction strategies for 3D printed cardiac tissue repair materials and their application potential DOI Creative Commons

Mingru Kong,

Zhenguo Wu, Zhifang Zheng

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 19, 2025

Abstract As a major cause of death worldwide, heart disease has significant limitations in traditional treatments. However, 3D printing technology, with its personalized, precise, and multifunctional features, provides new idea for developing cardiac tissue repair materials. This review analyzes the three core advantages technology materials: realization personalized medicine, intelligent construction complex structures, optimization functions multi‐material combinations. Combined specific research cases, this reveals progress valve replacement, patches, vascular stent manufacturing, composite material development, especially potential carbon‐based conductive materials, biomass‐based bio‐based materials repair. In addition, discusses innovative applications advanced technologies design prosthetic including coaxial printing, microfluidic extrusion stereospecific rapid prototyping, two‐photon printing. Finally, summarizes proposes future directions. It emphasizes importance combining study engineering to further improve performance effectiveness Meanwhile, potentials single‐cell spatial genomics, protein prediction optimizing biocompatibility functionality are envisioned provide scientific support more efficient through precise regulation cell behavior, remodeling microenvironment, development

Language: Английский

Citations

0

Organoid bioprinting: from cells to functional tissues DOI
Michelle S. Huang, Fotis Christakopoulos, Julien G. Roth

et al.

Nature Reviews Bioengineering, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

Language: Английский

Citations

2

Engineering the 3D structure of organoids DOI Creative Commons
Steven F. Moss, Ezgi Bakırcı, Adam W. Feinberg

et al.

Stem Cell Reports, Journal Year: 2024, Volume and Issue: unknown, P. 102379 - 102379

Published: Dec. 1, 2024

Language: Английский

Citations

2

3D‐printed blood vessels engineered to more closely mimic human vasculature DOI
Aakash Shah

Artificial Organs, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Summary Novel bioprinting technique offers strategy for building dense organ systems with complex multilayered vascular networks. Building on a called “sacrificial writing in functional tissue,” researchers have developed immature capable of maintaining rudimentary function and viability owing to an intricate network.

Language: Английский

Citations

1