Integrating Microfluidics, Hydrogels, and 3D Bioprinting for Personalized Vessel-on-a-Chip Platforms
Biomaterials Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Advancement
of
vascular
models
from
simple
2D
culture
to
complex
vessel-on-a-chip
platforms
through
integration
microfluidics,
biomimetic
hydrogels,
and
3D
bioprinting,
enabling
controlled
investigation
thrombosis
mechanisms.
Language: Английский
Process Optimization for Coaxial Extrusion-Based Bioprinting: A Comprehensive Analysis of Material Behavior, Structural Precision, and Cell Viability
Jiarun Sun,
No information about this author
Youping Gong,
No information about this author
Yuchen He
No information about this author
et al.
Additive manufacturing,
Journal Year:
2025,
Volume and Issue:
unknown, P. 104682 - 104682
Published: Jan. 1, 2025
Language: Английский
Vascularization of Organoid Microenvironments: Perfusable Networks for Organoid Growth and Maturation
Current Opinion in Biomedical Engineering,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100586 - 100586
Published: March 1, 2025
Language: Английский
Scaffold Internal Network Bioprinting for Vascularized Tissue Regeneration
Lai Suo,
No information about this author
Yaqi Guo,
No information about this author
Shan Mou
No information about this author
et al.
Composites Part B Engineering,
Journal Year:
2025,
Volume and Issue:
unknown, P. 112401 - 112401
Published: March 1, 2025
Language: Английский
Biomechanical and mechanobiological design for bioprinting functional microvasculature
Applied Physics Reviews,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: March 1, 2025
Functional
microvasculature
is
essential
for
in
vitro
tissue
constructs,
ensuring
efficient
transport
of
oxygen,
nutrients,
and
waste
supporting
vital
paracrine
signaling
stability.
Recent
advancements
both
direct
indirect
3D
bioprinting
offer
promising
solutions
to
construct
complex
vascular
networks
by
allowing
precise
control
over
cell
extracellular
matrix
placement.
The
process
from
shape
printing
function
formation
involves
dynamic
shift
bioink
mechanical
properties,
microenvironments,
mechanobiology
endothelial
cells.
This
review
explores
how
biomechanical
mechanobiological
principles
are
integrated
into
the
develop
functional
microvascular
networks.
Before
printing,
a
top-level
design
approach
based
on
these
focuses
interactions
among
biomaterials,
behaviors,
environments
guide
network
fabrication.
During
bioinks
different
techniques,
along
with
optimized
factors
process,
ensures
accurate
structure
reproduction
while
maintaining
viability.
After
emphasis
creating
suitable
environment
modulate
multiple
steps
neovascularization,
including
initiation,
morphogenesis,
lumen
formation,
stabilization,
maturation
microvasculature.
Finally,
we
discuss
future
developments
drive
functionalized
Language: Английский
Hydrogel-Based Bioinks for Coaxial and Triaxial Bioprinting: A Review of Material Properties, Printing Techniques, and Applications
Polymers,
Journal Year:
2025,
Volume and Issue:
17(7), P. 917 - 917
Published: March 28, 2025
Three-dimensional
bioprinting
technology
has
emerged
as
a
rapidly
advancing
multidisciplinary
field
with
significant
potential
for
tissue
engineering
applications.
This
enables
the
formation
of
complex
tissues
and
organs
by
utilizing
hydrogels,
or
without
cells,
scaffolds
structural
supports.
Among
various
methods,
advanced
using
coaxial
triaxial
nozzles
stands
out
promising
technique.
Coaxial
technique
simultaneously
deposits
two
material
streams
through
nozzle,
enabling
controlled
an
outer
shell
inner
core
construct.
In
contrast,
utilizes
three
namely
shell,
to
fabricate
more
constructs.
Despite
growing
interest
in
3D
bioprinting,
development
suitable
cell-laden
bioinks
creating
remains
unclear.
To
address
this
gap,
systematic
review
was
conducted
preferred
reporting
items
reviews
meta-analyses
(PRISMA)
flowchart,
collecting
1621
papers
from
databases,
including
Web
Science,
PUBMED,
SCOPUS,
Springer
Link.
After
careful
selection,
85
research
articles
focusing
on
were
included
review.
Specifically,
77
concentrated
11
focused
3
covering
both
techniques.
The
search,
between
1
April
30
September
2023,
had
no
restrictions
publication
date,
carried
due
heterogeneity
studies.
primary
objective
is
assess
identify
most
commonly
occurring
critical
successful
advancements
technologies.
focuses
delineating
explored
utilized
approaches.
It
evaluating
inherent
merits
these
bioinks,
systematically
comparing
them
while
emphasizing
their
classifications,
essential
attributes,
properties,
limitations
within
domain
engineering.
Additionally,
considers
applications
offering
comprehensive
insights
into
efficacy
utility
technology.
Overall,
provides
overview
some
conditions
relevant
hydrogel
used
Future
directions
aimed
at
are
also
briefly
discussed.
Language: Английский
Construction strategies for 3D printed cardiac tissue repair materials and their application potential
Mingru Kong,
No information about this author
Zhenguo Wu,
No information about this author
Zhifang Zheng
No information about this author
et al.
Deleted Journal,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 19, 2025
Abstract
As
a
major
cause
of
death
worldwide,
heart
disease
has
significant
limitations
in
traditional
treatments.
However,
3D
printing
technology,
with
its
personalized,
precise,
and
multifunctional
features,
provides
new
idea
for
developing
cardiac
tissue
repair
materials.
This
review
analyzes
the
three
core
advantages
technology
materials:
realization
personalized
medicine,
intelligent
construction
complex
structures,
optimization
functions
multi‐material
combinations.
Combined
specific
research
cases,
this
reveals
progress
valve
replacement,
patches,
vascular
stent
manufacturing,
composite
material
development,
especially
potential
carbon‐based
conductive
materials,
biomass‐based
bio‐based
materials
repair.
In
addition,
discusses
innovative
applications
advanced
technologies
design
prosthetic
including
coaxial
printing,
microfluidic
extrusion
stereospecific
rapid
prototyping,
two‐photon
printing.
Finally,
summarizes
proposes
future
directions.
It
emphasizes
importance
combining
study
engineering
to
further
improve
performance
effectiveness
Meanwhile,
potentials
single‐cell
spatial
genomics,
protein
prediction
optimizing
biocompatibility
functionality
are
envisioned
provide
scientific
support
more
efficient
through
precise
regulation
cell
behavior,
remodeling
microenvironment,
development
Language: Английский
Organoid bioprinting: from cells to functional tissues
Nature Reviews Bioengineering,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 16, 2024
Language: Английский
Engineering the 3D structure of organoids
Stem Cell Reports,
Journal Year:
2024,
Volume and Issue:
unknown, P. 102379 - 102379
Published: Dec. 1, 2024
Language: Английский
3D‐printed blood vessels engineered to more closely mimic human vasculature
Artificial Organs,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 13, 2024
Summary
Novel
bioprinting
technique
offers
strategy
for
building
dense
organ
systems
with
complex
multilayered
vascular
networks.
Building
on
a
called
“sacrificial
writing
in
functional
tissue,”
researchers
have
developed
immature
capable
of
maintaining
rudimentary
function
and
viability
owing
to
an
intricate
network.
Language: Английский