Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 30, 2025
Abstract
Functional
biomaterials
composed
of
multiple
biomacromolecules
have
significant
advantages
over
those
made
from
a
single
type.
However,
harmoniously
integrating
various
remains
challenging.
Neutrophil
extracellular
traps
(NETs),
an
emerging
biological
structure
released
neutrophils,
serve
as
natural
prototype
worth
investigating
and
learning
from.
NETs
consist
intricate
exhibit
web‐like
microstructure,
endowing
them
with
multifaceted
roles
in
both
physiological
pathological
processes.
In
this
review,
research
progress
is
systematically
examined
on
materials
science
perspective.
First,
the
origin
transformation
are
introduced,
their
functional
mechanisms
NET
components
thoroughly
dissected
rather
than
conventionally
treating
entity.
Second,
given
complex
functions,
revealed
potential
biomarker
for
disease
prediction.
Third,
typical
characterization
technologies
analysis
summarized.
Fourth,
artificial
inspired
by
discussed.
addition,
regulatory
processes
provide
bio‐inspired
prototypes
design
advanced
materials.
Finally,
perspectives
opportunities
challenges
advancing
presented
biomarkers
models
development
International Materials Reviews,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 13, 2025
In
recent
years,
zwitterionic
materials
have
been
widely
used
in
biomedical
and
nanomedical
due
to
their
unique
structure
which
the
molecule
is
electrically
neutral
with
equal
positive
negative
charge.
This
kind
of
material
could
form
a
thick
hydration
layer
by
electrostatic
effect,
prevent
contamination,
show
wide
applications
life
science
fields,
such
as
resisting
non-specific
protein
adsorption,
biofilm,
thrombosis
formation,
so
on.
Most
importantly,
diversity
functional
groups
has
made
it
more
convenient
for
surface
modification
further
utilization,
creating
multifunctional
various
applications.
review
summarized
up-to-date
materials,
including
conventional
novel
structural
characteristics,
well
blood-contacting
implantable
devices,
antibacterial
coatings,
wound
dressings,
drug-targeted
carriers,
smart
wearable
biosensors,
especially
clinical
uses.
New
discoveries,
existing
challenges,
commercial
status
are
also
outlined,
future
opportunities
development
perspectives
new
biomaterials
demonstrated.
Biomedicines,
Journal Year:
2024,
Volume and Issue:
12(11), P. 2538 - 2538
Published: Nov. 7, 2024
Diabetes
mellitus
is
an
increasingly
prevalent
chronic
metabolic
disorder
characterized
by
physiologic
hyperglycemia
that,
when
left
uncontrolled,
can
lead
to
significant
complications
in
multiple
organs.
Diabetic
wounds
are
common
the
general
population,
yet
underlying
mechanism
of
impaired
healing
such
remains
unclear.
Single-cell
RNA-sequencing
(scRNAseq)
has
recently
emerged
as
a
tool
study
gene
expression
heterogeneous
cell
populations
skin
wounds.
Herein,
we
review
history
scRNAseq
and
its
application
diabetic
wound
healing,
focusing
on
how
innovations
single-cell
sequencing
have
transformed
strategies
for
fibroblast
analysis.
We
summarize
recent
research
role
fibroblasts
describe
functional
cellular
heterogeneity
fibroblasts.
Moreover,
highlight
future
opportunities
research,
with
focus
characterizing
distinct
subpopulations
their
lineages.
Leveraging
technologies
explore
complex
biology
may
reveal
new
therapeutic
targets
improving
ultimately
alleviate
clinical
burden
