Dynamic Electromechanical Co‐Stimulation Based Enhancement of Skeletal Muscle Tissues for Fast Biosyncretic Robots Actuation DOI
Lianchao Yang, Chuang Zhang, Ruiqian Wang

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 35(2)

Published: Oct. 14, 2024

Abstract Biosyncretic robots composed of living and synthetic materials have garnered significant attention due to their high energy conversion efficiency, good biocompatibility human‐robot interaction safety. Among common actuation materials, artificial skeletal muscle tissue (ASMT) stands out for its size scalability, controllability, potential driving force. However, the low differentiation efficiency myoblasts, performance ASMT lags behind that natural tissue, thereby hindering progress biosyncretic robots. Here, inspired by training mode human muscle, an electromechanical co‐stimulation system enhancing ASMTs is proposed. This capable simultaneously applying electrical mechanical stimulation ASMTs. Moreover, resistance can be dynamically adjusted during growth based on real‐time measurements contractile force ASMT. The results show enhanced demonstrate improved actuate a robot at maximum speed 2.38 mm s −1 , which faster than those most currently reported ASMT‐based study introduces novel approach ASMTs, with substantial implications fields engineering.

Language: Английский

Bio‐Integrated Microrobots: Fabrication, Actuation and Biomedical Applications DOI Creative Commons
Huaping Wang, Jiaxin Liu, Ru‐xin Nie

et al.

Published: March 13, 2025

ABSTRACT Bio‐integrated microrobots (BIMs), which are fabricated with biofriendly materials, biological units (e.g. cells or biomolecules), cell‐material hybrids have emerged as a promising technology for minimally invasive biomedicine. The diminutive size and flexible structures enable BIMs to navigate within narrow, deep, challenging‐to‐reach in vivo regions, performing biopsy, diagnostic, drug delivery, therapeutic functions minimal invasiveness. However, the clinical deployment of is highly orchestrated task that requires consideration material properties, structural design, locomotion, observation, outcomes, side effects on tissues, etc. In this review, we review discuss latest advances bio‐integrated microrobot domain, evaluating various methods associated fabrication, actuation, implementation biomedical BIMs. By comparing advantages shortcomings these techniques, highlights challenges future trends intelligent microrobots, huge potential

Language: Английский

Citations

1
Biosyncretic robotic systems: Comprehensive construction, application, and future challenges DOI

Qi Zhang,

Chuang Zhang, Lianchao Yang

et al.

Science China Technological Sciences, Journal Year: 2025, Volume and Issue: 68(4)

Published: March 14, 2025

Language: Английский

Citations

0
Modular Living Muscle‐Based Biomimetic Actuators for Biosyncretic Robots DOI Creative Commons
Lianchao Yang, Chuang Zhang, H. Qin

et al.

Published: April 10, 2025

ABSTRACT Biosyncretic robots that integrate living materials present unique advantages for advancing robotic research. Compared with traditional robots, biosyncretic offer potential benefits such as higher energy efficiency and enhanced biocompatibility. Among various bioactuators, skeletal muscle tissue (SMT) is particularly favored its scalability, to generate high driving forces, controllable on/off actuation. However, current SMT actuators often face challenges, including a limited force suboptimal practical designs, which may impede the development of robots. To address these limitations, this work proposes method fabricating modular actuators. By leveraging biomimetic design structural optimization, contractile performance significantly improved. The achieved maximum 2.92 ± 0.07 mN, demonstrated approximately 28% strain under unloaded conditions, notably exhibited responsive single‐twitch contractions electrical stimulation frequencies up 10 Hz. This response outperforms most existing robot studies. In addition, highly adaptable can be easily assembled construct human‐like actuators, convergent, parallel, bipennate muscles. integrating rigid‐flexible coupled nonliving structures, SMT‐driven caterpillar, dolphin, manta ray have been successfully developed. research presents an innovative approach constructing large, high‐performance, multifunctional contributing advancements in both (or biohybrid robots) engineering.

Language: Английский

Citations

0
Clinical Translation of Inorganic Nanoparticles and Engineered Living Materials for Cancer Therapy DOI
Lucía Gandarias, Damien Faivre

ChemPlusChem, Journal Year: 2024, Volume and Issue: unknown

Published: June 11, 2024

A wide range of particle-based nano- to microsystems is currently under investigation for potential use in personalized nanomedicine. However, only a small fraction these innovations likely make it clinical use. In this concept article, we start by discussing the applications inorganic nanoparticles cancer treatment and diagnosis, shed light on challenges they must overcome become clinically available. second part, focus engineered living materials, which have begun revolutionize way medical interventions could be performed. Finally, share our insights opinions explain why, despite significant advancements research technologies, their translation practice remains limited.

Language: Английский

Citations

2
Dynamic Electromechanical Co‐Stimulation Based Enhancement of Skeletal Muscle Tissues for Fast Biosyncretic Robots Actuation DOI
Lianchao Yang, Chuang Zhang, Ruiqian Wang

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 35(2)

Published: Oct. 14, 2024

Abstract Biosyncretic robots composed of living and synthetic materials have garnered significant attention due to their high energy conversion efficiency, good biocompatibility human‐robot interaction safety. Among common actuation materials, artificial skeletal muscle tissue (ASMT) stands out for its size scalability, controllability, potential driving force. However, the low differentiation efficiency myoblasts, performance ASMT lags behind that natural tissue, thereby hindering progress biosyncretic robots. Here, inspired by training mode human muscle, an electromechanical co‐stimulation system enhancing ASMTs is proposed. This capable simultaneously applying electrical mechanical stimulation ASMTs. Moreover, resistance can be dynamically adjusted during growth based on real‐time measurements contractile force ASMT. The results show enhanced demonstrate improved actuate a robot at maximum speed 2.38 mm s −1 , which faster than those most currently reported ASMT‐based study introduces novel approach ASMTs, with substantial implications fields engineering.

Language: Английский

Citations

1