The Chemical Record,
Journal Year:
2024,
Volume and Issue:
24(7)
Published: July 1, 2024
Abstract
Diorganyl
diselenides
have
emerged
as
privileged
structures
because
they
are
easy
to
prepare,
distinct
reactivity,
and
broad
biological
activity.
They
also
been
used
in
the
synthesis
of
natural
products
an
electrophile
organoselenylation
aromatic
systems
peptides,
reductions
alkenes,
nucleophilic
substitution.
This
review
summarizes
advancements
methods
for
transformations
promoted
by
diorganyl
main
functions
organic
chemistry.
Parallel,
it
will
describe
findings
on
pharmacology
toxicology
diselenides,
emphasizing
anti‐inflammatory,
hypoglycemic,
chemotherapeutic,
antimicrobial
activities.
Therefore,
examination
detailing
reactivity
characteristics
provides
valuable
insights
academic
researchers
industrial
professionals.
Synthesis,
Journal Year:
2024,
Volume and Issue:
56(17), P. 2695 - 2702
Published: June 24, 2024
Abstract
A
straightforward
and
efficient
electrochemical
method
for
the
anodic
oxidative
selenenylation
of
2-(2-arylallyl)phenols
a
2-(3-arylbut-3-en-1-yl)phenol
with
diselenides
under
ambient
air
conditions
has
been
outlined.
This
allows
synthesis
selenyl-dihydrobenzofurans
chromane
featuring
sterically
hindered
tetrasubstituted
carbon
center,
demonstrated
through
25
examples
yields
reaching
up
to
98%.
Initial
mechanistic
investigations
suggest
likely
participation
pivotal
seleniranium
cation
species
in
regulating
reactivity.
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(19), P. 10240 - 10246
Published: Jan. 1, 2024
Herein,
we
report
a
general
and
sustainable
electrochemically
promoted
oxidative
selenocyclization
protocol
for
the
synthesis
of
organoselenyl
isoxazoles
from
2-alkyn-1-one
O
-methyloximes
diorganyl
diselenides.
New Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
48(21), P. 9480 - 9485
Published: Jan. 1, 2024
A
one-pot
strategy
has
been
developed
for
the
synthesis
of
3-selenylated
pyrazolo[1,5-
a
]pyrimidines
from
amino
pyrazoles,
chalcones/enaminones,
and
diselenides
through
I
2
-catalyzed
tandem
cascade
annulations/C–H
selenylation.
Asian Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
12(12)
Published: Oct. 12, 2023
Abstract
A
selenium‐catalyzed
electrophilic
cascade
reaction
of
vinylarenes
with
N
‐fluorobenzenesulfonimide
for
the
efficient
synthesis
important
β‐keto
sulfones
via
a
single
operation
is
developed.
The
reactions
bearing
electron‐withdrawing
groups
and
electron‐donating
proceeded
smoothly
in
air
gave
products
up
to
94
%
yield.
Mechanistic
studies
suggest
that
vinyl
amines
generated
by
oxidative
amination
are
intermediates,
cleavage
N−S
bond
recombination
sulfonyl
radical
lead
1,3‐migration
sulfonyl,
hydrolysis
affords
sulfones.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
366(2), P. 188 - 193
Published: Dec. 1, 2023
Abstract
A
direct
electrosynthesis
of
cyclic
isoureas
from
N
‐allyl
ureas
and
diselenides
has
been
described.
This
protocol
proceeds
without
any
additional
catalyst
oxidant,
at
room
temperature
under
air,
providing
the
desired
products
in
71–91%
yield.
In
addition,
synthesis
containing
five
to
seven‐membered
rings
also
achieved
by
employment
this
strategy.
On
basis
mechanism
experiments
previous
research
works,
a
probable
is
proposed.
The Chemical Record,
Journal Year:
2024,
Volume and Issue:
24(7)
Published: July 1, 2024
Abstract
Diorganyl
diselenides
have
emerged
as
privileged
structures
because
they
are
easy
to
prepare,
distinct
reactivity,
and
broad
biological
activity.
They
also
been
used
in
the
synthesis
of
natural
products
an
electrophile
organoselenylation
aromatic
systems
peptides,
reductions
alkenes,
nucleophilic
substitution.
This
review
summarizes
advancements
methods
for
transformations
promoted
by
diorganyl
main
functions
organic
chemistry.
Parallel,
it
will
describe
findings
on
pharmacology
toxicology
diselenides,
emphasizing
anti‐inflammatory,
hypoglycemic,
chemotherapeutic,
antimicrobial
activities.
Therefore,
examination
detailing
reactivity
characteristics
provides
valuable
insights
academic
researchers
industrial
professionals.
