Directed Regioselective Arylation of Imidazo[1,2-a]pyridine-3-carboxamides using Rh(III) catalysis. DOI
Kousar Jahan,

M. SOOD,

Osheen Jain

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(35), P. 7121 - 7127

Published: Jan. 1, 2024

We introduced, for the first time, N -methoxyamide directed proximal C–H bond activation of imidazo[1,2- a ]pyridines C(sp 2 )–C(sp ) formation via transition metal catalysed approach to obtain C-5 arylated ]pyridines.

Language: Английский

The influence of acid additive on linear and branch selectivity in the C−H alkylation of the N-pyridinecarbonyl protected 2-methylbenzylamine with 1-heptene catalyzed by Rh2(OAc)4: a theoretical investigation DOI

Lingli Han,

Fei Guan,

Zifan Chen

et al.

Organic Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The role of an acid additive and the origins reaction are clarified through our calculations.

Language: Английский

Citations

0
Rh(iii)-catalyzed oxidative [4+2] annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols DOI

Dhananjay S. Nipate,

Neha Meena,

Prakash N. Swami

et al.

Chemical Communications, Journal Year: 2023, Volume and Issue: 60(3), P. 344 - 347

Published: Nov. 28, 2023

Synthesis of functionalized benzo[ a ]phenazines and indazolo[2,3- ]quinolines has been developed through Rh( iii )-catalyzed oxidative annulation 2-aryl-2 H -indazoles 2-arylquinoxalines with allyl alcohols, respectively.

Language: Английский

Citations

7
Microwave‐assisted Rhodium(I)‐Catalyzed C8‐Regioselective C−H Alkenylation and Arylation of 1,2,3,4‐Tetrahydroquinolines with Alkenyl and Aryl Carboxylic Acids DOI Creative Commons
Haoqiang Zhao,

Qi Zeng,

Ji Yang

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(8), P. 1820 - 1826

Published: Feb. 7, 2024

Abstract Rh(I)‐catalyzed C8‐selective C−H alkenylation and arylation of 1,2,3,4‐tetrahydroquinolines with alkenyl aryl carboxylic acids under microwave assistance have been realized. Using [Rh(CO) 2 (acac)] as the catalyst Piv O acid activator, undergo decarbonylative a wide range acids, affording C8‐alkenylated or arylated 1,2,3,4‐tetrahydroquinolines. This method enables synthesis that would otherwise be difficult to access by means conventional protocols. Moreover, this catalytic system also works well in acids. The activity strongly depends on choice N ‐directing group, readily installable removable ‐(2‐pyrimidyl) group being optimal. pathway is elucidated mechanistic experiments.

Language: Английский

Citations

1
Rhodium-Catalyzed Alkylation of Aromatic Ketones with Allylic Alcohols and α,β-Unsaturated Ketones DOI Open Access

Wan-Di Li,

Jiashuo Zhang,

Linyan Zhang

et al.

Catalysts, Journal Year: 2023, Volume and Issue: 13(8), P. 1157 - 1157

Published: July 26, 2023

The direct transition-metal-catalyzed addition of C–H bonds to unsaturated C=X (X=C, O, and N) via bond activation has been recognized as a powerful tool for the construction C–C (in terms atom step economy). Herein, rhodium-catalyzed aromatic ketones allylic alcohols α,β-unsaturated that affords β-aryl carbonyl compounds is described, in which ketone acts weakly coordinating directing group. It was found type alkyl crucial success reaction. This transformation provides convenient efficient methodology synthesis 2-alkyl moderate-to-excellent yields.

Language: Английский

Citations

2
Directed Regioselective Arylation of Imidazo[1,2-a]pyridine-3-carboxamides using Rh(III) catalysis. DOI
Kousar Jahan,

M. SOOD,

Osheen Jain

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(35), P. 7121 - 7127

Published: Jan. 1, 2024

We introduced, for the first time, N -methoxyamide directed proximal C–H bond activation of imidazo[1,2- a ]pyridines C(sp 2 )–C(sp ) formation via transition metal catalysed approach to obtain C-5 arylated ]pyridines.

Language: Английский

Citations

0