Multisite Dopamine Sensing With Femtomolar Resolution Using a CMOS Enabled Aptasensor Chip DOI Creative Commons
V. Sessi, Bergoi Ibarlucea, Florent Seichepine

et al.

Frontiers in Neuroscience, Journal Year: 2022, Volume and Issue: 16

Published: June 3, 2022

Many biomarkers including neurotransmitters are found in external body fluids, such as sweat or saliva, but at lower titration levels than they present blood. Efficient detection of thus requires, on the one hand, to use techniques offering high sensitivity, and, other a miniaturized format carry out diagnostics minimally invasive way. Here, we hybrid integration bottom-up silicon-nanowire Schottky-junction FETs (SiNW SJ-FETs) with complementary-metal-oxide-semiconductor (CMOS) readout and amplification electronics establish robust biosensing platform 32 × aptasensor measurement sites 100 μm pitch. The applied hetero-junctions yield selective biomolecular down femtomolar concentrations. Selective multi-site dopamine is demonstrated an outstanding sensitivity ∼1 V/fM. integrated offers great potential for detecting dilution could be applied, example, diagnosing neurodegenerative diseases monitoring therapy progress based patient samples, tear liquid, eccrine sweat.

Language: Английский

Advances in silicon nanowire applications in energy generation, storage, sensing, and electronics: a review DOI
Srinivasan Raman,

A. Ravi Sankar,

M. Sindhuja

et al.

Nanotechnology, Journal Year: 2023, Volume and Issue: 34(18), P. 182001 - 182001

Published: Jan. 14, 2023

Nanowire-based technological advancements thrive in various fields, including energy generation and storage, sensors, electronics. Among the identified nanowires, silicon nanowires (SiNWs) attract much attention as they possess unique features, high surface-to-volume ratio, electron mobility, bio-compatibility, anti-reflection, elasticity. They were tested domains of (thermoelectric, photo-voltaic, photoelectrochemical), storage (lithium-ion battery (LIB) anodes, super capacitors), sensing (bio-molecules, gas, light, etc). These nano-structures found to improve performance system terms efficiency, stability, sensitivity, selectivity, cost, rapidity, reliability. This review article scans summarizes significant developments that occurred last decade concerning application SiNWs fields thermoelectric, photovoltaic, photoelectrochemical power generation, using LIB biosensing, disease diagnostics, gas pH sensing, photodetection, physical The functionalization with nanomaterials formation heterostructures for achieving improved characteristics are discussed. will be helpful researchers field nanotechnology about possible applications improvements can realized SiNW.

Language: Английский

Citations

46

Silicon Nanowires for Gas Sensing: A Review DOI Creative Commons
Mehdi Akbari-Saatlu, Marcin Procek, Claes Mattsson

et al.

Nanomaterials, Journal Year: 2020, Volume and Issue: 10(11), P. 2215 - 2215

Published: Nov. 6, 2020

The unique electronic properties of semiconductor nanowires, in particular silicon nanowires (SiNWs), are attractive for the label-free, real-time, and sensitive detection various gases. Therefore, over past two decades, extensive efforts have been made to study gas sensing function NWs. This review article presents recent developments related applications SiNWs sensing. content begins with basic synthesis approaches (top-down bottom-up) whereby advantages disadvantages each approach discussed. Afterwards, mechanism both resistor field effect transistor designs briefly described sensitivity selectivity gases after different functionalization methods further presented. In final words, challenges future opportunities

Language: Английский

Citations

126

Aptamer‐functionalized field‐effect transistor biosensors for disease diagnosis and environmental monitoring DOI Creative Commons
Jingfeng Wang, Duo Chen,

Wanting Huang

et al.

Exploration, Journal Year: 2023, Volume and Issue: 3(3)

Published: May 11, 2023

Nano-biosensors that are composed of recognition molecules and nanomaterials have been extensively utilized in disease diagnosis, health management, environmental monitoring. As a type nano-biosensors, molecular specificity field-effect transistor (FET) biosensors with signal amplification capability exhibit prominent advantages including fast response speed, ease miniaturization, integration, promising their high sensitivity for detection identification. With intrinsic characteristics stability structural tunability, aptamer has become one the most commonly applied biological units FET sensing fields. This review summarizes recent progress based on functionalized medical diagnosis The structure, principles, preparation methods, functionalization strategies modified were comprehensively summarized. relationship between structure performance was reviewed. Furthermore, challenges future perspectives also discussed, so as to provide support development efficient healthcare management monitoring devices.

Language: Английский

Citations

39

Serum CRP biomarker detection by using carbon nanotube field-effect transistor (CNT-FET) immunosensor DOI
Gulam Rabbani, Mohammad Ehtisham Khan, Ejaz Ahmad

et al.

Bioelectrochemistry, Journal Year: 2023, Volume and Issue: 153, P. 108493 - 108493

Published: June 21, 2023

Language: Английский

Citations

34

Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies DOI Creative Commons
Diana Isabel Sandoval Bojórquez, Željko Janićijević, Brenda Palestina Romero

et al.

ACS Sensors, Journal Year: 2023, Volume and Issue: 8(2), P. 576 - 586

Published: Feb. 10, 2023

Detection of antigens and antibodies (Abs) is great importance in determining the infection immunity status population, as they are key parameters guiding handling pandemics. Current point-of-care (POC) devices a convenient option for rapid screening; however, their sensitivity requires further improvement. We present an interdigitated gold nanowire-based impedance nanobiosensor to detect COVID-19-associated (receptor-binding domain S1 protein SARS-CoV-2 virus) respective Abs appearing during after infection. The electrochemical spectroscopy technique was used assess changes measured resulting from binding analytes surface chip. After 20 min incubation, sensor demonstrate high about 57 pS·s

Language: Английский

Citations

25

Microbial nanowires for sustainable electronics DOI
Matthew J. Guberman‐Pfeffer, Noémie‐Manuelle Dorval Courchesne, Derek R. Lovley

et al.

Nature Reviews Bioengineering, Journal Year: 2024, Volume and Issue: 2(10), P. 869 - 886

Published: July 4, 2024

Language: Английский

Citations

10

Novel fabrication techniques for ultra-thin silicon based flexible electronics DOI Creative Commons
Ju Young Lee,

Jeong Eun Ju,

Chan‐Woo Lee

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 6(4), P. 042005 - 042005

Published: May 9, 2024

Abstract Flexible electronics offer a multitude of advantages, such as flexibility, lightweight property, portability, and high durability. These unique properties allow for seamless applications to curved soft surfaces, leading extensive utilization across wide range fields in consumer electronics. applications, example, span integrated circuits, solar cells, batteries, wearable devices, bio-implants, robotics, biomimetic applications. Recently, flexible electronic devices have been developed using variety materials organic, carbon-based, inorganic semiconducting materials. Silicon (Si) owing its mature fabrication process, excellent electrical, optical, thermal properties, cost efficiency, remains compelling material choice Consequently, the research on ultra-thin Si context is studied rigorously nowadays. The thinning crucially important it reduces bending stiffness resultant strain, thereby enhancing flexibility while preserving exceptional properties. This review provides comprehensive overview recent efforts techniques forming top-down bottom-up approaches explores their

Language: Английский

Citations

9

Pd-Decorated SnO2 Nanofilm Integrated on Silicon Nanowires for Enhanced Hydrogen Sensing DOI Creative Commons
Te‐Hua Fang,

Ting‐Shan Mo,

Xiao Xu

et al.

Sensors, Journal Year: 2025, Volume and Issue: 25(3), P. 655 - 655

Published: Jan. 23, 2025

The development of reliable, highly sensitive hydrogen sensors is crucial for the safe implementation hydrogen-based energy systems. This paper proposes a novel way to enhance performance through integrating Pd-SnO2 nanofilms on substrate with silicon nanowires (SiNWs). samples were fabricated via simple and cost-effective process, mainly consisting metal-assisted chemical etching (MaCE) electron beam evaporation. Structural morphological characterizations conducted using scanning microscopy (SEM) X-ray photoelectron spectroscopy (XPS). experimental results showed that, compared those without SiNW structure or decorative Pd nanoparticles, Pd-decorated SnO2 nanofilm integrated substrates exhibited significantly improved sensing performance, achieving response time 9 s at 300 °C 1.5% H2 detection limit 1 ppm. enhanced can be primarily attributed large surface area provided by SiNWs, efficient spillover effect facilitated abundant oxygen vacancies present nanofilm, as well Schottky barrier formed heterojunction interface between SnO2. study demonstrates promising approach developing high-performance characterized ultrafast times ultralow limits.

Language: Английский

Citations

1

Fabrication of piezoresistive Si nanorod-based pressure sensor arrays: A promising candidate for portable breath monitoring devices DOI Creative Commons
Ramesh Ghosh, Minho Song,

JunBeom Park

et al.

Nano Energy, Journal Year: 2020, Volume and Issue: 80, P. 105537 - 105537

Published: Oct. 27, 2020

This paper reports on the controlled fabrication of a highly sensitive piezoresistive sensor by using Si nanorod (NR) arrays. An efficient, large-area, scalable strategy was adopted to fabricate pressure sensors incorporating chemically etched, high-aspect-ratio, vertical NR arrays between two thin Au layers. The properties corresponding dimension- and position-controlled randomly closely packed, were exploited small, portable, device-compatible sensors. Si-NR-based exhibited high sensitivity 0.49 MPa−1, thereby demonstrating its superiority over other unconventional nanomaterials such as with different configurations nanostructures. Furthermore, large variation (~45%) in current at constant bias voltage 2 V under weak applied an inert gas flow 5 sccm. excellent sensing performance NRs enabled efficient detection changes human breathing pattern. In particular, key advantages is simple, inexpensive, process; ultra-low-pressure detection; ambient stability (>several months) durability pertaining more than 1,000 cycles loading/unloading. we demonstrated ability act portable breath monitor respiratory parameters noninvasive personalized manner. results can provide direction for realization next-generation breath-sensing gadgets leading-edge applications domain electronic healthcare devices.

Language: Английский

Citations

70

Hybrid Silicon Nanowire Devices and Their Functional Diversity DOI Creative Commons
Larysa Baraban, Bergoi Ibarlucea, Eunhye Baek

et al.

Advanced Science, Journal Year: 2019, Volume and Issue: 6(15)

Published: June 3, 2019

In the pool of nanostructured materials, silicon nanostructures are known as conventionally used building blocks commercially available electronic devices. Their application areas span from miniaturized elements devices and circuits to ultrasensitive biosensors for diagnostics. this Review, current trends in developments nanowire-based summarized, their functionalities, novel architectures, applications discussed point view analog electronics, arisen ability (bio)chemical gating carrier channel. Hybrid introduced described systems decorated by, e.g., organic complexes (biomolecules, polymers, films), aimed substantially extend functionality, compared traditional systems. functional diversity is explored considering architecture well applications, outlining several groups that benefit coatings. The first group able represent label-free assays thanks attached biological receptors. second represented by optoelectronics acquire higher optical sensitivity or efficiency due specific photosensitive decoration nanowires. Finally, so-called new bioinspired neuromorphic shown, which mimic functions cells, neurons synapses.

Language: Английский

Citations

66