International Journal of Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 9, 2024
Currently,
clinical
practice
and
scientific
research
mostly
revolve
around
a
single
disease
or
system,
but
the
disease-oriented
diagnostic
therapeutic
paradigm
needs
to
be
revised.
This
review
describes
how
transcutaneous
auricular
vagus
nerve
stimulation
(taVNS),
novel
non-invasive
neuromodulation
approach,
connects
central
peripheral
systems
of
body.
Through
widely
distributed
from
head
abdominal
cavity,
this
therapy
can
improve
treat
system
disorders,
central-peripheral
comorbidities
caused
by
autonomic
dysfunction.
In
past,
on
taVNS
has
focused
treatment
disorders
modulating
brain
nerve.
As
innervates
heart,
lungs,
liver,
pancreas,
gastrointestinal
tract,
spleen
other
organs,
could
have
an
overall
modulatory
effect
region
body
where
is
widespread.
Based
physiological
basis,
authors
summarize
existing
evidence
ability
regulate
cardiac
function,
adiposity,
glucose
levels,
immune
among
others,
diseases,
complex
diseases
with
comorbidities.
shows
successful
examples
progress
using
mechanisms
more
perspectives,
demonstrating
expanded
scope
value
provide
new
ideas
approaches
for
holistic
both
perspectives.
Diabetic
peripheral
neuropathy
(DPN)
constitutes
a
debilitating
complication
associated
with
diabetes.
Although,
the
past
decade
has
seen
rapid
developments
in
understanding
complex
etiology
of
DPN,
there
are
no
approved
therapies
that
can
halt
development
or
target
damaged
nerve.
Therefore,
clarifying
pathogenesis
DPN
and
finding
effective
treatment
crucial
issues
for
clinical
management
DPN.
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
14
Published: Jan. 16, 2024
Objective
To
examine
the
association
between
weight-adjusted
waist
index
(WWI)
and
odds
of
type
2
diabetes
mellitus(T2DM)among
U.S.
adults.
Methods
Data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
spanning
six
years
(2007–2018)
were
utilized,
encompassing
31001
eligible
participants.
Weighted
multivariate
logistic
regression
models
smoothed
fit
curves
employed
to
assess
WWI
T2DM,
as
well
dose-response
relationships
in
overall
population
T2DM
various
subgroups.
Results
In
fully
adjusted
continuous
model,
each
one-unit
increase
was
associated
with
a
1.14-fold
within
entire
study
(2.14
[1.98,2.31],
P
<
0.0001).
categorical
when
using
lowest
tertile
(T1)
reference
group,
second
(T2)
third
(T3)
0.88-fold
(1.88
[1.64,2.17],
0.0001)
2.63-fold
(3.63
[3.11,4.23],
T2DM.
These
findings
indicated
positive
correlation
values
aligning
results
smoothed-fitted
curves.
analysis
subgroups,
addition
maintaining
consistency
results,
we
found
interactions
age
hypertension
Conclusion
conclusion,
be
positively
International Journal of Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 9, 2024
Currently,
clinical
practice
and
scientific
research
mostly
revolve
around
a
single
disease
or
system,
but
the
disease-oriented
diagnostic
therapeutic
paradigm
needs
to
be
revised.
This
review
describes
how
transcutaneous
auricular
vagus
nerve
stimulation
(taVNS),
novel
non-invasive
neuromodulation
approach,
connects
central
peripheral
systems
of
body.
Through
widely
distributed
from
head
abdominal
cavity,
this
therapy
can
improve
treat
system
disorders,
central-peripheral
comorbidities
caused
by
autonomic
dysfunction.
In
past,
on
taVNS
has
focused
treatment
disorders
modulating
brain
nerve.
As
innervates
heart,
lungs,
liver,
pancreas,
gastrointestinal
tract,
spleen
other
organs,
could
have
an
overall
modulatory
effect
region
body
where
is
widespread.
Based
physiological
basis,
authors
summarize
existing
evidence
ability
regulate
cardiac
function,
adiposity,
glucose
levels,
immune
among
others,
diseases,
complex
diseases
with
comorbidities.
shows
successful
examples
progress
using
mechanisms
more
perspectives,
demonstrating
expanded
scope
value
provide
new
ideas
approaches
for
holistic
both
perspectives.
