MedComm,
Journal Year:
2025,
Volume and Issue:
6(5)
Published: April 24, 2025
ABSTRACT
Hydrogels
have
emerged
as
dependable
candidates
for
tissue
repair
because
of
their
exceptional
biocompatibility
and
tunable
mechanical
properties.
However,
conventional
hydrogels
are
vulnerable
to
damage
owing
stress
environmental
factors
that
compromise
structural
integrity
reduce
lifespan.
In
contrast,
self‐healing
with
inherent
ability
restore
structure
function
autonomously
offer
prolonged
efficacy
enhanced
appeal.
These
can
be
engineered
into
innovative
forms
including
stimulus‐responsive,
self‐degradable,
injectable,
drug‐loaded
variants,
thereby
enhancing
applicability
in
wound
healing,
drug
delivery,
engineering.
This
review
summarizes
the
categories
mechanisms
hydrogels,
along
biomedical
applications,
repair,
biosensing.
Tissue
includes
bone‐related
nerve
cardiac
repair.
Additionally,
we
explored
challenges
continue
face
presented
a
forward‐looking
perspective
on
development.
Consequently,
it
is
anticipated
will
progressively
designed
developed
applications
extend
beyond
broader
range
applications.
Biomimetics,
Journal Year:
2025,
Volume and Issue:
10(2), P. 125 - 125
Published: Feb. 19, 2025
The
sector
of
4D
printing
represents
a
new
frontier
in
additive
manufacturing
that
allows
for
material's
capability
to
adapt
and
respond
various
stimuli,
such
as
thermal
transitions,
humidity,
pH
levels.
adaptability
material
has
great
potential
healthcare
applications,
especially
designing
personalized
responsive
medical
devices.
This
article
looks
into
the
revolutionary
applications
printing,
referencing
self-repairable
implants,
smart
stents,
drug
delivery
systems,
response-based
prosthetic
advances
3D
have
created
platform
innovations
take
place,
while
properties
unique
allow
methods
tackling
existing
health
issues.
However,
large-scale
application
medicine
is
currently
hampered
by
limitations,
regulation
challenges,
financial
challenges.
In
spite
these
ongoing
technologies,
combined
with
artificial
intelligence
machine
learning,
provide
surpass
hence
improving
precision,
efficacy,
personalization
work
outlines
at
areas
future,
analyzes
contributing
healthcare,
recognizing
challenges
need
be
overcome
order
unlock
its
full
potential.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(47)
Published: Nov. 18, 2024
Abstract
Skin
wounds
have
become
an
important
issue
that
affects
human
health
and
burdens
global
medical
care.
Hydrogel
materials
similar
to
the
natural
extracellular
matrix
(ECM)
are
one
of
best
candidates
for
ideal
wound
dressings
most
feasible
choices
printing
inks.
Distinct
from
hydrogels
made
by
traditional
technologies,
which
lack
bionic
mechanical
properties,
3D
can
promptly
accurately
create
with
complex
bioactive
structures
potential
promote
tissue
regeneration
healing.
Herein,
a
comprehensive
review
multi‐functional
printing‐based
hydrogel
healing
is
presented.
The
first
summarizes
techniques
dressings,
including
photo‐curing,
extrusion,
inkjet,
laser‐assisted
printing.
Then,
properties
design
approaches
series
bioinks
composed
natural,
synthetic,
composite
polymers
described.
Thereafter,
application
in
variety
environments
discussed
depth,
hemostasis,
anti‐inflammation,
antibacterial,
skin
appendage
regeneration,
intelligent
monitoring,
machine
learning‐assisted
therapy.
Finally,
challenges
prospects
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
12
Published: Jan. 10, 2025
Bacterial
infection,
a
complex
wound
microenvironment,
and
persistent
inflammatory
response
in
acute
wounds
can
result
delayed
healing
abnormal
scar
formation,
thereby
compromising
the
normal
function
aesthetic
appearance
of
skin
tissue.
This
issue
represents
one
most
challenging
problems
clinical
practice.
study
aims
to
develop
hydrogel
dressing
specifically
designed
for
treatment
wounds,
providing
immediate
effective
protection
affected
areas.
innovation
seeks
offer
novel
advanced
solution
management
wounds.
In
this
study,
composite
scaffold
was
synthesized
through
reaction
between
oxidized
glycyrrhizic
acid
carboxymethyl
chitosan
Schiff
base.
The
material
properties
were
systematically
characterized,
its
biocompatibility
antibacterial
efficacy
rigorously
evaluated.
A
rat
model
established
compare
multiple
groups,
assessing
impact
on
microenvironment
repair.
results
demonstrated
that
OGA-CMCS
exhibited
excellent
injectability,
biocompatibility,
properties.
It
capable
enhancing
which
turn
influenced
polarization
macrophages
from
M1
M2
phenotype,
mitigating
response,
promoting
angiogenesis
granulation
tissue
regeneration,
accelerating
healing.
successfully
developed
glycyrrhizin-based
dressing,
not
only
introduces
innovative
approaches
emergency
surface
defects
but
also
provides
an
experimental
foundation.
is
anticipated
contribute
significantly
addressing
relevant
challenges.
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(2), P. 249 - 249
Published: Feb. 14, 2025
Gels
constitute
a
versatile
class
of
materials
with
considerable
potential
for
applications
in
both
technical
and
medical
domains.
Physicochemical
property
characterization
is
critical
evaluation
method
gels.
Common
techniques
include
pH
measurement,
structural
analysis,
mechanical
assessment,
rheological
phase
transition
studies,
among
others.
While
numerous
research
articles
report
results,
few
reviews
comprehensively
summarize
the
appropriate
numerical
ranges
these
properties.
This
lack
standardization
complicates
harmonized
methods
hinders
direct
comparisons
between
different
To
address
this
gap,
it
essential
to
systematically
investigate
analyze
data
from
extensive
body
literature
on
In
review,
we
provide
comprehensive
summary
general
present
detailed
analysis
gel
support
future
promote
standardized
protocols.
Polymers,
Journal Year:
2025,
Volume and Issue:
17(7), P. 886 - 886
Published: March 26, 2025
Three-dimensional
(3D)
printing
is
a
cutting-edge
technology
that
widely
used
in
biomedical
fields
to
construct
various
commercial
products
or
scaffolds
for
theoretical
research.
In
this
review,
3D
technologies
with
different
principles
are
briefly
introduced,
including
selective
laser
melting
(SLM),
sintering
(SLS),
fused
deposition
modeling
(FDM),
stereolithography
(SLA),
and
digital
light
processing
(DLP).
addition,
the
applications
of
dentistry,
such
as
dental
implantology,
prosthodontics,
orthodontics,
maxillofacial
surgery,
tissue
regeneration,
were
summarized.
Furthermore,
perspective
challenges
also
addressed
help
readers
obtain
clear
map
development
dentistry.
