A Wireless Health Monitoring System Accomplishing Bimodal Decoupling Based on an “IS”‐Shaped Multifunctional Conductive Hydrogel

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 6, 2025

Abstract Flexible wearable sensors with bimodal functionality offer substantial value for human health monitoring, as relying on a single indicator is insufficient capturing comprehensive physiological information. However, face multiple challenges in practical applications, including mutual interference between various modalities, and integration of excellent mechanical properties, interfacial adhesion, environmental adaptability biocompatibility. Herein, the multifunctional hydrogel, synthesized through radical grafting supramolecular self‐crosslinking reactions, exhibits thermal sensitivity (TCR = −1.70% °C −1 ), high toughness (9.31 MJ m − 3 wide strain range (0–600%), outstanding adhesion strength (36.07 kPa), antifreeze, visualization, water retention, biocompatibility, antibacterial antioxidant capabilities. Leveraging its conductivity, this hydrogel can be applied electroluminescent, triboelectricity, electromyography message encryption. Moreover, fabricated smart temperature monitoring. To avoid two signals, system “IS”‐shaped configuration innovatively designed based finite element simulation results. The flexible circuit modules, data transmission form closed‐loop platform rehabilitation training patients arthritis or joint surgery. This strategy establishes decoupling self‐calibrating utilizing material to accurately detect parameters, advancing electronics personalized medicine.

Language: Английский

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Ways forward with conductive hydrogels: Classifications, properties, and applications in flexible electronic and energy gadgets

Materials Science and Engineering R Reports, Journal Year: 2025, Volume and Issue: 163, P. 100923 - 100923

Published: Jan. 8, 2025

Language: Английский

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Engineered hydrogel platform for diabetic wound healing

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160379 - 160379

Published: Feb. 1, 2025

Language: Английский

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Ultrafine‐Mn‐Loaded N,O‐Doped Nanocarbon via Mott‒Schottky Effect for Photo‐Enhanced Antibacterial Therapy and Wound Healing

Aggregate, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

ABSTRACT Bacterial infections are one of the greatest threats to wound healing, and microbial resistance has increased demand for new antimicrobial dressings. Artificial nanozymes possess myriad considerable advantages, including low cost high activity, targeted biological treatments. Despite significant efforts made in nanozyme engineering, challenge remains that their catalytic performance is far from satisfactory treatment. Herein, based on biowaste valorisation, we propose a sustainable efficient strategy synthesize an ultrafine‐Mn‐loaded (3.0 ± 1 nm) N,O‐doped porous nanocarbons (Mn‐PNCs) via Mott−Schottky effect. The achieves mid‐temperature (45.8°C) superior photothermal conversion efficiency (77.62%), photothermally enhanced peroxidase‐like activity contributes effective treatment methicillin‐resistant Staphylococcus aureus ‐infected wounds. photo‐enzyme platform further reduced inflammatory response, normalized epidermal tissue regeneration, accelerated healing. Notably, mechanism demonstrated this catalyst can trigger rapid transfer electrons release reactive oxygen species (ROS) species, as heterojunction system strongly capable changing electron density within metal. Under induction, Mott–Schottky contact be used fabricate other polysaccharide‐derived or high‐value application biomass resources.

Language: Английский

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Skin‐Inspired and Self‐Regulated Hydrophobic Hydrogel for Diabetic Wound Therapy

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Diabetic wounds are refractory and recurrent diseases that necessitate the development of multifunctional dressings. Inspired by structure function skin, we herein delicately design a novel swollen hydrophobic hydrogel (QL@MAB) composed methyl acrylate (MA) (3-acrylamidophenyl)boronic acid (AAPBA) network co-loaded with antioxidant quercetin (Q) antibiotic levofloxacin (L) for efficient diabetic wound therapy. The MA segments undergo phase separation to form dense "epidermis", ensuring prolonged drug diffusion, long-term water retention, high content. Meanwhile, AAPBA generate glucose-labile "sweat pores" via borate ester bonds polyphenol Q. Upon encountering hyperglycemic microenvironment, dilated due cleavage exposure diffusion channel, facilitating release accelerated healing. In infected rats, QL@MAB achieves rapid debridement re-epithelization while promoting angiogenesis, hair follicle regeneration, extracellular matrix remodeling. Taken together, this study not only represents multipronged dressing effective interventions but also contributes rational smart hydrogels tailored biomedical applications.

Language: Английский

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Circularity of Smart Products and Textiles Containing Flexible Electronics: Challenges, Opportunities, and Future Directions

Sensors, Journal Year: 2025, Volume and Issue: 25(6), P. 1787 - 1787

Published: March 13, 2025

The integration of flexible electronics into textiles and smart products has revolutionized industries, enabling innovations such as wearable health monitors, interactive clothing, energy-harvesting fabrics. However, the rapid growth these technologies poses significant challenges for sustainability circularity. This paper explores concept circular economy in context containing electronics. It highlights technical, environmental, economic associated with their end-of-life management proposes strategies to enhance circularity, including design disassembly, advanced recycling technologies, policy frameworks. concludes a discussion future research directions achieve sustainable lifecycle materials.

Language: Английский

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Thermoresponsive and Strain-Sensitive Hydrogels with Inscribable Transparency-Based Dynamic Memory Behaviors

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 28, 2025

Personal health management drives the development of intelligent hydrogel dressings, which pursue optical transparency, stretchability, and conductivity are required to perceive specific environmental stimuli by dynamic structure, shape, or color memory. However, incorporation weak perceptive elements black conductive polymers limits fabrication these hydrogels. Herein, we propose smart hydrogels with inscribable memorizing-forgetting transparency behavior in situ degrading immobilizing polydopamine-doped polypyrrole (PDA-PPy) nanodots into an interpenetrating poly(NIPAm-co-acrylic acid) copolymer/polyacrylamide (PNAc/PAM) network. These not only optically transparent (∼64.99%), stretchable (∼1052%), self-adhesive (21-105 kPa), highly (∼0.8 S/m), but also can temperature changes via structure shifts, enables temperature-induced reversible control. Especially, temperature-dependent transparent-opaque transition kinetics tuned protonation -COOH groups at pH < pKa, utilizing achieve inscribed programmed memory for information memorizing-forgetting-recalling based on a pH-engraved evolution response changes. be used as efficient near-infrared (NIR) light-controlled drug release carriers realize on-demand release, serve soft sensor recognize different body postures movement behaviors high strain sensitivity (gauge factor, GF = 5.98), broad working (5-500%), rapid (139 ms), excellent sensing reliability (≈1000 cycles 50% strain).

Language: Английский

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Design and Application of Stimuli‐Responsive Nanocomposite Hydrogels: A Review

Macromolecular Rapid Communications, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Abstract In order to improve the disadvantages of traditional hydrogels such as low mechanical strength and lack responsiveness, different types nanoparticles or nanostructures are added into hydrogel network through in situ polymerization, self‐assembly techniques, other strategies, giving a variety special properties, stimulation sensitivity, optical electrical reversibility. With development nano materials synthesis technology, nanocomposite have shown great potential drug delivery, tissue engineering, motion detection, wastewater treatment, been extensively studied recent years. This review comprehensively elucidates state‐of‐the‐art preparation strategies underlying response mechanisms diverse stimulus‐responsive hydrogels, spanning temperature, pH, humidity, electrical, light responses. It systematically dissects their applications biomedicine, environmental remediation, flexible sensing, composite phase change materials. Moreover, it delves future prospects challenges, emphasizing need for continuous innovation unlock full emerging fields address existing limitations.

Language: Английский

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Porous oxidized dextran sponges for surgical hemostasis and infection control

Journal of Biomaterials Applications, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Surgical procedures frequently result in varying degrees of bleeding and infection, which can impede patient recovery, particularly situations limited blood supply. Minimizing surgical loss preventing infections remain crucial clinical challenges. To address these tissues, we developed a porous hemostatic sponge by aldehyde-functionalizing dextran. The high porosity absorption capacity ODex sponges enables them to effectively concentrate red cells, platelets, coagulation factors, forming clot together with the matrix. aldehyde groups bind amines tissue, helping seal site. This innovation significantly reduced clotting times both vitro vivo experiments. Furthermore, demonstrated excellent biocompatibility potent antimicrobial activity. These findings highlight oxidized dextran as highly promising biomaterial strong capabilities, offering potential for broad applications.

Language: Английский

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Engineering Adhesive Hydrogels for Hemostasis and Vascular Repair

Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 959 - 959

Published: April 1, 2025

Adhesive hydrogels with tunable mechanical properties and strong adhesion to wet, dynamic tissues have emerged as promising materials for tissue repair, potential applications in wound closure, hemorrhage control, surgical adhesives. This review highlights the key design principles, material classifications, recent advances adhesive designed vascular repair. The limitations of existing hydrogels, including insufficient durability, suboptimal biocompatibility, challenges targeted delivery, are critically evaluated. Furthermore, innovative strategies-such incorporating self-healing capabilities, developing stimuli-responsive systems, integrating functional nanocomposites, employing advanced fabrication techniques like 3D bioprinting-are discussed enhance adhesion, stability, regeneration. While significant progress has been made, further research optimization necessary advance these toward clinical translation, offering a versatile minimally invasive alternative traditional repair techniques.

Language: Английский

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