Nickel/Photoredox-Catalyzed Asymmetric Three-Component Cross-Coupling To Access Enantioenriched 1,1-Diaryl(heteroaryl)alkanes
Xueying Gao,
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Tingzhi Lin,
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Yan‐En Wang
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et al.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(41), P. 8792 - 8797
Published: Oct. 8, 2024
An
enantioselective
1,2-dicarbofunctionalization
of
vinyl
(hetero)arenes
with
alkyl
bromides
and
aryl
through
nickel/photoredox
catalysis
is
described.
This
three-component
domino
arylation
could
generate
a
diverse
array
enantioenriched
1,1-diaryl(heteroaryl)alkanes
good
to
excellent
yields
(up
88%)
high
enantioselectivities
99%
Language: Английский
Enantioselective Nickel-Catalyzed Electrochemical Reductive Conjugate Alkenylation of α,β-Unsaturated Ketones
Chemical Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 20, 2024
We
present
an
asymmetric
electrochemical
nickel-catalysed
reductive
conjugate
addition
of
alkenyl
bromides/aryl
iodides
to
α,β-unsaturated
ketones
in
undivided
cell,
which
afforded
β-alkenylate/arylate
high
yields
with
excellent
enantioselectivities.
Language: Английский