Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132509 - 132509
Published: March 1, 2025
Language: Английский
Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132509 - 132509
Published: March 1, 2025
Language: Английский
Published: Jan. 1, 2025
Language: Английский
Citations
0Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216543 - 216543
Published: March 4, 2025
Language: Английский
Citations
0Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)
Published: March 7, 2025
Nanozymes offer diverse therapeutic potentials for cancer treatment which is dependent on the development of nanomaterials. Quasi-metal-organic framework a class metal-organic framework-derived nanomaterials with transition state from frameworks towards metal oxide featuring porous structure and high activity. Herein an iron-based quasi-metal-organic nanozyme Q-MIL-53(Fe) reported via controlled deligandation strategy, exhibiting enhanced peroxidase-/catalase-mimic activity glutathione depletion capacity, whose underlying mechanisms are studied density functional theory calculations. demonstrates biocompatibility superior antitumor efficacy compared to pristine MIL-53(Fe). It can activate immune response by inducing ferroptosis immunogenic cell death, promoting dendritic maturation T lymphocytes infiltration. Furthermore, combination programmed death protein 1 antibody amplifies immunotherapy. This study validates its immunotherapy induction potential. would broaden application open avenues developing nanozymes. treatment. In this work, authors report quasi-metal organic peroxidase catalase-mimicking capacity use it tumor death.
Language: Английский
Citations
0Journal of Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 116076 - 116076
Published: March 1, 2025
Language: Английский
Citations
0Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132509 - 132509
Published: March 1, 2025
Language: Английский
Citations
0