Synlett,
Journal Year:
2021,
Volume and Issue:
32(13), P. 1309 - 1315
Published: March 5, 2021
Abstract
Magnesium
(Mg)
is
a
cheap,
non-toxic,
and
recyclable
alkaline
earth
metal
that
constitutes
about
2%
weight
in
the
Earth’s
crust.
The
use
of
magnesium
catalysts
to
forge
chiral
moieties
molecules
highly
attractive.
Based
on
our
work
recent
years,
we
describe
current
progress
development
situ
generated
their
application
asymmetric
synthesis.
In
this
perspective,
critically
concise
classification
catalytic
modes,
with
relevant
examples,
presented,
representative
mechanisms
each
category
are
discussed.
Building
established
diverse
strategies,
one
can
foresee
more
innovative
structurally
creative
will
be
developed
overcome
formidable
challenges
enantioselective
reactions.
1
Introduction
2
Catalysts
Generated
Situ
from
Chiral
Ligands
Containing
Dual
Reactive
Hydrogens
3
Monoanionic
4
Bimetallic
Polymetallic
Assembled
5
Summary
Outlook
Chemical Reviews,
Journal Year:
2022,
Volume and Issue:
122(9), P. 8261 - 8312
Published: March 7, 2022
The
addition
of
a
B–H
bond
to
an
unsaturated
(polarized
or
unpolarized)
is
powerful
and
atom-economic
tool
for
the
synthesis
organoboranes.
In
recent
years,
s-block
organometallics
have
appeared
as
alternative
catalysts
transition-metal
complexes,
which
traditionally
catalyze
hydroboration
bonds.
Because
rapid
development
in
field
bonds
catalyzed
by
alkali
(Li,
Na,
K)
alkaline
earth
(Mg,
Ca,
Sr,
Ba)
metals,
we
provide
detailed
updated
comprehensive
review
that
covers
synthesis,
reactivity,
application
metal
polarized
well
carbon–carbon
Moreover,
describe
main
reaction
mechanisms,
providing
valuable
insight
into
reactivity
catalysts.
Finally,
compare
these
complexes
with
other
redox-neutral
catalytic
systems
based
on
p-block
metals
including
aluminum
f-block
lanthanides
early
actinides.
this
review,
aim
comprehensive,
authoritative,
critical
assessment
state
art
within
highly
interesting
research
area.
Angewandte Chemie International Edition,
Journal Year:
2019,
Volume and Issue:
58(49), P. 17567 - 17571
Published: Oct. 23, 2019
Asymmetric
catalysis
with
readily
available,
cheap,
and
non-toxic
alkaline
earth
metal
catalysts
represents
a
sustainable
alternative
to
conventional
synthesis
methodologies.
In
this
context,
we
describe
the
development
of
first
MgII
-catalyzed
enantioselective
hydroboration
providing
products
excellent
yields
enantioselectivities.
NMR
spectroscopy
studies
DFT
calculations
provide
insights
into
reaction
mechanism
origin
enantioselectivity
which
can
be
explained
by
metal-ligand
cooperative
pathway
involving
non-innocent
ligand.
Nature Communications,
Journal Year:
2019,
Volume and Issue:
10(1)
Published: Feb. 4, 2019
Abstract
Catalytic
enantioselective
C–C
bond
forming
process
through
cross-dehydrogenative
coupling
represents
a
promising
synthetic
strategy,
but
it
remains
long-standing
challenge
in
chemistry.
Here,
we
report
formal
catalytic
of
saturated
ethers
with
diverse
carboxylic
acid
derivatives
involving
an
initial
oxidative
acetal
formation,
followed
by
nickel(II)-catalyzed
asymmetric
alkylation.
The
one-pot,
general,
and
modular
method
exhibits
wide
compatibility
broad
range
not
only
including
prevalent
tetrahydrofuran
tetrahydropyran,
also
medium-
large-sized
cyclic
moieties
acyclic
ones
excellent
enantioselectivity
functional
group
tolerance.
application
the
rapid
preparation
biologically
active
molecules
that
are
difficult
to
access
existing
methods
is
demonstrated.
Chemical Science,
Journal Year:
2020,
Volume and Issue:
11(31), P. 8184 - 8195
Published: Jan. 1, 2020
Simple
achiral
neutral
donor
ligands
modify
catalyst
structure
and
function
to
enable
access
isoenriched
poly-3-hydroxybutyrate,
a
biodegradable
material
with
properties
similar
isotactic
polypropylene.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
27(18)
Published: March 16, 2024
Abstract
We
report
the
efficient,
sustainable
one‐pot
synthesis
of
a
wide
variety
N
‐polyheterocycles,
such
as
imidazo‐quinolines
and
quinoxalines,
furoquinolines,
from
easily
available
nitroaromatics
glycols
via
molybdenum
catalytic
domino
reduction‐imine
formation‐intramolecular
cyclization‐oxidation
sequence.
It
is
worth
highlighting
that
recycling
incorporation
waste
carbonyl
byproduct,
generated
in
reduction
step,
into
final
compound
realized.
In
addition,
overall
efficiency
atom
economy
process
are
further
improved
owing
to
participation
one
reaction
intermediate
reductant
allows
lowering
amount
external
reducing
agent
employed.
Cell Reports Physical Science,
Journal Year:
2023,
Volume and Issue:
4(3), P. 101313 - 101313
Published: March 1, 2023
Dehydrogenative
coupling
of
silanes
and
hydroxyl
compounds
is
a
useful
method
for
accessing
containing
an
Si–O
bond.
Alongside
previous
advances,
practical
large-scale
dehydrogenative
catalyzed
by
available
cheap
catalytic
system
remains
appealing.
Here,
we
report
general
dimanganese
decacarbonyl-catalyzed
with
inexpensive
phosphine
oxide
ligands.
This
features
broad
substrate
scope
compounds,
producing
the
corresponding
silyl
ethers
silanols
in
moderate
to
high
yields
(>91
examples,
up
99%
yield).
N-silylated
indoles
are
also
successfully
synthesized
direct
N–H
bonds
silanes.
reaction
can
be
achieved
on
40
g
scale
only
2.5
mol
%
manganese
catalyst,
delivering
desired
ether
quantitative
yield
without
any
isolation
difficulties.
In
exploration
mechanism,
find
probable
uncommon
organometallic
pathway
controlled
ligand.
Organic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
10(13), P. 3401 - 3428
Published: Jan. 1, 2023
This
review
summarizes
the
advances
in
field
of
intramolecular
kinetic
resolution
(KR)
mediated
by
non-enzymatic
catalysts.
The
relative
classification
KR
is
accomplished
and
several
categories
reactions
are
discussed.
