Chemical Communications,
Journal Year:
2020,
Volume and Issue:
56(66), P. 9469 - 9472
Published: Jan. 1, 2020
A
photoredox-catalyzed
three-component
reaction
of
aryldiazonium
tetrafluoroborates
with
sodium
metabisulfite
and
2,2-difluoro
enol
silyl
ethers
is
described.
By
using
as
the
source
sulfur
dioxide,
this
method
provides
an
elegant
access
to
α,α-difluoro-β-ketosulfones
in
moderate
good
yields
under
mild
conditions,
features
a
broad
substrate
scope
wide
functional
group
tolerance.
Both
difluoromethyl
sulfone
moiety
can
be
introduced
single
step.
Based
on
experimental
results,
single-electron
transfer
pathway
proposed
insertion
dioxide.
Chemical Communications,
Journal Year:
2020,
Volume and Issue:
56(30), P. 4145 - 4155
Published: Jan. 1, 2020
Recently,
sulfonylation
reactions
using
potassium/sodium
metabisulfite
as
the
sulfur
dioxide
surrogate
have
been
developed
rapidly.
In
most
cases,
transformations
go
through
radical
processes
with
insertion
of
under
mild
conditions.
Additionally,
transition
metal
catalysis
is
applied
in
for
synthesis
sulfonyl-containing
compounds.
Among
approaches,
photoinduced
conversions
visible
light
or
ultraviolet
irradiation
are
also
involved.
this
updated
report,
from
potassium
sodium
summarized.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(19), P. 8351 - 8377
Published: Jan. 1, 2022
This
review
focuses
on
nickel-catalyzed
construction
and
transformation
of
various
sulfide-containing
compounds,
such
as
sulfides,
disulfides,
hypervalent
sulfur-containing
compounds.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2022,
Volume and Issue:
10(2), P. 671 - 677
Published: Jan. 3, 2022
Sulfur-containing
molecules
are
increasingly
crucial
in
chemistry-related
fields
and
widely
applied
life
science,
material
food
pharmaceutical
science.
This
perspective
focuses
on
the
introduction
of
green
sulfurizing
reagents
sustainable
methodologies
to
realize
diverse
kinds
functionalized
transformations
synthetic
applications.
The
text
is
organized
according
structure
sulfur-containing
corresponding
method.
It
expected
be
interest
organic
chemistry
professionals
who
wish
better
understand
insights
applications
organosulfur
transformations.
ACS Catalysis,
Journal Year:
2021,
Volume and Issue:
11(7), P. 4169 - 4204
Published: March 19, 2021
Arylsulfonyl
compounds
are
among
the
most
important
in
pharmaceutical
and
medicinal
chemistry.
Hence,
a
wide
variety
of
sulfonylation
methods
have
been
reported
recently.
This
review
summarizes
arylsulfonylation
methodologies
developed
last
5
years
includes
two
major
categories.
The
first
entails
direct
second
multicomponent
arylsulfonylation.
In
arylsulfonylation,
arylsulfonyl
reagents
react
with
C–H
activated
compounds,
alkynes,
alkenes
through
coupling
or
addition
reactions.
reactions,
arylation
various
substrates
sulfur
dioxide
surrogates,
such
as
DABSO,
Na2S2O5,
K2S2O5.
hydrazides,
aryl
boronic
acids,
silanes,
halides
widely
employed
that
surrogates
to
generate
an
source,
ensuing
reactions
proceed
via
pathways
analogous
those
Angewandte Chemie International Edition,
Journal Year:
2020,
Volume and Issue:
59(23), P. 8907 - 8911
Published: March 9, 2020
Abstract
A
straightforward
multicomponent
decarboxylative
cross
coupling
of
redox‐active
esters
(N‐hydroxyphthalimide
ester),
sodium
dithionite,
and
electrophiles
was
established
to
construct
sterically
bulky
sulfones.
The
inorganic
salt
dithionite
not
only
served
as
the
sulfur
dioxide
source,
but
also
acted
an
efficient
radical
initiator
for
decarboxylation.
Notably,
diverse
naturally
abundant
carboxylic
acids
artificially
prepared
carboxyl‐containing
drugs
with
multiple
heteroatoms
sensitive
functional
groups
successfully
underwent
this
sulfonylation
provide
tertiary
Mechanistic
studies
further
demonstrated
that
decarboxylation
rate‐determining
step
occurred
via
a
single‐electron
transfer
(SET)
process
assistance
dithionite.
Organic Letters,
Journal Year:
2020,
Volume and Issue:
22(8), P. 3072 - 3078
Published: March 31, 2020
A
copper-free
Sandmeyer-type
fluorosulfonylation
reaction
is
reported.
Utilizing
Na2S2O5
and
Selectfluor
as
the
sulfur
dioxide
fluorine
sources,
respectively,
aryldiazonium
salts
were
transformed
into
sulfonyl
fluorides.
The
one-pot
direct
synthesis
of
fluorides
from
aromatic
amines
was
also
realized
via
in
situ
diazotization.
practicality
this
method
demonstrated
by
broad
functional
group
tolerance,
gram-scale
synthesis,
late-stage
natural
products
pharmaceuticals.
Green Chemistry,
Journal Year:
2020,
Volume and Issue:
22(6), P. 1906 - 1910
Published: Jan. 1, 2020
A
metal-free
route
to
alkynyl
sulfones
under
photoinduced
conditions
is
accomplished,
starting
from
4-alkyl
Hantzsch
esters,
sulfur
dioxide,
and
bromides
visible
light
irradiation
at
room
temperature.
