Dextran-based micelles for combinational chemo-photodynamic therapy of tumors via in vivo chemiluminescence DOI
Chendi Ding, Zhaoqing Shi,

Meitong Ou

et al.

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 319, P. 121192 - 121192

Published: July 11, 2023

Language: Английский

A type I and type II chemical biology toolbox to overcome the hypoxic tumour microenvironment for photodynamic therapy DOI
Minzi Ju, Lu Yang, Guowei Wang

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(11), P. 2831 - 2840

Published: Jan. 1, 2024

A chemicobiology toolbox for type I and II photodynamic therapy.

Language: Английский

Citations

7
Directional Formation of Reactive Oxygen Species via a Non‐Redox Catalysis Strategy that Bypasses Electron Transfer Process DOI

Junsheng Song,

Nannan Hou,

Xiaocheng Liu

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(30)

Published: May 17, 2024

Abstract A broad range of chemical transformations driven by catalytic processes necessitates the electron transfer between catalyst and substrate. The redox cycle limitation arising from inequivalent donation acceptance involved catalysts, however, generally leads to their deactivation, causing substantial economic losses environmental risks. Here, a “non‐redox catalysis” strategy is provided, wherein units are constructed atomic Fe B as dual active sites create tensile force electric field, which allows directional self‐decomposition peroxymonosulfate (PMS) molecules through internal form singlet oxygen, bypassing need PMS. proposed approach with non‐redox cycling contributes excellent stability centers while generated reactive oxygen species find high efficiency in long‐term pollutant degradation selective organic oxidation synthesis aqueous phase. This work offers new avenue for substrate conversion, holds promise advance design alternative pathways sustainable energy conversion valuable production.

Language: Английский

Citations

7
Activatable Phototherapeutic Prodrug Conquering Hypoxia Limitation to Enhance Chemical Drug Delivery Efficiency DOI
Jianhua Xiong, Weijie Chi, Miantai Ye

et al.

ACS Materials Letters, Journal Year: 2024, Volume and Issue: 6(7), P. 2548 - 2558

Published: May 24, 2024

Chemotherapy faces critical challenges in clinical oncology treatment. One primary reason is the tumor hypoxia that obstructs penetration of chemotherapeutic drugs into solid tumors and diminishes drug concentration cells, leading to suboptimal treatment outcomes. Thereupon, we create a self-immolative phototherapeutic prodrug (DHQ-AZO-BIO) featured with targeting activation. First, heavy-atom-free photosensitizer based on intramolecular noncovalent interactions (NCIs), which specifically enriches produces photocytotoxic 1O2 eliminate normoxic cells surface layer by photodynamic therapy (PDT). Second, PDT process also increases hypoxic degree within tumor, thereby improving on-demand release action efficiency hypoxia-sensitive prodrug. This combined fashion synergizes hypoxia-activated chemotherapy overcome limitation augment therapeutic index for tumors, contributing development delivery systems (DDSs) precise phototherapy tumors.

Language: Английский

Citations

7
Design strategies and applications of cyanine dyes in phototherapy DOI
Jie Yuan, Han‐xue Yang,

Wenhui Huang

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

An overview of cyanine dye-based phototherapy agents, including the design strategies, relationships between molecular structures and properties, as well applications in photodynamic therapy, photothermal multimodal combined therapy.

Language: Английский

Citations

6
Dextran-based micelles for combinational chemo-photodynamic therapy of tumors via in vivo chemiluminescence DOI
Chendi Ding, Zhaoqing Shi,

Meitong Ou

et al.

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 319, P. 121192 - 121192

Published: July 11, 2023

Language: Английский

Citations

15