ACS Catalysis,
Journal Year:
2023,
Volume and Issue:
13(19), P. 12803 - 12809
Published: Sept. 18, 2023
In
this
article,
we
report
an
efficient
hybrid
photoredox
catalyst
that
combines
N-arylbenzophenothiazine
and
a
boronic
acid.
The
forms
complex
with
the
substrate
to
enable
single
electron
reduction
of
redox-inactive
carboxy
groups
under
visible-light
irradiation.
Via
approach,
two
types
radical
cyclization
α,β-unsaturated
carboxylic
acids
previously
required
harsh
reaction
conditions
can
be
achieved,
i.e.,
[2
+
2]
cycloaddition
reductive
cyclization.
Mechanistic
studies
have
revealed
photocatalyst
promotes
transfer
toward
generally
unreactive
cyclobutane
acid
moieties
adducts
as
well
acids,
leading
unusual
cis–trans
isomerization
rings
via
reversible
ring-opening/-closing
process.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 14, 2025
Abstract
We
present
a
simple
and
efficient
photocatalytic
method
for
the
transfer
hydrogenation
of
alkenes
alkynes
using
alcohol
as
hydrogen
source
inexpensive
decatungstate
photocatalyst.
Our
approach
operates
under
mild,
ambient
conditions
demonstrates
broad
substrate
compatibility,
accommodating
alkyl,
aryl,
heteroatom-substituted
alkynes.
To
our
knowledge,
this
study
represents
first
instance
tungsten-based
catalysts
alkenes.
Notably,
decatungstate/alcohol
catalytic
system
exhibits
excellent
chemoselectivity,
enabling
selective
even
in
presence
reactive
groups
like
ketones
carboxylic
acids.
These
features
highlight
considerable
potential
practical
sustainable
applications
organic
synthesis.
Chemical Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Employing
water
as
a
hydrogen
source
is
an
attractive
and
sustainable
option
in
electricity-driven
organic
hydrogenation,
which
can
overcome
the
drawbacks
associated
with
traditional
sources
like
H
2
.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(42), P. 7633 - 7638
Published: Oct. 16, 2023
The
chemical
activation
and
functionalization
of
water
are
considered
an
ideal
method
for
converting
earth-abundant
sources
into
valuable
chemicals.
Here,
we
show
that
a
non-activated
free
molecule
can
be
applied
directly
as
hydrogen
donor
to
achieve
the
carbanion-mediated
alkene
reduction
with
9-HTXTF
serving
organophotocatalyst.
Notably,
direct
syntheses
high-value-added
drugs
bioactive
molecules
readily
achieved
by
utilizing
plentiful
energy
resource,
showcasing
usefulness
protocol
in
synthesis.
Advanced Synthesis & Catalysis,
Journal Year:
2023,
Volume and Issue:
365(24), P. 4684 - 4691
Published: Nov. 11, 2023
Abstract
We
demonstrate
a
photocatalyst
and
transition
metal
catalyst
free
photo‐activation
of
quinoxalin‐2(1
H
)‐ones
in
visible
light
the
presence
an
acid
catalyst.
The
photoactivated
)‐one
species
transfers
its
energy
to
oxygen
which
promotes
C−N
cross
dehydrogenative
coupling
with
nucleophilic
partners
such
as
carbazoles,
azoles
amides
giving
products
42–75%
yields.
Preliminary
studies
reveal
)‐one‐carbazole
adducts
display
fluorescent
properties
including
Intramolecular
Charge
Transfer
(ICT)
Aggregate
Induced
Emission
(AIE).
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(2), P. 1353 - 1360
Published: Jan. 8, 2024
We
have
developed
a
visible
light-induced
intermolecular
[2
+
2]-cycloaddition
reaction
between
alkenes
and
alkynes
using
thioxanthone
Cu(OTf)2
as
cocatalysts.
Various
quinolin-2(1H)-ones,
featuring
diverse
substituted
groups,
were
successfully
employed
in
this
reaction,
resulting
the
synthesis
of
series
4,8b-dihydrocyclobuta[c]quinolin-3(2aH)-ones.
Our
methodology
presents
novel
synthetic
approach
for
alkene-alkyne
2]-cycloaddition,
delivering
cyclobutene
derivatives
with
exceptional
regioselectivity.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(15), P. 3267 - 3272
Published: April 4, 2024
This
study
addresses
the
challenges
associated
with
vinyl
cation
generation,
a
process
that
traditionally
requires
quite
specific
counterions.
Described
herein
is
novel
intramolecular
vinylation
of
arenes
catalyzed
by
aluminum(III)
chloride,
utilizing
practical
conditions
and
readily
available
triflates
derived
from
2-aceto-3-arylpropionates.
Comprehensive
experimental
data
support
diverse
carbocycle
synthesis,
exemplified
indenes
higher
analogues.
Control
experiments
verify
applicability
protocol,
synthetic
applications
showcase
potent
tubulin
polymerization
inhibitor
anticancer
properties.
Density
functional
theory
computations
reveal
Lewis-acid-driven
mechanism
involving
triflate
moiety
abstraction
to
generate
reactive
cation.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(15), P. 4187 - 4193
Published: Jan. 1, 2024
Herein,
a
practical,
mild
and
convenient
strategy
was
disclosed
for
the
hydrogenation
of
alkenes
under
photocatalytic
conditions
through
HAT/protonation
process.
