Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(10), P. 3367 - 3367
Published: Jan. 1, 2023
Chiral
allylsilanes,
a
versatile
linchpin,
are
widely
used
in
the
area
of
asymmetric
synthesis.Therefore,
development
efficient
methodologies
for
preparation
enantioenriched
allylsilanes
has
attracted
great
attention.Significant
advances
have
been
made
catalytic
enantioselective
chiral
by
virtue
rapid
developments
catalysis.The
construction
and
their
synthetic
applications
summarized.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(7)
Published: Jan. 8, 2024
Abstract
A
Cu‐catalyzed
asymmetric
synthesis
of
silicon‐stereogenic
benzoxasiloles
has
been
realized
via
intramolecular
Si−O
coupling
[2‐(hydroxymethyl)phenyl]silanes.
Cu(I)/difluorphos
is
found
to
be
an
efficient
catalytic
system
for
enantioselective
Si−C
bond
cleavage
and
formation.
In
addition,
kinetic
resolution
racemic
substituted
[2‐(hydroxymethyl)phenyl]silanes
using
Cu(I)/
PyrOx
(pyridine‐oxazoline
ligands)
as
the
developed
afford
carbon‐
benzoxasiloles.
Ring‐opening
reactions
chiral
with
organolithiums
Grignard
reagents
yield
various
enantioenriched
functionalized
tetraorganosilanes.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(35), P. 7436 - 7441
Published: Aug. 26, 2024
Here,
we
report
the
development
and
application
of
a
novel
class
spirosilacycle-based
diphosphine
ligands
(SPOSiPs).
This
type
ligand
could
be
readily
prepared
in
two
steps
with
high
efficiency
starting
from
enantiopure
spirobiphenoxasilin-diol
(SPOSiOL).
According
to
structural
analysis
SPOSiP
its
PdCl2
complex,
SPOSiPs
possess
flexible
chiral
pocket
feature
rigid
configuration,
large
dihedral
angle,
long
P–P
distance,
P–M–P
bite
angle
their
metal
complexes.
The
potentials
asymmetric
catalysis
have
also
been
preliminarily
disclosed.
The Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
88(17), P. 12257 - 12264
Published: Aug. 14, 2023
A
transition-metal-free
hydrosilylation
of
allenes
is
reported
herein
by
using
commercially
available
lithium
triethylborohydride
(LiHBEt3)
as
the
catalyst.
Both
mono-
and
disubstituted
could
be
hydrosilylated
with
primary
or
secondary
silanes
effectively.
This
reaction
represents
an
environmental
economic
method
to
prepare
(E)-allylsilanes
in
good
yields
along
decent
selectivities.
Chinese Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
43(10), P. 3367 - 3367
Published: Jan. 1, 2023
Chiral
allylsilanes,
a
versatile
linchpin,
are
widely
used
in
the
area
of
asymmetric
synthesis.Therefore,
development
efficient
methodologies
for
preparation
enantioenriched
allylsilanes
has
attracted
great
attention.Significant
advances
have
been
made
catalytic
enantioselective
chiral
by
virtue
rapid
developments
catalysis.The
construction
and
their
synthetic
applications
summarized.
