Journal of Materials Chemistry C, Journal Year: 2024, Volume and Issue: 12(38), P. 15527 - 15534
Published: Jan. 1, 2024
A facile design strategy based on molecular engineering is proposed for the first time to achieve a series of PTD derivatives with tunable persistent RTP properties through substituent effects.
Language: Английский
Chemical Science, Journal Year: 2024, Volume and Issue: 15(12), P. 4222 - 4237
Published: Jan. 1, 2024
In this perspective, the progress in ion-regulated organic RTP materials and described roles of ions, including ion–π interactions, electrostatic coordinate have been summarized.
Language: Английский
Citations
21
Advanced Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 10, 2025
Abstract X‐ray induced photodynamic therapy (X‐PDT) leverages penetrating to generate singlet oxygen ( 1 O 2 ) for treating deep‐seated tumors. However, conventional X‐PDT typically relies on heavy metal inorganic scintillators and organic photosensitizers produce , which presents challenges related toxicity energy conversion efficiency. In this study, highly biocompatible phosphorescent nanoscintillators based hydrogen‐bonded frameworks (HOF) are designed engineered, termed BPT‐HOF@PEG, enhance in hepatocellular carcinoma (HCC) treatment. BPT‐HOF@PEG functions simultaneously as both scintillator photosensitizer, effectively absorbing transferring abundant . Both vitro vivo investigations demonstrate that internalized efficiently produces significant quantities of upon irradiation. Additionally, exposure directly inflicts DNA damage, the synergistic effects these mechanisms result pronounced cell death substantial tumor growth inhibition, with a inhibition rate up 90.4% assessments. RNA sequencing analyses reveal induces apoptosis Hepa1‐6 cells while inhibiting proliferation, culminating death. Therefore, work highlights considerable potential efficient HOF nanoscintillators‐based promising therapeutic approach HCC, providing effective alternative negligible patients unresectable
Language: Английский
Citations
2
Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)
Published: Aug. 22, 2024
Sustainable photoactivated room temperature phosphorescent materials exhibit great potential but are difficult to obtain. Here, we develop by covalently attaching lignin polylactic acid, where and acid the chromophore matrix, respectively. Initially phosphorescence of is quenched residual O2. However, switched on when oxygen consumed triplet excitons under continuous UV light irradiation. As such, lifetime increases from 3.0 ms 221.1 after 20 s activation. Interestingly, again being kept an atmosphere air for 2 h in absence irradiation due diffusion into materials. Using these properties, as-developed material successfully used as a smart anti-counterfeiting logo medicine bottle information recording. Convenient sustainable (RTP) wide ranging applications Here authors RTP acid.
Language: Английский
Citations
8
Angewandte Chemie, Journal Year: 2024, Volume and Issue: 136(26)
Published: April 19, 2024
Abstract Fluorescence sensing is crucial to studying biological processes and diagnosing diseases, especially in the second near‐infrared (NIR‐II) window with reduced background signals. However, it's still a great challenge construct “off‐on” sensors when wavelength extends into NIR‐II region obtain higher imaging contrast, mainly due difficult synthesis of spectral overlapped quencher. Here, we present new fluorescence quenching strategy, which utilizes steric hindrance quencher (SHQ) tune molecular packing state fluorophores suppress emission signal. Density functional theory (DFT) calculations further reveal that large SHQs can competitively pack prevent their self‐aggregation. Based on this mechanism, novel activatable method achieved via bio‐analyte responsive invalidation SHQ, namely Steric Hindrance Invalidation geNerated Emission (SHINE) strategy. As proof concept, ClO − ‐sensitive SHQ lead bright signal release epileptic mouse hippocampus under skull high photon scattering brain tissue, providing real‐time visualization generation process living mice.
Language: Английский
Citations
7
Chemical Science, Journal Year: 2024, Volume and Issue: 15(13), P. 4881 - 4889
Published: Jan. 1, 2024
Simultaneously enhancing the quantum yields and luminescence lifetimes of organic persistent room temperature phosphorescence (RTP) molecules is a priority in photonic area, but it remains formidable challenge. Here, an effective strategy was proposed to improve both efficiencies emission decay times for phosphorescent triphenylphosphine salts. This approach involves integrating electron donor unit into salt
Language: Английский
Citations
6
Chemical Communications, Journal Year: 2024, Volume and Issue: 60(70), P. 9328 - 9339
Published: Jan. 1, 2024
This article summarizes the potential of TPP salts in tuning RTP properties and their applications multi-level information encryption, high-level anticounterfeiting tags, X-ray scintillators.
Language: Английский
Citations
6
Chemical Science, Journal Year: 2024, Volume and Issue: 15(24), P. 9258 - 9265
Published: Jan. 1, 2024
A simple and facile surface coating protocol imparts visual room-temperature phosphorescence to flexible organic single crystals, allows their application in colour-tunable optical waveguiding anti-counterfeiting.
Language: Английский
Citations
5
Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(26)
Published: April 19, 2024
Fluorescence sensing is crucial to studying biological processes and diagnosing diseases, especially in the second near-infrared (NIR-II) window with reduced background signals. However, it's still a great challenge construct "off-on" sensors when wavelength extends into NIR-II region obtain higher imaging contrast, mainly due difficult synthesis of spectral overlapped quencher. Here, we present new fluorescence quenching strategy, which utilizes steric hindrance quencher (SHQ) tune molecular packing state fluorophores suppress emission signal. Density functional theory (DFT) calculations further reveal that large SHQs can competitively pack prevent their self-aggregation. Based on this mechanism, novel activatable method achieved via bio-analyte responsive invalidation SHQ, namely Steric Hindrance Invalidation geNerated Emission (SHINE) strategy. As proof concept, ClO
Language: Английский
Citations
4
Chemical Science, Journal Year: 2024, Volume and Issue: 15(21), P. 8052 - 8061
Published: Jan. 1, 2024
Room temperature phosphorescence (RTP) materials are increasingly recognized for their superior luminescent properties, which pivotal in applications such as anti-counterfeiting, information storage, and optoelectronics. Despite this, the sensitivity of most RTP systems to humidity presents a significant challenge achieving durable performance aqueous environments. This study proposes strategy enhance organic room-temperature through racemization. By incorporating external racemates various chiral phosphors-NDBD-Ph, NDBD-Ph-Ph, NDBD-CH3, NDBD-O-CH3-into polyacrylonitrile (PAN) matrix, we significantly properties (quantum yield, lifetime, afterglow-time) resultant films. enhancement can be attributed increased density racemic molecules matrix spin-orbit coupling (SOC), facilitating development long-lasting polymer system water. Notably, rac-NDBD-Ph@PAN film exhibits persistent bright turquoise afterglow, even after immersion water month. Furthermore, first time, achieved an enhanced green cyan response pH variations under both acidic alkaline conditions (pH = 2-12), with maximum emission intensity increasing up threefold. The remarkable stability, reversible characteristics, this offer promising potential dynamic encryption
Language: Английский
Citations
4
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153026 - 153026
Published: June 12, 2024
Language: Английский
Citations
4