Regenerative Biomimetic Photosynthesis by Covalent‐Organic Framework‐Based Nanobiohybrids DOI Open Access
Jueyi Xue, Juanfang Ruan, Karen Hakobyan

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Biomimetic photosynthesis, which leverages nanomaterials with light-responsive capabilities, represents an innovative approach for replicating natural photosynthetic processes green and sustainable energy conversion. In this study, a covalent-organic framework (COF)-based artificial photosynthesis system is realized through the co-assembly of adenosine triphosphate (ATP) synthase proton generator onto imine-based COF, RT-COF-1. This demonstrates ATP production rate 0.64 µmol per mg protein within 90 s light exposure and, first time, exhibites regenerative multiple on/off cycles. Furthermore, generated by facilitates biocoupling monosaccharides into disaccharides, confirming hybrid system's capability to convert solar chemical in form organic molecules. shows significant potential renewable bioenergy generation, offering precise reliable control over biochemical photosynthesis.

Language: Английский

Lateral nanoarchitectonics from nano to life: Ongoing challenge in interfacial chemical science DOI Creative Commons
Jingwen Song, Anna Jančík Procházková, Kohsaku Kawakami

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(45), P. 18715 - 18750

Published: Jan. 1, 2024

The construction of functional structures within a single plane still has lot challenges. This review article will help us find new groundbreaking directions in lateral nanoarchitectonics toward advanced material organization.

Language: Английский

Citations

6
Composite Nanoarchitectonics Towards Method for Everything in Materials Science DOI Creative Commons
Katsuhiko Ariga

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2024, Volume and Issue: 34(7), P. 2926 - 2947

Published: April 16, 2024

Abstract The characteristic feature of a biofunctional system is that components with various functions work together. These multi-components are not simply mixed together, but rationally arranged. fundamental technologies to do this in an artificial include the synthetic chemistry substances make component unit, science and techniques for assembling them, technology analyzing their nanoostructures. A new concept, nanoarchitectonics, can play role. Nanoarchitectonics post-nanotechnology concept involves building functional materials reflect nanostructures. In particular, approach combining multiple types create composite area where nanoarchitectonics be powerful tool. This review summarizes such examples related studies. presented areas catalyst & photocatalyst, energy, sensing environment, bio medical, other applications illustrate potential wide range applications. order show stages development, only state-of-the-art, also those successful developments existing research. Finally, summary brief discussion future challenges will given. applicable all aims establish ultimate methodology science.

Language: Английский

Citations

4
Interface‐Interactive Nanoarchitectonics: Solid and/or Liquid DOI Creative Commons
Katsuhiko Ariga

ChemPhysChem, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 23, 2024

Abstract The methodology of nanoarchitectonics is to construct functional materials using nanounits such as atoms, molecules, and nanoobjects, just like architecting buildings. Nanoarchitectonics pursues the ultimate concept science through integration related fields. In this review paper, under title interface‐interactive nanoarchitectonics, several examples structure fabrication function development at interfaces will be discussed, highlighting importance with nanoscale considerations. Two sections provide some solid liquid surfaces. interfacial environments, molecular structures can precisely observed analyzed theoretical calculations. Solid surfaces are a prime site for level. has potential pave way cutting‐edge functionality based on advanced observation analysis. Liquid more kinetic dynamic than interfaces, their high fluidity offers many possibilities fabrications by nanoarchitectonics. latter feature advantages in terms freedom interaction diversity components, therefore, may suitable environments functionalities. final section then discusses what needed future material creation

Language: Английский

Citations

3
Nanoarchitectonics for Biomedical Research: Post‐Nanotechnology Materials Approach for Bio‐Active Application DOI Creative Commons
Katsuhiko Ariga

Advanced NanoBiomed Research, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Nanoarchitectonics, as a post‐nanotechnology concept, represents methodology for the construction of functional materials employing atoms, molecules, and nanomaterials essential components. The overarching objective nanoarchitectonics is to develop systems comprising multiple units assembled in hierarchical manner, observed biological systems. Nevertheless, such challenging endeavor. It would be prudent, therefore, initially focus on development that interact with complex structures living organisms. Accordingly, this review article addresses topic nanoarchitecture it pertains biomedical applications. This examines current trends research presents examples studies support concept its applications fields. presented are follows: i) molecular developments, which mainly based design assembly; ii) material examples, using components; iii) porous materials, will summarized under heading pore‐engineered due their special structure. Finally, provides an overview these discusses future prospects.

Language: Английский

Citations

2
Molecular Insights into the Interactions Between Human Serum Albumin and Phospholipid Membranes DOI Creative Commons
Maciej Przybyłek, Piotr Bełdowski, Damian Ledziński

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(24), P. 11753 - 11753

Published: Dec. 17, 2024

In this study, molecular dynamics simulations were employed to analyze interactions between phospholipid membranes and human serum albumin (HSA) in the presence of mono- divalent cations. Two types membranes, composed dipalmitoyl phosphatidylcholine (DPPC) phosphatidylethanolamine (DPPE), utilized. The results revealed that both systems exhibited high stability. DPPE complexes displayed a greater affinity for compared DPPC. stability was attributed number ionic contacts hydrogen bonds. metal cations significantly influenced membrane’s capacity bind proteins. However, these effects varied depending on composition bilayer. studies confirmed relatively low ability DPPC potassium ions, as previously observed by others. Consequently, DPPC/HSA/K+ complex found be least stable among studied. While limited HSA domains I II, able interact with all protein. Both lipid bilayers substantial structural changes characteristic curvature induced HSA, which confirms formation strong capable influencing arrangement phospholipids.

Language: Английский

Citations

2
Exploring Excited‐State Intramolecular Proton‐Coupled Electron Transfer in Dinuclear Ir(III)‐Complex via Covalently Tagged Hydroquinone: Phototherapy Through Futile Redox Cycling DOI Creative Commons
Maniklal Shee,

Julia Schleisiek,

Nishith Maity

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Anticipating intramolecular excited-state proton-coupled electron transfer (PCET) process within dinuclear Ir2-photocatalytic system via the covalent linkage is seminal, yet challenging. Indeed, development of various complexes also promising for studying integral photophysics and facilitating applications in catalysis or biology. Herein, this study reports [Ir2(bis{imidazo-phenanthrolin-2-yl}-hydroquinone)(ppy)4]2+ (12+) complex by leveraging both ligand-centered redox property H-bonding exploring dual proton-transfer assisted PCET process. The vital role covalently placed hydroquinone bridged ligand investigated as electron-proton (ET-PT) mediator validated from triplet spin density plot. Moreover, bimolecular photoinduced ET reaction studied acetonitrile/water medium, forging lowest energy charge separated (3CSPhen-Im) state 12+ with methyl viologen favorably concerted-PCET pathway. result indicates strong donor-acceptors coupling, which limits recombination enhances catalytic efficiency. To showcase potential application, bioinspired PCET-based photocatalytic platform phototherapeutics, indicating significant mitochondrial localization leading to programmed cell death (apoptosis) through futile cycling. consequences effective internalization (via energy-dependent endocytosis), better safety profile, higher antiproliferative activity compared Cisplatin, explored 3D tumor spheroids, anticipates it be a lead compound.

Language: Английский

Citations

2
Nanoarchitectonics of Vesicle Microreactors for Oscillating ATP Synthesis and Hydrolysis DOI
Tonghui Wang, Jinbo Fei,

Fanchen Yu

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(45)

Published: July 23, 2024

Abstract We construct a compartmentalized nanoarchitecture to regulate bioenergy level. Glucose dehydrogenase, urease and nicotinamide adenine dinucleotide are encapsulated inside through liquid‐liquid phase separation. ATPase glucose transporter embedded in hybrid liposomes attached at the surface. is transported converted gluconic acid catalyzed by resulting an outward proton gradient drive for ATP synthesis. In parallel, catalyzes hydrolysis of urea generate ammonia, which leads inward hydrolysis. These processes lead change direction gradient, thus achieving artificial oscillation. Importantly, frequency amplitude oscillation can be programmed. The work explores nanoarchitectonics integrating multiple components realize precise

Language: Английский

Citations

1
Nanoarchitectonics of Vesicle Microreactors for Oscillating ATP Synthesis and Hydrolysis DOI
Tonghui Wang, Jinbo Fei,

Fanchen Yu

et al.

Angewandte Chemie, Journal Year: 2024, Volume and Issue: 136(45)

Published: July 23, 2024

Abstract We construct a compartmentalized nanoarchitecture to regulate bioenergy level. Glucose dehydrogenase, urease and nicotinamide adenine dinucleotide are encapsulated inside through liquid‐liquid phase separation. ATPase glucose transporter embedded in hybrid liposomes attached at the surface. is transported converted gluconic acid catalyzed by resulting an outward proton gradient drive for ATP synthesis. In parallel, catalyzes hydrolysis of urea generate ammonia, which leads inward hydrolysis. These processes lead change direction gradient, thus achieving artificial oscillation. Importantly, frequency amplitude oscillation can be programmed. The work explores nanoarchitectonics integrating multiple components realize precise

Language: Английский

Citations

1
Super-Resolution Microscopy as a Versatile Tool in Probing Molecular Assembly DOI Open Access
Nan Sun,

Shiwei Bai,

Luru Dai

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11497 - 11497

Published: Oct. 26, 2024

Molecular assembly is promising in the construction of advanced materials, obtaining structures with specific functions. In-depth investigation relationships between formation, dynamics, structure, and functionality molecular assemblies one greatest challenges nanotechnology chemistry, which essential rational design development functional materials for a variety applications. Super-resolution microscopy (SRM) has been used as versatile tool investigating elucidating individual its nanometric resolution, multicolor ability, minimal invasiveness, are also complementary to conventional optical or electronic techniques that provide direct observation. In this review, we will an overview representative studies utilize SRM probe assemblies, mainly focusing on imaging biomolecular (lipid-based, peptide-based, protein-based, DNA-based), organic–inorganic hybrid polymer assemblies. This review guidelines evaluation dynamics disassembly processes distinct dynamic behaviors, multicomponent through application these techniques. We believe inspire new ideas propel structural analyses promote exploitation new-generation materials.

Language: Английский

Citations

1
Regenerative Biomimetic Photosynthesis by Covalent‐Organic Framework‐Based Nanobiohybrids DOI Open Access
Jueyi Xue, Juanfang Ruan, Karen Hakobyan

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Biomimetic photosynthesis, which leverages nanomaterials with light-responsive capabilities, represents an innovative approach for replicating natural photosynthetic processes green and sustainable energy conversion. In this study, a covalent-organic framework (COF)-based artificial photosynthesis system is realized through the co-assembly of adenosine triphosphate (ATP) synthase proton generator onto imine-based COF, RT-COF-1. This demonstrates ATP production rate 0.64 µmol per mg protein within 90 s light exposure and, first time, exhibites regenerative multiple on/off cycles. Furthermore, generated by facilitates biocoupling monosaccharides into disaccharides, confirming hybrid system's capability to convert solar chemical in form organic molecules. shows significant potential renewable bioenergy generation, offering precise reliable control over biochemical photosynthesis.

Language: Английский

Citations

0