Talanta, Journal Year: 2023, Volume and Issue: 267, P. 125253 - 125253
Published: Sept. 27, 2023
Language: Английский
Plasmonics, Journal Year: 2023, Volume and Issue: 18(6), P. 2335 - 2345
Published: July 19, 2023
Language: Английский
Citations
64
ACS Nano, Journal Year: 2024, Volume and Issue: 18(3), P. 1757 - 1777
Published: Jan. 8, 2024
Many systems have been designed for the detection of SARS-CoV-2, which is virus that causes COVID-19. SARS-CoV-2 readily transmitted, resulting in rapid spread disease human populations. Frequent testing at point care (POC) a key aspect controlling outbreaks caused by and other emerging pathogens, as early identification infected individuals can then be followed appropriate measures isolation or treatment, maximizing chances recovery preventing infectious spread. Diagnostic tools used high-frequency should inexpensive, provide diagnostic response without sophisticated equipment, amenable to manufacturing on large scale. The application these devices enable large-scale data collection, help control viral transmission, prevent propagation. Here we review functional nanomaterial-based optical electrochemical biosensors accessible POC These incorporate nanomaterials coupled with paper-based analytical inexpensive substrates, traditional lateral flow technology (antigen antibody immunoassays), innovative biosensing methods. We critically discuss advantages disadvantages nanobiosensor-based approaches compared widely technologies such PCR, ELISA, LAMP. Moreover, delineate main technological, (bio)chemical, translational, regulatory challenges associated developing reliable biosensors, prevented their translation into clinic. Finally, highlight how nanobiosensors, given unique over existing tests, may future pandemics.
Language: Английский
Citations
36
Progress in Materials Science, Journal Year: 2024, Volume and Issue: 146, P. 101331 - 101331
Published: June 25, 2024
Borophene stands out uniquely among Xenes with its metallic character, Dirac nature, exceptional electron mobility, thermal conductivity, and Young's moduli—surpassing graphene. Invented in 2015, various methods, including atomic layer deposition, molecular beam epitaxy, chemical vapor have successfully been demonstrated to realize substrate-supported crystal growth. Top-down approaches like micromechanical, sonochemical, solvothermal modified hummer's techniques also employed. Thanks high electronic borophene serves as an active material for ultrafast sensing of light, gases, molecules, strain. Its behaviour, electrochemical activity, anti-corrosive nature make it ideal applications energy storage catalysis. It has proven effective electrocatalyst HER, OER, water splitting, CO2 reduction, NH3 reduction reactions. Beyond this, found utility bioimaging, biosensing, biomedical applications. A special emphasis will be given on the nanoarchitectonics i.e. doped borophene-based hybrids other 2D materials nanoparticles theoretical understanding these emerging systems gain more insights their structure properties, aiming manipulate tailored
Language: Английский
Citations
18
Nano Convergence, Journal Year: 2024, Volume and Issue: 11(1)
Published: Jan. 8, 2024
Abstract The COVID-19 outbreak caused by SARS-CoV-2 in late 2019 has spread rapidly across the world to form a global epidemic of respiratory infectious diseases. Increased investigations on diagnostic tools are currently implemented assist rapid identification virus because mass and diagnosis might be best way prevent virus. This critical review discusses detection principles, fabrication techniques, applications with three categories: nuclear acid augmentation test, immunoassay test biosensors. Special efforts were put enhancement nanomaterials biosensors for rapid, sensitive, low-cost diagnostics Future developments suggested regarding potential candidates hospitals, clinics laboratories control prevention large-scale epidemic. Graphical
Language: Английский
Citations
15
Bioengineering & Translational Medicine, Journal Year: 2022, Volume and Issue: 7(3)
Published: March 6, 2022
Abstract With the threat of increasing SARS‐CoV‐2 cases looming in front us and no effective safest vaccine available to curb this pandemic disease due its sprouting variants, many countries have undergone a lockdown 2.0 or planning 3.0. This has upstretched an unprecedented demand develop rapid, sensitive, highly selective diagnostic devices that can quickly detect coronavirus (COVID‐19). Traditional techniques like polymerase chain reaction proven be time‐inefficient, expensive, labor intensive, impracticable remote settings. shifts attention alternative biosensing successfully used sense COVID‐19 infection spread cases. Among these, nanomaterial‐based biosensors hold immense potential for rapid detection because their noninvasive susceptible, as well properties give real‐time results at economical cost. These mass understand progression better‐suited therapies. review provides overview existing diagnostics. Novel employing different mechanisms are also highlighted sections review. Practical tools required such make them reliable portable been discussed article. Finally, is concluded by presenting current challenges future perspectives
Language: Английский
Citations
33
Biosensors, Journal Year: 2022, Volume and Issue: 12(10), P. 862 - 862
Published: Oct. 12, 2022
The outbreak of Corona Virus Disease 2019 (COVID-19) has again emphasized the significance developing rapid and highly sensitive testing tools for quickly identifying infected patients. Although current reverse transcription polymerase chain reaction (RT-PCR) diagnostic techniques can satisfy required sensitivity specificity, inherent disadvantages with time-consuming, sophisticated equipment professional operators limit its application scopes. Compared traditional detection techniques, optical biosensors based on nanomaterials/nanostructures have received much interest in SARS-CoV-2 due to high sensitivity, accuracy, fast response. In this review, research progress diagnosis, including fluorescence biosensors, colorimetric Surface Enhancement Raman Scattering (SERS) Plasmon Resonance (SPR) was comprehensively summarized. Further, promising strategies improve are also explained. Optical not only realize but be applied judge infectiousness virus guide choice vaccines, showing enormous potential become point-of-care timely control pandemic.
Language: Английский
Citations
25
Biosensors, Journal Year: 2023, Volume and Issue: 13(2), P. 204 - 204
Published: Jan. 30, 2023
The COVID-19 pandemic revealed a pressing need for the development of sensitive and low-cost point-of-care sensors disease diagnosis. current standard care is quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). This method sensitive, but takes time, effort, requires specialized equipment reagents to be performed correctly. make it unsuitable widespread, rapid testing causes poor individual policy decision-making. Rapid antigen tests (RATs) are widely used alternative that provide results quickly have low sensitivity prone false negatives, particularly in cases with lower viral burden. Electrochemical shown much promise filling this technology gap, impedance spectroscopy specifically has exciting potential screening COVID-19. Due data-rich nature measurements at different frequencies, lends itself machine-leaning (ML) algorithms further data processing. review summarizes state spectroscopy-based detection SARS-CoV-2 virus. article also suggests future directions address technology’s limitations move forward prepare outbreaks.
Language: Английский
Citations
16
Talanta, Journal Year: 2023, Volume and Issue: 265, P. 124892 - 124892
Published: July 8, 2023
Language: Английский
Citations
16
Optical Materials, Journal Year: 2024, Volume and Issue: 149, P. 114977 - 114977
Published: Feb. 4, 2024
Language: Английский
Citations
5
Biosensors, Journal Year: 2022, Volume and Issue: 12(10), P. 898 - 898
Published: Oct. 20, 2022
The COVID-19 pandemic has severely impacted normal human life worldwide. Due to its rapid community spread and high mortality statistics, the development of prompt diagnostic tests for a massive number samples is essential. Currently used traditional methods are often expensive, time-consuming, laboratory-based, unable handle large specimens in resource-limited settings. Because contagiousness, efficient identification SARS-CoV-2 carriers crucial. As advantages adopting biosensors diagnosis increase, this narrative review summarizes recent advances respective reasons consider applying biosensors. Biosensors most sensitive, specific, rapid, user-friendly tools having potential deliver point-of-care diagnostics beyond standards. This provides brief introduction conventional their disadvantages. It also discusses pathogenesis COVID-19, biomarkers, using biosensor technology. current advancements biosensing technologies, from academic research commercial achievements, have been emphasized publications. We covered wide range topics, including biomarker detection, viral genomes, proteins, immune responses infection, other proinflammatory biomolecules. Major challenges prospects future application settings highlighted.
Language: Английский
Citations
19