Frontiers in Endocrinology,
Journal Year:
2023,
Volume and Issue:
14
Published: Aug. 17, 2023
Diabetic
foot
ulcer
(DFU)
is
a
major
complication
of
diabetes
and
associated
with
high
risk
lower
limb
amputation
mortality.
During
their
lifetime,
19%–34%
patients
can
develop
DFU.
It
estimated
that
61%
DFU
become
infected
15%
those
require
amputation.
Furthermore,
developing
increases
the
mortality
by
50%–68%
at
5
years,
higher
than
some
cancers.
Current
standard
management
includes
surgical
debridement,
use
topical
dressings
wound
decompression,
vascular
assessment,
glycemic
control.
Among
these
methods,
local
treatment
builds
protective
physical
barrier,
maintains
moist
environment,
drains
exudate
from
wounds.
This
review
summarizes
development,
pathophysiology,
healing
mechanisms
The
latest
research
progress
main
application
in
laboratory
clinical
stage
are
also
summarized.
discussed
this
include
traditional
(gauze,
oil
yarn,
Chinese
medicine,
others),
basic
(hydrogel,
hydrocolloid,
sponge,
foam,
film
agents,
bacteriostatic
dressings,
composite
(collagen,
nanomaterials,
chitosan
bioactive
(scaffold
stem
cells,
decellularized
matrix,
autologous
platelet
enrichment
plasma,
modern
technology
(3D
bioprinting,
photothermal
effects,
bioelectric
microneedle
smart
bandages,
orthopedic
prosthetics
regenerative
medicine).
dressing
challenges
limitations
purpose
to
help
readers
understand
pathogenesis
mechanism
DFU,
physicians
select
correctly,
provide
an
updated
overview
potential
biomaterials
devices
management,
ideas
for
further
exploration
development
dressings.
Proper
promote
healing,
reduce
cost
treating
patient
pain.
Journal of Clinical Cardiology,
Journal Year:
2024,
Volume and Issue:
5(1), P. 6 - 29
Published: Jan. 5, 2024
Cardiovascular
diseases
(CVDs)
remain
a
leading
cause
of
morbidity
and
mortality
worldwide.
Effective
prevention
management
strategies
are
essential
to
reduce
the
burden
CVDs.
This
review
summarizes
recent
advances
in
In
terms
prevention,
lifestyle
modifications,
such
as
diet,
exercise,
smoking
cessation,
important
strategies.
Pharmacological
interventions,
including
statins,
antiplatelet
agents,
antihypertensive
medications,
have
also
shown
benefits.
Innovative
approaches,
genetic
testing
risk
stratification,
targeted
strategies,
use
mobile
health
technology,
being
explored.
management,
acute
reperfusion
therapy
for
myocardial
infarction,
heart
failure
stroke
improved
outcomes.
Chronic
medical
failure,
arrhythmia
device
precision
medicine
personalized
treatment,
artificial
intelligence
diagnosis
traditional
Chinese
regenerative
medicine,
investigated.
While
CVDs
promising,
challenges
implementing
these
cost-effectiveness,
access
care,
resistance
change
clinical
practice.
Continued
research
innovation
improve
patient
Biomedical Materials,
Journal Year:
2024,
Volume and Issue:
19(5), P. 052001 - 052001
Published: July 8, 2024
Abstract
Wound
healing
is
a
critical
but
complex
biological
process
of
skin
tissue
repair
and
regeneration
resulting
from
various
systems
working
together
at
the
cellular
molecular
levels.
Quick
wound
problems
associated
with
traditional
techniques
are
being
overcome
multifunctional
materials.
Over
time,
this
research
area
has
drawn
significant
attention.
Metal-organic
frameworks
(MOFs),
owning
to
their
peculiar
physicochemical
characteristics,
now
considered
promising
class
well-suited
porous
materials
for
in
addition
other
applications.
This
detailed
literature
review
provides
an
overview
latest
developments
MOFs
We
have
discussed
synthesis,
essential
biomedical
properties,
wound-healing
mechanism,
MOF-based
dressing
materials,
The
possible
major
challenges
limitations
been
discussed,
along
conclusions
future
perspectives.
addresses
MOFs-based
several
angles
covers
most
current
subject.
readers
may
discover
how
advanced
discipline
by
producing
more
inventive,
useful,
successful
dressings.
It
influences
development
generations
biomaterials
wounds.
