Neoangiogenetic potential of Nd:YAG 1064 nm photobiomodulation in non-surgical healing of trauma induced periapical bone defects: a clinicalprospective pilot study

Lasers in Medical Science, Journal Year: 2025, Volume and Issue: 40(1)

Published: Feb. 19, 2025

Language: Английский

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Enhanced Photothermal Tumor Ablation Using Polypyrrole‐Gold Nanocomposites Activated by Polarized Polychromatic Low‐Energy Light: An In Vivo Study

Journal of Biophotonics, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

ABSTRACT Photothermal therapy (PTT) offers a minimally invasive approach for cancer treatment, using light energy to selectively heat and destroy cells. Success in PTT depends on efficient, stable, biocompatible photothermal agents. This study investigates polypyrrole@gold nanocomposites (PPy@Au NCs) as agents combined with polarized polychromatic low‐energy (PPLEL) target tumors limit disease progression. In vivo experiments Ehrlich carcinoma‐bearing female Swiss albino mice demonstrated that PPy@Au NCs accumulated tumor tissue and, when activated by PPLEL, generated sufficient effective ablation. enhanced treatment efficacy presented cost‐effective solution due the affordability of both nanocomposite source. Histopathological analysis confirmed significant reduction, suggesting this synergistic combination promising strategy. Findings support further research potential clinical applications therapy.

Language: Английский

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Enhancing Sickle Cell Leg Ulcer Healing with Combined Photodynamic and Photobiomodulation Therapies: a pilot experience

Journal of Tissue Viability, Journal Year: 2025, Volume and Issue: 34(2), P. 100879 - 100879

Published: Feb. 26, 2025

Language: Английский

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Photobiomodulation therapy

JADA Foundational Science, Journal Year: 2025, Volume and Issue: 4, P. 100045 - 100045

Published: Jan. 1, 2025

Language: Английский

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Efficacy of photobiomodulation therapy on pain perception reduction associated with dental anesthetic infiltration injection: A systematic review and meta‐analysis

Photochemistry and Photobiology, Journal Year: 2024, Volume and Issue: unknown

Published: June 6, 2024

Abstract Dental anesthetic injections, a common source of patient discomfort, often deter individuals from seeking dental care. Recently, there has been growing focus on photobiomodulation therapy (PBMT) and its potential role in pain reduction. This systematic review explored the efficacy PBMT alleviating associated with infiltration injections. A literature search different databases was performed up to December, 2023 using specific strategy find eligible studies that assessed impact during local anesthesia Data extraction done based inclusion/exclusion criteria. total 13 studies, involving 972 patients were included. The employed various parameters, including wavelengths, energy densities. Meta‐analyses revealed significant reduction compared controls (MD = −0.90, 95% CI: −1.36 −0.44, p 0.0001), notable heterogeneity ( I 2 91.79%). Stratified analyses by age demonstrated consistent both adults −0.59, −1.11 −0.08, < 0.0001) children 0.025). In conclusion, it seems infrared diode lasers can effectively reduce injection pediatric adult populations. Further research should optimizing parameters for enhanced management procedures.

Language: Английский

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Effectiveness of the Association of Fibrin Scaffolds, Nanohydroxyapatite, and Photobiomodulation with Simultaneous Low-Level Red and Infrared Lasers in Bone Repair

Materials, Journal Year: 2024, Volume and Issue: 17(17), P. 4351 - 4351

Published: Sept. 3, 2024

Biomaterials and biopharmaceuticals for correcting large bone defects are a potential area of translational science. A new bioproduct, purified from snake venom fibrinogen buffalo blood, aroused interest in the repair venous ulcers. Expanding uses, it has also been used to form biocomplexes combination with grafts, associated physical therapies or alone. The aim this preclinical study was evaluate low-level laser photobiomodulation (PBM) critical calvaria rats filled nanohydroxyapatite (NH) heterologous fibrin biopolymer (HFB). Sixty animals were used, divided into six groups (n = 10 each): G1 (NH); G2 (HFB); G3 (NH + HFB); G4 PBM); G5 (HFB G6 HFB PBM). PBM simultaneously red (R) infrared (IR) light emission, applied intraoperatively twice week, until end experiment at 42 days. Microtomography, formation can be seen initially margins defect, more evident G5. Microscopically, demonstrated immature disorganized trabeculation 14 days, remnants grafting materials. At percentage formed higher all groups, especially (HFB, 45.4 ± 3.82), collagen fibers degree maturation yellowish-green color birefringence analysis Picrosirius-red. Therefore, is concluded that showed greater effectiveness process presents future clinical studies.

Language: Английский

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Efficacy of photobiomodulation therapy on Bell’s palsy symptoms: a systematic review

Lasers in Medical Science, Journal Year: 2024, Volume and Issue: 39(1)

Published: Dec. 4, 2024

Language: Английский

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Efficacy of Low-level Laser Therapy and Light-emitting Diode Therapy in Modulating Osteoclastic Activity on Titanium Disk: An In Vitro Study

International Journal of Prosthodontics and Restorative Dentistry, Journal Year: 2024, Volume and Issue: 14(4), P. 202 - 207

Published: Dec. 30, 2024

Language: Английский

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The effect of different intracanal irrigants on the push-out bond strength of dentin in damaged anterior primary teeth

Journal of Medicine and Life, Journal Year: 2024, Volume and Issue: 17(5), P. 536 - 542

Published: May 1, 2024

This experimental study investigated the effect of different intracanal irrigants on push-out bond strength dentin in damaged anterior primary teeth. The crowns 90 teeth were sectioned horizontally, 1 mm above cementoenamel junction (CEJ). Following canal preparation with K-files, all groups except negative control received normal saline irrigation. Canals then irrigated either 3% or 5.25% sodium hypochlorite (NaOCl), 2% 0.2% chlorhexidine (CHX) solution (except and positive controls). roots filled Metapex material covered a calcium hydroxide liner. In root canals, was applied by self-etching light-cured for 20 seconds before canals restored incrementally composite. Stereomicroscopes used to assess failure patterns. Push-out strengths (MPa ± SD) were: NaOCl (16.92 5.78), (8.96 3.55), CHX (14.76 5.56), (7.76 2.93). Significant differences seen across regarding sections (P <0.001). most frequent failures adhesive cohesive. increased compared controls. Compared controls, both significantly non-vital

Language: Английский

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Application of botulinum toxin A in tissue repair and regeneration

Toxicon, Journal Year: 2024, Volume and Issue: 252, P. 108172 - 108172

Published: Nov. 13, 2024

Language: Английский

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