Tetrahedron, Journal Year: 2024, Volume and Issue: 154, P. 133891 - 133891
Published: Feb. 15, 2024
Language: Английский
Tetrahedron, Journal Year: 2024, Volume and Issue: 154, P. 133891 - 133891
Published: Feb. 15, 2024
Language: Английский
Chemical Reviews, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 13, 2024
Hypervalent iodine(III) compounds have found wide application in modern organic chemistry as environmentally friendly reagents and catalysts. iodine are commonly used synthetically important halogenations, oxidations, aminations, heterocyclizations, various oxidative functionalizations of substrates. Iodonium salts arylating reagents, while iodonium ylides imides excellent carbene nitrene precursors. Various derivatives benziodoxoles, such azidobenziodoxoles, trifluoromethylbenziodoxoles, alkynylbenziodoxoles, alkenylbenziodoxoles group transfer the presence transition metal catalysts, under metal-free conditions, or using photocatalysts photoirradiation conditions. Development hypervalent catalytic systems discovery highly enantioselective reactions chiral represent a particularly recent achievement field chemistry. Chemical transformations promoted by many cases unique cannot be performed any other common, non-iodine-based reagent. This review covers literature published mainly last 7-8 years, between 2016 2024.
Language: Английский
Citations
34Bioorganic & Medicinal Chemistry Letters, Journal Year: 2025, Volume and Issue: 119, P. 130096 - 130096
Published: Jan. 9, 2025
Language: Английский
Citations
2Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(5), P. 1112 - 1116
Published: Jan. 1, 2022
The direct synthesis of isocoumarin skeletons has been realized through the Rh( iii )-catalyzed [3 + 3] annulation sulfoxonium ylides and iodonium under mild conditions.
Language: Английский
Citations
34Organic Letters, Journal Year: 2024, Volume and Issue: 26(24), P. 5136 - 5140
Published: June 7, 2024
Herein, we report a rhodium-catalyzed C–H activation/[4+2] cyclization reaction between α,β-unsaturated amides and iodonium ylides for the synthesis of novel 7,8-dihydroquinoline-2,5-diones analogues. This protocol provides series pyridones fused with saturated cycles good functional group compatibility, water air tolerance, to excellent yields under mild green conditions. Additionally, scale-up can be smoothly performed as low 0.25 mol % catalyst loading. Recycling experiments different transformation were also carried out demonstrate potential synthetic utility this protocol.
Language: Английский
Citations
9The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(14), P. 10180 - 10196
Published: July 4, 2024
Presented herein are novel syntheses of CF
Language: Английский
Citations
9Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 21(1), P. 24 - 38
Published: Nov. 23, 2022
The metal-catalyzed successive activation and functionalization of arene/heteroarene is one the most fundamental transformations in organic synthesis leads to privileged scaffolds natural products, pharmaceuticals, agrochemicals, fine chemicals. Particularly, transition-metal-catalyzed C-H arenes with carbene precursors via metal migratory insertion has been well studied. As a result, diverse have evaluated, such as diazo compounds, sulfoxonium ylides, triazoles, etc. In addition, there significant developments use iodonium ylides recent years, these reactions proceed high efficiencies selectivities. This review provides comprehensive overview functionalizations, including scope, limitations, their potential synthetic applications.
Language: Английский
Citations
29Chemical Communications, Journal Year: 2022, Volume and Issue: 58(97), P. 13483 - 13486
Published: Jan. 1, 2022
A straightforward approach to synthesise isocoumarins via Rh(III)-catalyzed C-H/C-C bond activation/annulation cascade of enaminones and iodonium ylides has been explored. The established protocol is characterized by an exceedingly simple reaction system, high regioselectivity good functional group tolerance. Moreover, this strategy may provide a new route cleavage the C(sp2)-C(O) unstrained ketones.
Language: Английский
Citations
25New Journal of Chemistry, Journal Year: 2023, Volume and Issue: 47(26), P. 12274 - 12278
Published: Jan. 1, 2023
A wide variety of isocoumarin derivatives are easily constructed via a Rh( iii )-catalyzed C–H bond activation/annulation cascade reaction.
Language: Английский
Citations
15The Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 87(12), P. 8142 - 8150
Published: June 8, 2022
The rhodium(III)-catalyzed C–H activation followed by intramolecular annulation reactions between arylhydrazines and iodonium ylides under suitable conditions has been described. Tetrahydrocarbazol-4-ones are readily achieved with moderate to excellent yields. synthetic protocol features a wide range of substrates high functional group tolerance. gram-scale reaction derivatization the product demonstrate practicality utilization this method.
Language: Английский
Citations
20Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
β-Enaminone transformation strategies are widely employed in the synthesis of numerous biologically active drugs and natural products, highlighting their significance medicinal chemistry.
Language: Английский
Citations
5