Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Catalysis Today, Journal Year: 2024, Volume and Issue: 443, P. 114969 - 114969
Published: Aug. 6, 2024
Language: Английский
Citations
6Catalysts, Journal Year: 2025, Volume and Issue: 15(1), P. 78 - 78
Published: Jan. 15, 2025
In this study, the palladium-catalyzed aminocarbonylation of 1-iodoisoquinoline was accomplished in presence various amines. While reactions with simple primary and secondary amines were carried out by using well-known Pd(OAc)2/PPh3 catalyst, application lower basicity (e.g., aromatic amines) or more difficult structures amino acid methyl esters, nortropine, diethyl (α-aminobenzyl)phosphonate) required use bidentate XantPhos ligand to achieve complete conversion short reaction time (2–8 h). way, several valuable isoquinoline-1-carboxamides synthesized chemoselective carbonylation isolated good high yields (55–89%). Furthermore, model compound also investigated three biomass-derived solvents (GVL, ethyl levulinate, 2-MeTHF). After comparing outcome DMF above green solvents, similar reactivity observed, justifying that they could be considered a feasible alternative medium.
Language: Английский
Citations
0Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: May 12, 2025
We developed a stereoselective synthesis strategy for α-fluoroacrylate-substituted β-lactams, utilizing an innovative acid-base synergistic regulation approach. This method employs dioxane-mediated microreaction environment to spatially separate acidic and alkaline reagents, enabling precise control over cyclization fluorination processes. enhances catalytic efficiency addresses challenges in Pd-catalyzed reactions, offering new paradigm synthesizing fluorinated drug molecules amid complexities.
Language: Английский
Citations
0Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
1ChemPlusChem, Journal Year: 2024, Volume and Issue: 89(11)
Published: July 9, 2024
Abstract Cyrene, a renewable, non‐toxic substance having negligible vapor pressure, even at high temperatures, was proposed as reaction medium for homogeneous Pd‐catalyzed Heck‐coupling reactions. It first characterized by its temperature‐dependent physicochemical properties, i. e., density, surface tension, heat capacity, and viscosity, the key parameters of process chemistry. Its refractive indices in function temperature were also determined. Hereafter, effect (Pd source, nature base, water content mixture, leaving group (−I, −Br, −Cl, −OTf aromatic substrates) on investigated using iodobenzene styrene model substrates. Subsequently, 4‐substituted derivatives applied to investigate electronic efficiency functional tolerance. To demonstrate applicability system, thirteen stilbene isolated with good yields purity (>95 %) 0.2 mol % Pd, 1.5 eq. Et 3 N 1 mL Cyrene 2 h 100 °C.
Language: Английский
Citations
1Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
1Journal of Environmental Sciences, Journal Year: 2024, Volume and Issue: unknown
Published: June 1, 2024
Language: Английский
Citations
0Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(17), P. 4740 - 4747
Published: Jan. 1, 2024
The Reppe sulfonylation reaction has remained substantially underexplored. We present a novel method for involving SO 2 insertion, remarkably without the need metal catalysts, instead utilizing Brønsted bases as catalysts.
Language: Английский
Citations
0Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
0Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
0