Base-controlled selective cleavage of the C–F bond of difluorocarbene for the divergent assembly of indolizines
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(15), P. 4214 - 4218
Published: Jan. 1, 2024
A
[3
+
1
1]
cascade
annulation
reaction
for
the
divergent
construction
of
trisubstituted
indolizines
using
sulfoxonium
ylides,
BrCF
2
CO
Me
and
pyridinium
salts
as
readily
available
substrates
has
been
developed.
Language: Английский
Synthesis of β,β-Dithioketones by Merging C–C and C–S Bond Cleavage in [1 + 1 + 1 + 1 + 1 + 1] Annulation
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(20), P. 4340 - 4345
Published: May 14, 2024
An
unconventional
[1
+
1
1]
annulation
process
was
developed
for
the
construction
of
β,β-dithioketones
by
merging
C–C
and
C–S
bond
cleavage.
In
this
reaction,
rongalite
concurrently
served
as
triple
C1
units,
dual
sulfur(II)
synthons,
a
reductant
first
time.
Mechanism
investigation
indicated
that
reaction
involved
self-mediated
valence
state
change
rongalite.
By
performing
step-economical
method,
challenging
C5-substituted
1,3-dithiane
can
be
achieved
under
mild
simple
conditions.
Language: Английский
Difluorocarbene-Enabled Trifluoromethylation and Cyclization for the Synthesis of 3-(Trifluoromethyl)-4H-pyrans
Organic Letters,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 27, 2024
A
three-component
annulation
reaction
and
trifluoromethylation
for
the
construction
of
3-(trifluoromethyl)-4
Language: Английский
Iron‐Mediated Desulfonylative Cross‐Electrophile Couplings of Heteroaryl Sulfones with Thiosulfonates for Efficient Synthesis of Heteroaryl Sulfides
Yuan He,
No information about this author
Jie Pan,
No information about this author
Ying Yan
No information about this author
et al.
Chinese Journal of Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: May 28, 2025
Comprehensive
Summary
A
desulfonylative
thiolation
between
heteroaryl
sulfones
and
thiosulfonates
for
the
efficient
synthesis
of
sulfides
was
developed.
The
cross‐electrophile
couplings
proceeded
effectively
via
old
C–SO
2
bond
cleavage
new
C–S
formation
in
presence
cheapest
widely
available
iron
powder
as
mediator
under
transition
metal
catalyst‐free
conditions,
leading
to
a
wide
array
derived
from
benzo[
d
]thiazole,
]oxazole,
thiazole,
1,3,4‐thiadiazole,
1
H
‐tetrazole
modest
excellent
yields.
In
addition,
reaction
exhibited
good
functional
group
compatibility,
protocol
could
also
be
applicable
use
selenosulfonate
substrate
subjected
scale‐up
with
equal
ease.
Notably,
unreacted
readily
recovered
after
by
resorting
attracting
property
magnetic
stir
bar
iron.
Language: Английский
Intramolecular/Intermolecular Sequential Cyclization Accompanied by Double C–F Bond Cleavage: Access to Tricyclic Fluorine-Containing Pyrano[3,2-c]chromenes
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(22), P. 16553 - 16563
Published: Oct. 28, 2024
Defluorinative
cyclization
of
CF
Language: Английский