Scouting the efficacy of targeted gold nanoparticles in the landscape of cancer therapy DOI
Mahak Fatima, Garima Gupta,

Swaranjeet Arora

et al.

European Polymer Journal, Journal Year: 2024, Volume and Issue: 209, P. 112924 - 112924

Published: March 11, 2024

Language: Английский

Nanoparticles in cancer theragnostic and drug delivery: A comprehensive review DOI Creative Commons

Alshayma N. Al-Thani,

Asma Ghafoor Jan,

Mohamed Abbas

et al.

Life Sciences, Journal Year: 2024, Volume and Issue: 352, P. 122899 - 122899

Published: July 9, 2024

This comprehensive review provides an in-depth analysis of how nanotechnology has revolutionized cancer theragnostic, which combines diagnostic and therapeutic methods to customize treatment. The study examines the unique attributes, uses, difficulties linked different types nanoparticles, including gold, iron oxide, silica, Quantum dots, Carbon nanotubes, liposomes, in context In addition, paper progression nanotheranostics, emphasizing its uses precise medication administration, photothermal therapy, sophisticated such as MRI, CT, fluorescence imaging. Moreover, article highlights capacity nanoparticles improve effectiveness drugs, reduce overall toxicity body, open up new possibilities for treating by releasing drugs a controlled manner targeting specific areas. Furthermore, it tackles concerns regarding compatibility their potential harmful effects, significance continuous nanotherapeutic use medical treatments. finishes outlining future applications predictive oncology customized medicine.

Language: Английский

Citations

67

Chitosan-based nanosystems for cancer diagnosis and therapy: Stimuli-responsive, immune response, and clinical studies DOI
Farnaz Dabbagh Moghaddam, Ehsan Nazarzadeh Zare‬,

Mahnaz Hassanpour

et al.

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 330, P. 121839 - 121839

Published: Jan. 20, 2024

Language: Английский

Citations

30

Revolutionary Point‐of‐Care Wearable Diagnostics for Early Disease Detection and Biomarker Discovery through Intelligent Technologies DOI Creative Commons
Fatemeh Haghayegh,

Alireza Norouziazad,

Elnaz Haghani

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: July 3, 2024

Early-stage disease detection, particularly in Point-Of-Care (POC) wearable formats, assumes pivotal role advancing healthcare services and precision-medicine. Public benefits of early detection extend beyond cost-effectively promoting outcomes, to also include reducing the risk comorbid diseases. Technological advancements enabling POC biomarker recognition empower discovery new markers for various health conditions. Integration wearables with intelligent frameworks represents ground-breaking innovations automation operations, conducting advanced large-scale data analysis, generating predictive models, facilitating remote guided clinical decision-making. These substantially alleviate socioeconomic burdens, creating a paradigm shift diagnostics, revolutionizing medical assessments technology development. This review explores critical topics recent progress development 1) systems solutions physiological monitoring, as well 2) discussing current trends adoption smart technologies within settings developing biological assays, ultimately 3) exploring utilities platforms discovery. Additionally, translation from research labs broader applications. It addresses associated risks, biases, challenges widespread Artificial Intelligence (AI) integration diagnostics systems, while systematically outlining potential prospects, challenges, opportunities.

Language: Английский

Citations

24

Nanoparticles in cancer diagnosis and treatment: Progress, challenges, and opportunities DOI Creative Commons
Niloufar Rashidi, Majid Davidson, Vasso Apostolopoulos

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 95, P. 105599 - 105599

Published: March 26, 2024

Despite considerable progress in patient care, the global incidence of various cancer types continues to rise. Developing safer and more efficient anti-cancer treatment approaches are great interest. In recent decades, nanotechnology has emerged as a promising innovative medical approach for diagnosis treatment. However, nanomedicine advances, it is important understand address challenges. Herein, we identify gaps current understanding effectiveness on clinical outcomes provide an outlook improved application medicine. We discuss use different nanoparticles therapy impact efficiency existing treatments, such chemotherapeutic, anti-angiogenic, immunotherapeutic drugs, radiotherapy. Additionally, update status trials nanoparticle-based treatments provided.

Language: Английский

Citations

21

Emerging Multifunctional Carbon‐Nanomaterial‐Based Biosensors for Cancer Diagnosis DOI Creative Commons

Jolitta Sheri John Britto,

Xinwei Guan, Thi Kim Anh Tran

et al.

Small Science, Journal Year: 2024, Volume and Issue: 4(3)

Published: Jan. 22, 2024

Despite significant advancements in medical technology, cancer remains the world's second‐leading cause of death, largely attributed to late‐stage diagnoses. While traditional detection methodologies offer foundational insights, they often lack specificity, affordability, and sensitivity for early‐stage identification. In this context, development biosensors offers a distinct possibility precise rapid identification biomarkers. Carbon nanomaterials, including graphene, carbon nitride, quantum dots, other carbon‐based nanostructures, are highly promising detection. Their simplicity, high sensitivity, cost‐effectiveness contribute their potential field. This review aims elucidate emerging carbon‐nanomaterial‐based early diagnosis. The relevance various biosensor mechanisms performance physicochemical properties nanomaterials is discussed depth, focusing on demonstrating broad creating biosensors. Diverse techniques, such as electrochemical, fluorescence, surface plasmon resonance, electrochemiluminescence, quartz crystal microbalance, emphasized At last, summary existing challenges future outlook field elaborated.

Language: Английский

Citations

20

Advancing cancer diagnosis and treatment: integrating image analysis and AI algorithms for enhanced clinical practice DOI Creative Commons
Hamid Reza Saeidnia, Faezeh Firuzpour, Marcin Kozak

et al.

Artificial Intelligence Review, Journal Year: 2025, Volume and Issue: 58(4)

Published: Jan. 25, 2025

Language: Английский

Citations

4

Recent Trends in Biosensing and Diagnostic Methods for Novel Cancer Biomarkers DOI Creative Commons
Jagadeeswara Rao Bommi, Shekher Kummari,

Kavitha Lakavath

et al.

Biosensors, Journal Year: 2023, Volume and Issue: 13(3), P. 398 - 398

Published: March 18, 2023

Cancer is one of the major public health issues in world. It has become second leading cause death, with approximately 75% cancer deaths transpiring low- or middle-income countries. causes a heavy global economic cost estimated at more than trillion dollars per year. The most common cancers are breast, colon, rectum, prostate, and lung cancers. Many these can be treated effectively cured if detected primary stage. Nowadays, around 50% late stages, to serious complications death. Early diagnosis diseases substantially increases efficient treatment high chances survival. Biosensors potential screening methodologies useful early biomarkers. This review summarizes recent findings about novel biomarkers their advantages over traditional biomarkers, biosensing diagnostic methods for them; thus, this may helpful recognition monitoring response various human

Language: Английский

Citations

30

Current research status of tumor cell biomarker detection DOI Creative Commons

Liying Jiang,

Xinyi Lin, Fenghua Chen

et al.

Microsystems & Nanoengineering, Journal Year: 2023, Volume and Issue: 9(1)

Published: Oct. 5, 2023

Abstract With the annual increases in morbidity and mortality rates of tumors, use biomarkers for early diagnosis real-time monitoring tumor cells is great importance. Biomarkers used cell detection body fluids include circulating cells, nucleic acids, protein markers, extracellular vesicles. Among them, DNA, exosomes have high potential prediction, diagnosis, prognosis diseases due to large amount valuable information on characteristics evolution; addition, situ telomerase miRNA living has been topic extensive research understand development real time. Various techniques, such as enzyme-linked immunosorbent assays, immunoblotting, mass spectrometry, widely these markers. markers based electrochemical biosensors fluorescence signal analysis highly preferred because its sensitivity, rapid portable operation. Herein, we summarize recent progress using biosensors, outline current status discuss technical challenges their practical clinical application provide a reference new marker methods.

Language: Английский

Citations

24

Advances in Non-Small Cell Lung Cancer: Current Insights and Future Directions DOI Open Access
Pankaj Garg, Sulabh Singhal, Prakash Kulkarni

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(14), P. 4189 - 4189

Published: July 18, 2024

The leading cause of cancer deaths worldwide is attributed to non-small cell lung (NSCLC), necessitating a continual focus on improving the diagnosis and treatment this disease. In review, latest breakthroughs emerging trends in managing NSCLC are highlighted. Major advancements diagnostic methods, including better imaging technologies utilization molecular biomarkers, discussed. These have greatly enhanced early detection personalized plans. Significant improvements patient outcomes been achieved by new targeted therapies immunotherapies, providing hope for individuals with advanced NSCLC. This review discusses persistent challenges accessing treatments their associated costs despite recent progress. Promising research into therapies, such as CAR-T therapy oncolytic viruses, which could further revolutionize treatment, also aims inform inspire continued efforts improve patients globally, offering comprehensive overview current state future possibilities.

Language: Английский

Citations

11

Precise diagnosis of tumor cells and hemocytes using ultrasensitive, stable, selective cuprous oxide composite SERS bioprobes assisted with high-efficiency separation microfluidic chips DOI

Yujiao Xie,

Lei Xu, J.Y. Zhang

et al.

Materials Horizons, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

In this study, we reported a flower-like Cu 2 O@Ag SERS substrate for distinguish three types of cancer cells from white blood by using machine learning-assisted LDA, after separating samples via microfluidic chip.

Language: Английский

Citations

11