Western and ketogenic diets in neurological disorders: can you tell the difference? DOI
Karl J. Habashy,

Fatima Ahmad,

Stanley Ibeh

et al.

Nutrition Reviews, Journal Year: 2022, Volume and Issue: 80(8), P. 1927 - 1941

Published: Jan. 14, 2022

The prevalence of obesity tripled worldwide between 1975 and 2016, it is projected that half the US population will be overweight by 2030. pandemic attributed, in part, to increasing consumption high-fat, high-carbohydrate Western diet, which predisposes development metabolic syndrome correlates with decreased cognitive performance. In contrast, low-carbohydrate ketogenic diet has potential therapeutic roles been used manage intractable seizures since early 1920s. brain accounts for 25% total body glucose metabolism and, as a result, especially susceptible changes types nutrients consumed. Here, we discuss principles focus on distinct effects diets progression neurological diseases such epilepsy, Parkinson's disease, Alzheimer's traumatic injury, highlighting need further explore importance standardizing dietary formulations assure reproducibility clinical trials.

Language: Английский

Effects of resistance training on body composition and physical function in elderly patients with osteosarcopenic obesity: a systematic review and meta-analysis DOI Creative Commons
Jia‐ming Yang, Hua Ye, Qiang Zhu

et al.

Archives of Osteoporosis, Journal Year: 2022, Volume and Issue: 17(1)

Published: June 3, 2022

Abstract Summary Osteosarcopenic obesity (OSO) is a complex disease commonly seen in the elderly. We found that resistance training may improve bone mineral density, skeletal muscle mass, and body fat percentage patients with OSO. Therefore, beneficial for elderly OSO worth being promoted. Purpose Investigate effects of on composition physical function osteosarcopenic patients. Methods PubMed, Web Science, Embase, Cochrane Library, Medline, SinoMed, CNKI, Wanfang Database were searched from inception until October 13, 2021.Two independent researchers extracted key information each eligible study. The methodological quality included studies was assessed using Physiotherapy Evidence (PEDro) scale. Risk Bias Tool used to assess risk bias. Grading Recommendations Assessment Development Evaluation (GRADE) evaluate outcomes. Sensitivity analysis indicated stability results. Statistical performed Review Manager 5.3. Results Four randomized controlled meeting inclusion criteria included, 182 participants. Twelve weeks improved density (BMD, mean difference (MD) = 0.01 g/cm 2 , 95% confidence interval (CI): 0.001, 0.02, P 0.03, I 0%), mass (SMM, MD 1.19 kg, CI: 0.50, 1.89, 0.0007, Z score, timed chair rise test (TCR), (BFP, − 1.61%, 2.94, 0.28, 50%) but did not significantly affect index (SMI, 0.20 kg/m 0.25, 0.64, 0.38, 0%) or gait speed (GS). Conclusions Resistance safe effective intervention can many parameters, including BFP, SMM, among good option individuals their fitness.

Language: Английский

Citations

12

Classification, Diagnosis, and Treatment of Obesity-Related Heart Diseases DOI
Dan Chen, Juan Feng,

H. He

et al.

Metabolic Syndrome and Related Disorders, Journal Year: 2024, Volume and Issue: 22(3), P. 161 - 169

Published: Jan. 31, 2024

Evidence-based medicine shows that obesity is associated with a wide range of cardiovascular (CV) diseases. Obesity can lead to changes in cardiac structure and function, which obese cardiomyopathy, subclinical dysfunction, even heart failure. It also increases the risk atrial fibrillation sudden death. Many invasive noninvasive diagnostic methods detect obesity-related disease at an early stage, so appropriate measures be selected prevent adverse CV events. However, studies have shown protective effect on clinical outcomes disease, phenomenon has been termed paradox. The "obesity paradox" essentially refers fact classification defined by body mass index (BMI) does not consider impact heterogeneity prognosis, but simply puts subjects different biochemical characteristics into same category. In any case, indicators such as waist-to-hip ratio, ectopic fat qualitative quantitative, fitness able distinguish risks patients BMI, convenient for intervention way. A multidisciplinary approach, including lifestyle modification, evidence-based generic novel pharmacotherapy, surgical intervention, improve overweight/obese patients.

Language: Английский

Citations

2

Polygonatum kingianum Coll. et Hemsl enzymatic saccharifying extracts alleviate HFD-induced obesity in mice via regulating gut microbiota and AMPK pathways DOI
Yanli Li, Junyuan Huang,

Wenjun Zhao

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 60, P. 104094 - 104094

Published: April 18, 2024

Language: Английский

Citations

2

Increased O-GlcNAcylation induces myocardial hypertrophy DOI
Xiao-Li Chen, Li Zhang,

Hui He

et al.

In Vitro Cellular & Developmental Biology - Animal, Journal Year: 2020, Volume and Issue: 56(9), P. 735 - 743

Published: Sept. 29, 2020

Language: Английский

Citations

18

Western and ketogenic diets in neurological disorders: can you tell the difference? DOI
Karl J. Habashy,

Fatima Ahmad,

Stanley Ibeh

et al.

Nutrition Reviews, Journal Year: 2022, Volume and Issue: 80(8), P. 1927 - 1941

Published: Jan. 14, 2022

The prevalence of obesity tripled worldwide between 1975 and 2016, it is projected that half the US population will be overweight by 2030. pandemic attributed, in part, to increasing consumption high-fat, high-carbohydrate Western diet, which predisposes development metabolic syndrome correlates with decreased cognitive performance. In contrast, low-carbohydrate ketogenic diet has potential therapeutic roles been used manage intractable seizures since early 1920s. brain accounts for 25% total body glucose metabolism and, as a result, especially susceptible changes types nutrients consumed. Here, we discuss principles focus on distinct effects diets progression neurological diseases such epilepsy, Parkinson's disease, Alzheimer's traumatic injury, highlighting need further explore importance standardizing dietary formulations assure reproducibility clinical trials.

Language: Английский

Citations

10