Ecological and public health dimensions of ESBL-producing Escherichia coli in bats: A One Health perspective

Veterinary World, Journal Year: 2025, Volume and Issue: unknown, P. 1199 - 1213

Published: May 1, 2025

Background and Aim: The emergence global dissemination of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli represent a major public health concern. While antibiotic resistance in clinical agricultural settings is well documented, the contribution wildlife, particularly bats, to spread antimicrobial (AMR) remains underexplored. Bats possess unique ecological traits – such as long-distance flight, longevity, adaptability that facilitate their role potential reservoirs vectors antibiotic-resistant bacteria. This review synthesizes findings on occurrence, genetic characteristics, transmission dynamics ESBL-producing E. isolated from bats. Through comprehensive literature studies conducted across five continents, we highlight prevalence multidrug-resistant bat populations, with profiles frequently including β-lactams (bla), aminoglycosides, tetracyclines, fluoroquinolones. Notably, key ESBL genes blaCTX-M, blaTEM, blaSHV, blaOXA have been identified isolates feces (guano), raising significant concern due environmental contamination zoonotic spillover. Risk factors habitat encroachment, anthropogenic waste exposure, use guano further exacerbate risk transmission. Moreover, genomic comparisons suggest phylogenetic overlap between bats those found humans livestock. Given these findings, warrant greater inclusion One Health surveillance frameworks trace AMR gene flow develop targeted interventions. underscores need for integrated monitoring enhanced management policies, stricter biosecurity mitigate risks associated wildlife-origin dissemination. Keywords: resistance, coli, β-lactamase, guano, Health, surveillance, zoonosis.

Language: Английский

How can the microbial community in watershed sediment maintain its resistance in the presence of shifting antibiotic residuals?

Journal of Environmental Management, Journal Year: 2024, Volume and Issue: 368, P. 122242 - 122242

Published: Aug. 19, 2024

Language: Английский

Assessment of health risk of antibiotics resistance genes from human disturbed habitat to wild animals: Metagenomic insights into availability and functional changes of gut microbiome

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 285, P. 117117 - 117117

Published: Sept. 28, 2024

Language: Английский