Asian Journal of Organic Chemistry,
Journal Year:
2020,
Volume and Issue:
9(10), P. 1631 - 1637
Published: July 13, 2020
Abstract
Herein,
we
describe
an
efficient
and
selective
Cu‐catalyzed
C−H
bond
chalcogenation
of
the
indolizine
core,
in
presence
DMSO
applying
ultrasound
irradiation
as
alternative
energy
source.
Under
optimal
conditions,
3‐sulfanylindolizines
(16
examples)
were
prepared
moderate
to
good
yields
starting
from
diorganyl
disulfides
2‐arylindolizines.
When
diphenyl
diselenide
was
used,
1,3‐bis(selanyl)
indolizines
(4
exclusively
obtained
very
yields.
The
use
makes
reaction
faster
more
when
compared
conventional
heating.
Organic Chemistry Frontiers,
Journal Year:
2020,
Volume and Issue:
7(8), P. 1022 - 1060
Published: Jan. 1, 2020
This
review
summarizes
recent
advances
in
C–S
and
C–Se
formationsviatransition
metal-catalyzed
C–H
functionalization
utilizing
directing
groups
to
control
the
site-selectivity.
RSC Advances,
Journal Year:
2019,
Volume and Issue:
9(39), P. 22685 - 22694
Published: Jan. 1, 2019
A
novel
and
sustainable
procedure
was
developed
for
the
synthesis
of
3-selenylindoles
employing
diorganyl
diselenides
indoles
or
electron-rich
arenes
as
starting
materials.
Visible
blue
light
used
to
promote
reaction
without
transition
metal
complexes
organic
photocatalysts
sensitizers.
Additives
such
strong
oxidants
bases
were
not
required.
Moreover,
ethanol
employed
a
benign
solvent
under
mild
conditions.
Through
this
easy
eco-friendly
approach,
several
number
asymmetric
diarylselenides
obtained
in
good
excellent
isolated
yields.
European Journal of Organic Chemistry,
Journal Year:
2020,
Volume and Issue:
2020(14), P. 2110 - 2115
Published: March 17, 2020
A
metal‐free
method
for
the
synthesis
of
3‐sulfanyl
indolizines
from
thiols
and
2‐arylindolizines,
is
reported.
The
reaction
mediated
by
eosin
Y
under
blue
LED
light
irradiation
uses
atmospheric
oxygen
as
oxidant.
By
use
a
catalytic
amount
I
2
,
corresponding
1,3‐bis‐sulfanyl
are
obtained,
in
good
yields.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(36), P. 5415 - 5418
Published: Jan. 1, 2023
For
the
first
time,
we
report
transition
metal-free
electrochemical
site-selective
direct
C–H
sulfenylation/selenylation
of
chromone-fused
indolizine
compounds
(CFIs)
to
afford
corresponding
CFIs
thioethers
and
selenoethers
in
58–96%
yields.
ChemistrySelect,
Journal Year:
2024,
Volume and Issue:
9(3)
Published: Jan. 17, 2024
Abstract
Organic
synthesis
involves
the
production
of
important
chemical
structures
using
scalable
and
cost‐effective
methods
that
are
also
environmentally
friendly.
In
this
review,
a
detailed
analysis
use
iodine
DMSO
in
various
synthetic
routes
for
preparation
valuable
targets
presented.
These
reduce
acceptance
on
expensive
additives
reagents,
offer
more
sustainable
solution
these
scaffolds.
The Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 16, 2025
Biaryl
sulfides
are
important
scaffolds
found
in
various
natural
products
and
pharmaceutically
active
compounds.
One
of
the
main
approaches
for
synthesis
this
compound
class
involves
substitution
arenes
using
electrophilic
thioaryl
species.
However,
these
methods
generally
require
acidic
activation
electrophile,
more
forcing
conditions,
long
reaction
times.
Here,
we
describe
combination
super
Lewis
acid
iron(III)
triflimide
with
saccharin-based
thioarylation
reagents
rapid
unsymmetrical
biaryl
under
mild
conditions.
This
approach
was
effective
electron-deficient
species
that
performed
poorly
previous
methods,
allowing
efficient
functionalization
bioactive
Applied Organometallic Chemistry,
Journal Year:
2021,
Volume and Issue:
36(1)
Published: Oct. 14, 2021
Diaryl
sulfides
are
a
highly
valuable
class
of
sulfur‐containing
compounds
presented
in
numerous
drugs
with
broad
range
therapeutic
activities
and
also
employed
as
precursors
to
other
higher
oxidation
state
important
bioactivities.
Thus,
the
development
efficient
approaches
for
C−S
bond
formation
is
essential
synthetic
medicinal
chemistry.
Many
efforts
have
been
made
constructing
bonds
via
various
protocols.
This
review
highlights
current
strategies
emphasizing
metal‐catalyzed
reactions
(MRC),
metal‐free
approaches,
photocatalysis
reaction
s
,
MCR's
from
2012
onwards.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
22(4), P. 645 - 681
Published: Dec. 23, 2023
Organochalcogen
compounds
are
prevalent
in
numerous
natural
products,
pharmaceuticals,
agrochemicals,
polymers,
biological
molecules
and
synthetic
intermediates.
Direct
chalcogenation
of
C-H
bonds
has
evolved
as
a
step-
atom-economical
method
for
the
synthesis
chalcogen-bearing
compounds.
Nevertheless,
direct
severely
lags
behind
C-C,
C-N
C-O
bond
formations.
Moreover,
compared
with
monochalcogenation,
reports
selective
mono-/dichalcogenation
exclusive
dichalcogenation
relatively
scarce.
The
past
decade
witnessed
significant
advancements
various
C(sp
Organic & Biomolecular Chemistry,
Journal Year:
2021,
Volume and Issue:
19(24), P. 5284 - 5288
Published: Jan. 1, 2021
An
efficient
and
straightforward
metal-free
regioselective
C–H
dithiocarbamation
of
indolizines
with
tetraalkylthiuram
disulfide
has
been
described.
A
series
indolizines-dithiocarbamates
derivatives
were
easily
accessed
in
good
yields.
