Miniaturized and portable device for Noninvasive, ultrasensitive and point-of-care diagnosis by engineered Metal-Carbide-based field effect transistor

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160264 - 160264

Published: Feb. 1, 2025

Language: Английский

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Advances in Photonic Crystal Research for Structural Color

Advanced Materials Technologies, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 3, 2024

Abstract Structural color is a remarkable physical phenomenon that exists widely in nature. Unlike traditional rendering methods, they are realized mainly through micro/nanostructures interfere, diffract, scatter light, and exhibit long‐life environmental‐friendly effects. In nature, few organisms use their color‐changing system to transmit information, such as courtship, warning, or disguise. Meanwhile, some natural inorganic minerals can also structural colors. Learning from scientists have achieved large‐scale design manufacturing technology for artificial photonic crystals. Photonic crystals unique microstructure forms band gap under the action of periodic potential field, consequently causing Bragg scattering due arrangement different refractive index media within them. Because apparent ability form local photons at crystal defects, been extensively studied recent years broad application prospects fibers, optical computers, chips, other fields. this review, research, properties, applications presented, well insight into future developments

Language: Английский

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Ag@Au core–shell nanoparticle-based surface-enhanced Raman scattering coupled with chemometrics for rapid determination of chloramphenicol residue in fish

Food Chemistry, Journal Year: 2023, Volume and Issue: 438, P. 138026 - 138026

Published: Nov. 16, 2023

Language: Английский

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Carbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: May 9, 2023

Photothermal therapy (PTT) in the second near-infrared (NIR-II) window has attracted extensive attention due to benefits high maximum permissible exposure and penetration depth. Current photothermal agents generally show a broadband absorption accompanied by gradual attenuation of NIR-II window, leading poor effect PTT. It remains great challenge gain with strong characteristic regions. To overcome this problem, based on carbon dots (CDs)-mediated growth strategy, we proposed simple feasible approach prepare plasmonic gold nanodendrites (AuNDs) enhance therapeutic

Language: Английский

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Advanced nano engineering of surface-enhanced Raman scattering technologies for sensing applications

Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102217 - 102217

Published: May 6, 2024

Language: Английский

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NIR‐II Surface‐Enhanced Raman Scattering Nanoprobes in Biomedicine: Current Impact and Future Directions

Small, Journal Year: 2024, Volume and Issue: unknown

Published: June 7, 2024

Abstract The field of second near‐infrared (NIR‐II) surface‐enhanced Raman scattering (SERS) nanoprobes has made commendable progress in biomedicine. This article reviews recent advances and future development NIR‐II SERS nanoprobes. It introduces the fundamental principles highlights key window, including reduced tissue attenuation, deep penetration, maximized allowable exposure, improved photostability. discussion directions includes refinement nanoprobe substrates, emphasizing tailoring optical properties metallic SERS‐active nanoprobes, exploring non‐metallic alternatives. intricacies designing reporters for resonance potential these to advance are also discussed. integration artificial intelligence (AI) into design represents a cutting‐edge approach overcome current challenges. examines emergence techniques through‐tissue detection, toward tomography. acknowledges instrumental advancements like charge‐coupled device sensitivity accelerated imaging speeds. concludes by addressing critical aspects biosafety, ease functionalization, compatibility, path clinical translation. With comprehensive overview achievements prospects, this review aims illuminate innovate diagnostic therapeutic approaches

Language: Английский

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Label-Free Surface-Enhanced Raman Spectroscopy with Machine Learning for the Diagnosis of Thyroid Cancer by Using Fine-Needle Aspiration Liquid Samples

Biosensors, Journal Year: 2024, Volume and Issue: 14(8), P. 372 - 372

Published: July 31, 2024

The incidence of thyroid cancer is increasing worldwide. Fine-needle aspiration (FNA) cytology widely applied with the use extracted biological cell samples, but current FNA labor-intensive, time-consuming, and can lead to risk false-negative results. Surface-enhanced Raman spectroscopy (SERS) combined machine learning algorithms holds promise for diagnosis. In this study, we develop a label-free SERS liquid biopsy method rapid accurate diagnosis by using washout fluids. These supernatants are mixed silver nanoparticle colloids, dispersed in quartz capillary measurements discriminate between healthy malignant samples. We collect spectra 36 samples (18 18 benign) compare four classification models: Principal Component Analysis-Linear Discriminant Analysis (PCA-LDA), Random Forest (RF), Support Vector Machine (SVM), Convolutional Neural Network (CNN). results show that CNN algorithm most precise, high accuracy 88.1%, sensitivity 87.8%, area under receiver operating characteristic curve 0.953. Our approach simple, convenient, cost-effective. This study indicates assisted deep models great early detection screening cancer.

Language: Английский

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Unlocking the Potential of RGD-Conjugated Gold Nanoparticles: A New Frontier in Targeted Cancer Therapy, Imaging, and Metastasis Inhibition

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(42), P. 10786 - 10817

Published: Jan. 1, 2024

The review highlights the potential of RGD-conjugated AuNPs in cancer diagnosis and treatment, including breast cancer. It emphasizes need for further research to fully realize this technology’s inspire future investigations.

Language: Английский

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Tumor microenvironment-responsive gold nanodendrites for nanoprobe-based single-cell Raman imaging and tumor-targeted chemo-photothermal therapy

Smart Materials in Medicine, Journal Year: 2023, Volume and Issue: 4, P. 680 - 689

Published: Jan. 1, 2023

Nanodendrite particles (NDs) with densely branched structures and biomimetic architectures have exhibited great promise in tumor therapy owing to their prolonged vivo circulation time exceptional photothermal efficiency. Nevertheless, traditional NDs are deficient terms of specific surface modification targeting tumors, which restrict potential for broader clinical applications. Here, we developed coronavirus-like gold through a seed-mediated approach using silk fibroin (SF) as capping agent. Our results demonstrate that these favorable drug-loading capacity (∼65.25%) light-triggered release characteristics doxorubicin hydrochloride (DOX). Additionally, functionalized probes surface-enhanced Raman scattering (SERS) characteristics, enabling high-sensitivity imaging unstained single cells. Moreover, allowed real-time monitoring endocytic over 24 ​h. Furthermore, [email protected] conjugated tumor-targeting peptides mild hyperthermia, minimal cytotoxicity, effective towards cancer cells vitro, well responsiveness the microenvironment (TME) vivo. These unique properties led highest level synergistic tumor-killing efficiency when stimulated by near-infrared (NIR) laser at 808 ​nm. Therefore, our virus-like ND SF presents novel type nanocarrier exhibits significant applications precision medicine.

Language: Английский

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Single-atom catalysts for biosensing: Progress in theoretical and mechanistic understanding

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 502, P. 215606 - 215606

Published: Dec. 26, 2023

Language: Английский

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