Food Frontiers,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 22, 2024
Abstract
Chemoresistance
is
a
major
cause
of
breast
cancer
(BC)
recurrence
and
metastasis,
chemotherapy
resistance
comes
from
tumor
stemness.
Our
previous
study
showed
that
quinoa
bran
terpenoids
(QBT)
exhibited
significant
antitumor
activity.
In
this
study,
we
found
QBT
increased
the
sensitivity
drug‐resistant
BC
cells
to
chemotherapeutic
drugs
adriamycin
(ADR)
taxol
(TAX).
A
novel
lncRNA
667012
was
identified
along
with
treatment.
Moreover,
overexpression
promoted
drug
resistance,
reduction
restored
resistant
cells.
More
importantly,
findings
revealed
stemness
maintenance
via
stemness‐related
Wnt
pathway.
Furthermore,
result
reduced
expression
inhibited
activation
β‐catenin,
thereby
attenuating
characteristics
enhancing
chemosensitivity.
Consistently,
data
were
confirmed
in
xenograft
mice
model.
These
results
suggest
could
reverse
chemoresistance
by
inhibiting
It
has
potential
be
developed
as
agent
or
chemosensitizer
for
Food Physics,
Journal Year:
2023,
Volume and Issue:
1, P. 100003 - 100003
Published: Aug. 17, 2023
The
field
of
3D
food
printing
is
poised
to
revolutionize
the
gastronomic
landscape
by
offering
precise
and
customized
creations.
This
short
review
explores
fundamental
concepts
physical
qualities
that
influence
design,
structure,
taste
3D-printed
food,
examining
interplay
between
physics
including
viscosity,
rheology,
surface
tension,
heat
transfer,
contributing
understanding
advancing
technology.
basics
printing,
physics-driven
design
structure
printed
role
transfer
thermal
effects,
sensory
aspects
flavor
perception
in
are
discussed.
Furthermore,
it
highlights
recent
advances
innovations
along
with
challenges
lie
ahead
future
directions
for
research.
perspective
underscores
importance
shaping
potential
applications
ranging
from
personalized
nutrition
sustainable
production.
By
embracing
a
approach,
we
can
unlock
this
disruptive
technology's
full
transform
how
produce
experience
food.
Processes,
Journal Year:
2025,
Volume and Issue:
13(1), P. 120 - 120
Published: Jan. 5, 2025
This
review
provides
an
overview
of
recent
developments
in
Citrus
aurantium
L.
(sour
or
bitter
orange),
focusing
on
its
bioactive
compounds,
innovative
extraction
techniques,
and
technological
applications.
C.
is
rich
compounds
such
as
flavonoids
(naringin,
hesperidin,
kaempferol,
quercetin),
essential
oils
(β-pinene,
limonene),
vitamin
C,
which
represents
significant
biological
activities
including
antioxidant,
antimicrobial,
anti-inflammatory,
anticancer
effects.
The
discusses
traditional
methods,
solvent
hydrodistillation,
alongside
newer,
eco-friendly
approaches
like
ultrasound-assisted
extraction,
microwave-assisted
supercritical
fluid
natural
deep
eutectic
solvents.
It
also
highlights
cutting-edge
molecular
imprinting
polymer-based
enable
the
more
efficient
enrichment
purification
specific
synephrine.
Finally,
examines
diverse
industrial
applications
these
sectors
foods,
pharmaceuticals,
cosmetics,
while
emphasizing
growing
need
for
sustainable
technologies.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(21), P. 15914 - 15914
Published: Nov. 2, 2023
Nowadays,
more
and
researchers
engage
in
studies
regarding
the
extraction
of
bioactive
compounds
from
natural
sources.
To
this
end,
plenty
have
been
published
on
topic,
with
interest
field
growing
exponentially.
One
major
aim
such
is
to
maximize
yield
and,
simultaneously,
use
procedures
that
adhere
principles
green
chemistry,
as
much
possible.
It
was
not
until
recently
pulsed
electric
(PEF)
technology
has
put
good
achieve
goal.
This
new
technique
exhibits
many
advantages,
compared
other
techniques,
they
successfully
reaped
for
production
extracts
enhanced
concentrations
compounds.
In
advancing
research,
a
understanding
existing
literature
mandatory
develop
advanced
concepts
future.
The
review
provide
thorough
discussion
most
important
applications
PEF
enhancement
polyphenols
fresh
food
products
by-products,
well
discuss
current
limitations
prospects
field.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 18
Published: June 27, 2024
Anthocyanins
(ACNs)
are
secondary
metabolites
found
in
plants.
Due
to
their
impressive
biological
activities,
ACNs
have
gained
significant
popularity
and
extensive
application
within
the
food,
pharmaceutical,
nutraceutical
industries.
A
derivative
of
ACNs:
pyranoanthocyanins
(PACNs)
possesses
more
stable
properties
interesting
activities.
However,
conventional
methods
for
production
ACNs,
including
chemical
synthesis
plant
extraction,
involve
organic
solvents.
Microbial
from
renewable
biomass,
such
as
amino
acids
or
flavonoids,
is
considered
a
sustainable
environmentally
friendly
method
large-scale
ACNs.
Recently,
construction
microbial
cell
factories
(MCFs)
efficient
biosynthesis
PACNs
has
attracted
much
attention.
In
this
review,
we
summarize
cases
analyze
bottlenecks
reconstructing
metabolic
pathways
synthesizing
microorganisms.
Consequently,
there
an
urgent
need
investigate
mechanisms
behind
development
MCFs
synthesis.
Such
research
also
holds
promise
advancing
food
pigments.
Meanwhile,
propose
potential
solutions
bottleneck
problem
based
on
engineering
enzyme
engineering.
Finally,
prospects
natural
biotechnology
discussed.
MEDICINUS,
Journal Year:
2025,
Volume and Issue:
38(3), P. 32 - 42
Published: March 1, 2025
Studi
fraksi
bioaktif
telah
muncul
sebagai
bidang
transformatif
dalam
farmakologi
modern,
menekankan
pemurnian
dan
isolasi
senyawa
yang
dipandu
bioassay
dengan
potensi
terapeutik.
Makalah
ini
mengeksplorasi
mekanisme,
metodologi,
implikasi
memajukan
penemuan
obat.
Mengambil
pengetahuan
etnofarmakologi,
makalah
menyoroti
integrasi
kearifan
tradisional
teknologi
modern.
Meskipun
ada
tantangan
standardisasi
skalabilitas,
sifat
interdisipliner
menggarisbawahi
potensinya
untuk
mengatasi
kesehatan
global.
Arah
masa
depan
meliputi
pengoptimalan
teknik
ekstraksi,
peningkatan
bioavailabilitas,
praktik
berkelanjutan.
