Wound dressings using electrospun nanofibers: mechanisms, applications, and future directions DOI
Ruiyu Zhou, Yunqi Ma, Min Yang

et al.

European Polymer Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113900 - 113900

Published: March 1, 2025

Language: Английский

Polyurethane-based nanofibrous mat containing porphyrin with photosensitivity and bactericidal properties can promote cutaneous tissue healing in rats DOI Creative Commons

Solmaz Saghebasl,

Hassan Amini, Abbas Nobakht

et al.

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: Sept. 4, 2023

The regeneration of cutaneous tissue is one the most challenging issues in human regenerative medicine. To date, several studies have been done to promote healing with minimum side effects. potential polyurethane (PU)/Poly (caprolactone)-poly (ethylene glycol)-poly (caprolactone) (PCEC)/chitosan (CS) (PCS) nanofibrous mat cationic photosensitizer meso tetrakis (N-methyl pyridinium-4-yl) porphyrin tetratosylate salt (TMP) was examined. CS tripolyphosphate nanoparticles (CSNPs) were prepared and loaded by TMP provide an efficient drug release system (TMPNPs) for delivery wound healing. In vitro setting, parameters such as bactericidal effects, cytocompatibility, hemolytic effects mats investigated a rat model full-thickness injury. PCS/TMP/TMPNPs nanofibers can efficiently aqueous phase. addition TMPNPs PU backbone increased hydrophilicity, degradation, reduced mechanical properties. culture fetal foreskin fibroblasts (HFFF2) on scaffold led survival rate morphological adaptation analyzed MTT SEM images. Irradiation red laser (635 nm, 3 J/cm2) 30 s viability S. aureus E. Coli bacteria plated PCS/TMP compared PU/PCEC (PC) PU/PCEC/CS groups, indicating prominent antibacterial (p < 0.05). Data indicated that enhanced excisional reduction inflammatory response fibrotic changes PC, PCS groups Immunofluorescence imaging levels Desmoglein rats received other groups. It found PU-based appropriate accelerate injured skin.

Language: Английский

Citations

13
Valorised Calcium-Rich Biomass from Fish Waste and Eggshells in the Fabrication of Antibacterial Scaffold for Wound Healing Applications: A Review DOI

S. Ankul Singh,

Chitra Vellapandian, Disha D. Shah

et al.

Waste and Biomass Valorization, Journal Year: 2023, Volume and Issue: 15(4), P. 1917 - 1941

Published: Nov. 15, 2023

Language: Английский

Citations

13
Piperine-loaded electrospun nanofibers, an implantable anticancer controlled delivery system for postsurgical breast cancer treatment DOI
Delaram Babadi, Simin Dadashzadeh, Zahra Shahsavari

et al.

International Journal of Pharmaceutics, Journal Year: 2022, Volume and Issue: 624, P. 121990 - 121990

Published: July 6, 2022

Language: Английский

Citations

22
Recent trends in diabetic wound healing with nanofibrous scaffolds DOI
Sindhuspoorthy Chappidi, Buddolla Viswanath, Seshadri Reddy Ankireddy

et al.

European Journal of Pharmacology, Journal Year: 2023, Volume and Issue: 945, P. 175617 - 175617

Published: Feb. 24, 2023

Language: Английский

Citations

11
Wound dressings using electrospun nanofibers: mechanisms, applications, and future directions DOI
Ruiyu Zhou, Yunqi Ma, Min Yang

et al.

European Polymer Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113900 - 113900

Published: March 1, 2025

Language: Английский

Citations

0