Investigation of cell damage of periodontopathic bacteria exposed to silver, zirconium oxide, and silicon oxide nanoparticles as antibacterial agents DOI Creative Commons
Yeşim Dağlıoğlu, Mustafa Cihan Yavuz, Ömer Ertürk

et al.

Micro & Nano Letters, Journal Year: 2023, Volume and Issue: 18(9-12)

Published: Sept. 1, 2023

Abstract Antibiotic resistance is one of the biggest public health problems our time. The nanoparticles are a powerful alternative to these antibiotics. Engineered show toxic effects on bacteria by different mechanisms. bacteria–cell interaction engineered exerts their through changes in cell wall, membrane, and cytoplasm content/density. Thus, death occurs as result deformation. In this study, cellular damage silver nanoparticles, which known have strong antibacterial properties, zirconium oxide silicon engineering less known, periodontopathic ( Prevotella intermedia Aggregatibacter actinomycetemcomitans ) bacteria, were investigated ultrastructural changes. lysis separation membrane observed. Both types treated with Ag ENP more hollow than other two nanoparticles.

Language: Английский

Process optimization for green synthesis of silver nanoparticles using Rubus discolor leaves extract and its biological activities against multi-drug resistant bacteria and cancer cells DOI Creative Commons
Saeed Ghasemi, Sara Dabirian,

Faezeh Kariminejad

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 19, 2024

Abstract Multi-drug resistant (MDR) bacteria are considered a serious public health threat. Also, increasing rate of resistance to anticancer drugs, as well their toxicity, is another point concern. Therefore, the new antibacterial and agents always needed. The synthesizing silver nanoparticles (AgNPs) using medicinal plants, an effective approach for developing novel agents. Rubus discolor , native species Caucasus region, produces leaves that typically discarded by-product raspberry production. present study has focused on optimizing green synthesis AgNPs R. extract through response surface methodology. optimal values were AgNO 3 concentration 7.11 mM, time 17.83 h, temperature 56.51 °C, percentage 29.22. production was confirmed UV–visible spectroscopy (λ max at 456.01 nm). TEM analysis revealed well-dispersed (an average size 37 XRD crystalline structure. EDX detected strong peak keV corresponded Ag. zeta potential value (− 44.2 mV) indicated stability nanoparticles. FT-IR spectra showed presence various functional groups from plant compounds, which play important role in capping bio-reduction processes. impressive activities against MDR Escherichia coli Pseudomonas aeruginosa (MIC ranging 0.93 3.75 mg ml −1 ). phytochemical phenolics, tannins, flavonoids AgNPs. They also significant cytotoxic effects A431, MCF-7, HepG2 cells (IC 50 11 49.1 µg −l

Language: Английский

Citations

48
Green synthesis and characterizations of bi-functional Mo-doped ZnO nanostructures for antimicrobial and photocatalytic applications DOI
N.R. Khalid,

Muntaha Sabir,

Faisal Ali

et al.

Materials Chemistry and Physics, Journal Year: 2023, Volume and Issue: 296, P. 127306 - 127306

Published: Jan. 5, 2023

Language: Английский

Citations

27
Biogenic Synthesis of Multifunctional Silver Oxide Nanoparticles (Ag2ONPs) Using Parieteria alsinaefolia Delile Aqueous Extract and Assessment of Their Diverse Biological Applications DOI Creative Commons

Zakir Ullah,

Farhat Gul,

Javed Iqbal

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(4), P. 1069 - 1069

Published: April 20, 2023

Green nanotechnology has made the synthesis of nanoparticles a possible approach. Nanotechnology significant impact on several scientific domains and diverse applications in different commercial areas. The current study aimed to develop novel green approach for biosynthesis silver oxide (Ag2ONPs) utilizing Parieteria alsinaefolia leaves extract as reducing, stabilizing capping agent. change color reaction mixture from light brown reddish black determines Ag2ONPs. Further, techniques were used confirm Ag2ONPs, including UV-Visible spectroscopy, Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM), Energy-dispersive (EDX), zeta potential dynamic scattering (DLS) analyses. Scherrer equation determined mean crystallite size ~22.23 nm Additionally, vitro biological activities have been investigated therapeutic potentials. Radical scavenging DPPH assay (79.4%), reducing power (62.68 ± 1.77%) total antioxidant capacity (87.5 4.8%) evaluated assess antioxidative disc diffusion method was adopted evaluate antibacterial antifungal potentials Ag2ONPs using concentrations (125-1000 μg/mL). Moreover, brine shrimp cytotoxicity LC50 value calculated 2.21 μg/mL. biocompatibility red blood cells (<200 μg/mL) confirmed biosafe biocompatible nature Alpha-amylase inhibition performed reported 66% inhibition. In conclusion, currently synthesized exhibited strong proved an attractive eco-friendly candidate. future, this preliminary research work will be helpful source open new avenues fields, pharmaceutical, biomedical pharmacological sectors.

Language: Английский

Citations

26
Aspartic Acid-Based Nano-Copper Induces Resilience in Zea mays to Applied Lead Stress Via Conserving Photosynthetic Pigments and Triggering the Antioxidant Biosystem DOI Open Access
Rehman Ullah,

Zakir Ullah,

Javed Iqbal

et al.

Sustainability, Journal Year: 2023, Volume and Issue: 15(16), P. 12186 - 12186

Published: Aug. 9, 2023

Heavy metal stress, including lead, adversely affects the growth and yield of several economically important crops, leading to food challenges significant economic losses. Ameliorating plant responses various environmental stresses is one promising areas research for sustainable agriculture. In this study, we evaluated effect aspartic acid-functionalized copper nanoparticles on photosynthetic efficiency antioxidation system maize plants under Pb toxicity. The ion reduction method was employed synthesis CuNPs, using ascorbic acid as reducing agent surface functionalizing agent. Isolated experiments laboratory field conditions were performed a randomized complete block design (RCBD). Seeds primed in water, 1.0, 5.0, 10 µg/mL Asp-CuNPs sown 0, 500, 1000 mg/L stress conditions, while seeds along with foliar-applied Asp-CuNP grown applied obtained data statistically analyzed TWANOVA. experiment shows that act both regulator (PGR) inhibitor (PGI), depending upon their concentration, whereby PGR at concentration 1 ≤ X ≤10 µg/mL. confirms seed priming foliar spraying activate embryos enhance dose-dependent manner. addition, (10 µg/mL) significantly increase chlorophyll content 0.87 mg/g from 0.53 (untreated) when exposed toxicity mg/kg soil. It noteworthy induce resilience (1000 soil) by its root absorption 3.68 (0 Asp-CuNPs) 1.72 application Asp-CuNPs. Additionally, histochemical analyses NBT hydrogen peroxide revealed ROS accretion treated declined because augmentation antioxidant enzyme (POD, SOD, APOX, etc.) activities Our findings suggest amino regulate defensive mechanisms related lead tolerance, which approach induction resistivity heavy stress.

Language: Английский

Citations

23
Physical properties of multifunctional TM-doped ZnO nanorods and their photocatalytic and anti-bacterial activities DOI
Yasir Zaman, Muhammad Zahid Ishaque,

Yasir Yousaf

et al.

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 30(42), P. 95860 - 95874

Published: Aug. 10, 2023

Citations

23
Green-route synthesis of ZnO nanoparticles via Solanum surattense leaf extract: Characterization, biomedical applications and their ecotoxicity assessment of zebrafish embryo model DOI
Chinnasamy Ragavendran, Chinnaperumal Kamaraj, Abdulwahed Fahad Alrefaei

et al.

South African Journal of Botany, Journal Year: 2024, Volume and Issue: 167, P. 643 - 662

Published: March 11, 2024

Language: Английский

Citations

11
Biosynthesis of ZnO.Ag2O3 using aqueous extract of Haplophyllum obtusifolium: Characterization and cell toxicity activity against liver carcinoma cells DOI Creative Commons
M. Halimi, Mohabat Nadaf, Mohammad Ehsan Taghavizadeh Yazdi

et al.

Micro & Nano Letters, Journal Year: 2023, Volume and Issue: 18(6)

Published: June 1, 2023

Abstract The zinc oxide‐silver oxide nanocomposite (ZnO.Ag 2 O 3 particles) was prepared by using an aqueous plant extract of Haplophyllum obtusifolium for the first time. Powder X‐ray diffraction (PXRD), Fourier transforms spectroscopy (FTIR), field emission microscopy (FESEM), energy dispersive analysis (EDX), and transmission electron (TEM) were applied to analyze structure, functional groups, morphology, purity nanocomposite. PXRD revealed formulation ZnO.Ag particles. investigation groups has demonstrated presence some carbonated impurities along with absorbed water in composition Morphologically, particles have formed a petal‐like shape different sizes. EDX also confirmed sample 4.78% silver formula. Additionally, TEM spherical rectangular shapes particle size 80.43 ± 46.73 nm. Moreover, used against cancer cells, which shown synthesized NCs toxic effect liver cells concentration time‐dependent manner.

Language: Английский

Citations

20
In vitro anticancer and antibacterial performance of biosynthesized Ag and Ce co-doped ZnO NPs DOI Open Access
Nouf M. Al-Enazi, Khawla Alsamhary, Mansour Kha

et al.

Bioprocess and Biosystems Engineering, Journal Year: 2022, Volume and Issue: 46(1), P. 89 - 103

Published: Dec. 20, 2022

Language: Английский

Citations

28
Management of Brain Cancer and Neurodegenerative Disorders with Polymer-Based Nanoparticles as a Biocompatible Platform DOI Creative Commons
Mehdi Bazi Alahri, Alhawarin Jibril Ibrahim, Mahmood Barani

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(2), P. 841 - 841

Published: Jan. 14, 2023

The blood–brain barrier (BBB) serves as a protective for the central nervous system (CNS) against drugs that enter bloodstream. BBB is key clinical in treatment of CNS illnesses because it restricts drug entry into brain. To bypass this and release relevant brain matrix, nanotechnology-based delivery systems have been developed. Given unstable nature NPs, an appropriate amount biocompatible polymer coating on NPs thought to role reducing cellular cytotoxicity while also boosting stability. Human serum albumin (HSA), poly (lactic-co-glycolic acid) (PLGA), Polylactide (PLA), (alkyl cyanoacrylate) (PACA), gelatin, chitosan are only few significant polymers mentioned. In review article, we categorized polymer-coated nanoparticles from basic complex discussed their application novel carriers

Language: Английский

Citations

16
Facile green synthesis inorganic cuprous oxide nanoparticles and their antibacterial properties DOI Creative Commons
Dalal Nasser Binjawhar, Salam S. Alsharari, Aisha Nawaf AlBalawi

et al.

Micro & Nano Letters, Journal Year: 2023, Volume and Issue: 18(1)

Published: Jan. 1, 2023

Abstract Here, the authors described a sustainable green synthesis approach to synthesize cuprous oxide nanoparticles (NPs) using Olea europaea extract. The resulting synthesized NPs were characterized by UV–Visible spectra, scanning electron microscopy (SEM)/energy‐dispersive X‐ray spectroscopy (EDS), transmission (TEM), and diffraction (XRD). average crystallite size of about 30 nm was calculated Scherrer formula. According TEM, are spherical shaped. NP provides good antibacterial activity versus two strains compared aqueous extract; has higher MIC against Staphylococcus aureus Klebsiella pneumoniae .

Language: Английский

Citations

14