Nanobiotechnology Reports, Journal Year: 2024, Volume and Issue: 19(S1), P. S195 - S201
Published: Dec. 1, 2024
Language: Английский
Nanobiotechnology Reports, Journal Year: 2024, Volume and Issue: 19(S1), P. S195 - S201
Published: Dec. 1, 2024
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135656 - 135656
Published: Sept. 1, 2024
Language: Английский
Citations
4Journal of Pharmaceutical Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 103802 - 103802
Published: April 1, 2025
Language: Английский
Citations
0Bioinorganic Chemistry and Applications, Journal Year: 2025, Volume and Issue: 2025(1)
Published: Jan. 1, 2025
Bioactive molecule‐based synthesis of silver nanoparticles (AgNPs) offers an eco‐friendly approach with high therapeutic potential; however, research in this area remains limited. This study introduces hot melt extrusion (HME) technology to enhance the extraction efficiency bioactive compounds, including astaxanthin, from microalgae Haematococcus pluvialis (Hp). AgNPs were synthesized using HME‐processed Hp (H‐Hp/AgNPs), confirmed by a color change and UV–vis absorption spectrum. The resulting H‐Hp/AgNPs exhibited average size 129.7 ± 10.4 nm, polydispersity index 0.2 0.3, zeta potential −31.54 mV, indicating stability. demonstrated antibacterial activity inhibiting growth biofilm formation antibiotic‐resistant bacteria. Cell viability assays revealed that normal cells maintained over 100% at most concentrations H‐Hp/AgNPs, while cancer significant cytotoxicity (34.1 3.1%) 250 μg/mL. Furthermore, induced apoptosis MDA‐MB 231 cells, as evidenced mitochondrial membrane loss, nuclear condensation, apoptosis, through AO/EB, Rh123, PI staining. Additionally, showed no hemolytic below μg/mL, ensuring safety. In conclusion, highlights biosynthesized promising candidates antioxidant, antibacterial, biocompatibility, anticancer properties.
Language: Английский
Citations
0Nanobiotechnology Reports, Journal Year: 2024, Volume and Issue: 19(S1), P. S195 - S201
Published: Dec. 1, 2024
Language: Английский
Citations
0