Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2665 - 2665

Published: Nov. 22, 2024

Liver fibrosis represents a common pathway in the progression of various chronic liver diseases towards cirrhosis and failure. Extracellular vesicles (EVs) are membrane-enclosed particles secreted by diverse cell types, including exosomes, microvesicles, apoptotic vesicles, recently identified migrasomes. These can be taken up recipient cells, thereby modulating their function through transport cargo molecules. EVs facilitate intercellular communication play significant role development fibrosis. Moreover, detection body fluids offers sensitive diagnostic tools for assessing Additionally, may serve as therapeutic targets, potential agents, drug delivery vehicles. This article reviews recent advances field concerning related diseases, with particular focus on newly discovered migrasomes intracellular crosstalk within liver.

Language: Английский