Influenza Viruses Detected in Lethal Cases in the Russian Federation in the 2023–2024 Respiratory Virus Season DOI
N. D. Boldyrev, А. С. Панова, Natalia Kolosova

et al.

ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, Journal Year: 2024, Volume and Issue: unknown, P. 68 - 74

Published: Nov. 1, 2024

Introduction: Influenza is a highly contagious disease which can cause severe complications and even death, particularly in high-risk populations. Continuous monitoring careful testing of seasonal influenza viruses, especially for cases, necessary to develop optimize prevention treatment. Objective: To establish genetic antigenic characteristics viruses detected lethal cases the Russian Federation 2023–2024 respiratory virus season. Materials methods: From September 29, 2023 June 1, 2024, 859 specimens from (nasopharyngeal swabs) 101 autopsy trachea, bronchi, lungs 57 regions were analyzed by PCR. For those with sufficient amount material, whole-genome sequencing was performed using Illumina MiSeq platform. Results: The season characterized dominance A/H3N2 subclade 2a.3a.1. A/H1N1pdm09 type B lesser extent that period. Additional diversification observed during accumulation amino acid substitutions hemagglutinin sites. Most among at high risk unvaccinated. No mutations associated increased pathogenicity virulence identified cases. molecular markers drug resistance neuraminidase inhibitors baloxavir marboxil all tested Conclusion: diseases State Research Center Virology Biotechnology “Vector” similar recovered patients. isolated genetically antigenically vaccine strain had no or resistance.

Language: Английский

Chikungunya virus in Europe: A retrospective epidemiology study from 2007 to 2023 DOI Creative Commons
Qian Liu, Hong Shen, Li Gu

et al.

PLoS neglected tropical diseases, Journal Year: 2025, Volume and Issue: 19(3), P. e0012904 - e0012904

Published: March 7, 2025

Background Chikungunya virus (CHIKV), a mosquito-borne alphavirus, is responsible for disease outbreaks worldwide. However, systematic knowledge of spatiotemporal distribution and risk patterns CHIKV in mainland Europe remains unclear. Our aim was to decipher the epidemiological characteristics, diversity, clinical manifestations CHIKV. Methods In this retrospective study, we retrieved surveillance bulletins chikungunya infections reported during 2007–2023 depict characteristics. We performed genotyping phylogenetic analyses examine evolution mutation. also searched PubMed, Web Science, Google Scholar conduct meta-analyses manifestations. Results 4730 cases across twenty-two countries were documented from 2007–2022, with no 2023. The age-standardized incidence rate highest 2014 (0.31), significant variations observed each country per year. Although autochthonous occurred several countries, majority travel-related, individuals mainly getting infected summer vacation. Most travel-related as being acquired India (11.7%), followed by Dominican Republic (9.0%), Guadeloupe (8.7%), Thailand (7.8%). Genotyping genome sequences identified two genotypes, belonging II-ECSA. E1 A226V mutation detected outbreaks, including Italy 2007 France 2017. most common symptoms fever (97.6%), joint pain (94.3%), fatigue (63.5%), skin rash (52.3%). Conclusion suitable niches are expanding due climate change global travel. With absence specific antiviral treatments vaccines still development, vector control essential suppressing re-emergence epidemics

Language: Английский

Citations

0
Insights into Genetic and Antigenic Characteristics of Influenza A(H1N1)pdm09 Viruses Circulating in Sicily During the Surveillance Season 2023–2024: The Potential Effect on the Seasonal Vaccine Effectiveness DOI Creative Commons
Fabio Tramuto, Carmelo Massimo Maida,

Giulia Randazzo

et al.

Viruses, Journal Year: 2024, Volume and Issue: 16(10), P. 1644 - 1644

Published: Oct. 21, 2024

After disruption in the influenza circulation due to emergence of SARS-CoV-2, intensity seasonal outbreaks has returned pre-pandemic levels. This study aimed evaluate evolution and variability whole-genome sequences A(H1N1)pdm09, predominant virus Sicily (Italy) during season 2023-2024. The potential vaccine efficacy was calculated using

Language: Английский

Citations

2
The circulating characteristics of common respiratory pathogens in Ningbo, China, both before and following the cessation of COVID-19 containment measures DOI Creative Commons
Qian Sun, Zhen Liu, Min Jiang

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 28, 2024

To assess the circulating characteristics of common respiratory pathogens following complete relaxation non-pharmaceutical interventions (NPIs) and cessation dynamic zero-COVID policy. The retrospective analysis was conducted from 14,412 patients with acute infections (ARIs) January 24, 2020, to December 31, 2023, including Influenza A virus (IFV-A), B (IFV-B), Respiratory Syncytial Virus (RSV), Human Rhinovirus (HRV), Parainfluenza (HPIV), Metapneumovirus (HMPV), Coronavirus (HCoV), Bocavirus (HBoV), Adenovirus (HAdV), Mycoplasma pneumoniae (MP). Compared 2020–2022, Joinpoint indicated a monthly increase in overall pathogen activity rising an average 43.05% 68.46%. positive rates IFV-A, IFV-B, HMPV, HPIV, HCoV, MP increased, while those HRV RSV decreased, no differences HAdV HBoV. outbreak IFV-A observed, rate has surpassed pre-COVID-19 pandemic levels spread interrupted by IFV-A. Infants toddlers were primarily infected RSV, Children adolescents exhibited higher prevalence MP, HRV, whereas Adults elderly incidence co-infections rose 4.25 13.73%. Restricted cubic spline models showed that susceptible age ranges for multiple expanded. These changes serve as reminder stay alert future offer clinicians useful guide diagnosing treating.

Language: Английский

Citations

2
Seasonal Shifts in Influenza, Respiratory Syncytial Virus, and Other Respiratory Viruses After the COVID-19 Pandemic: An Eight-Year Retrospective Study in Jalisco, Mexico DOI Creative Commons

Ernestina Quintero-Salgado,

Jaime Briseño-Ramírez,

Gabriel Vega‐Cornejo

et al.

Viruses, Journal Year: 2024, Volume and Issue: 16(12), P. 1892 - 1892

Published: Dec. 8, 2024

The coronavirus disease 2019 (COVID-19) pandemic profoundly disrupted the epidemiology of respiratory viruses, driven primarily by widespread non-pharmaceutical interventions (NPIs) such as social distancing and masking. This eight-year retrospective study examines seasonal patterns incidence influenza virus, syncytial virus (RSV), other viruses across pre-pandemic, pandemic, post-pandemic phases in Jalisco, Mexico. Weekly case counts were analyzed using an interrupted time series (ITS) model, segmenting timeline into these three distinct phases. Significant reductions circulation observed during followed atypical resurgences NPIs relaxed. Influenza displayed alternating subtype dominance, with A H3 prevailing 2022, B surging 2023, H1N1 increasing thereafter, reflecting potential immunity gaps. RSV activity was marked earlier onset higher intensity post-pandemic. Other including human rhinovirus/enterovirus (HRV/HEV) parainfluenza (HPIV), showed altered dynamics, some failing to return pre-pandemic seasonality. These findings underscore need for adaptive surveillance systems vaccination strategies address evolving viral patterns. Future research should investigate long-term public health implications, focusing on vaccination, clinical outcomes, healthcare preparedness.

Language: Английский

Citations

1
Influenza Viruses Detected in Lethal Cases in the Russian Federation in the 2023–2024 Respiratory Virus Season DOI
N. D. Boldyrev, А. С. Панова, Natalia Kolosova

et al.

ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, Journal Year: 2024, Volume and Issue: unknown, P. 68 - 74

Published: Nov. 1, 2024

Introduction: Influenza is a highly contagious disease which can cause severe complications and even death, particularly in high-risk populations. Continuous monitoring careful testing of seasonal influenza viruses, especially for cases, necessary to develop optimize prevention treatment. Objective: To establish genetic antigenic characteristics viruses detected lethal cases the Russian Federation 2023–2024 respiratory virus season. Materials methods: From September 29, 2023 June 1, 2024, 859 specimens from (nasopharyngeal swabs) 101 autopsy trachea, bronchi, lungs 57 regions were analyzed by PCR. For those with sufficient amount material, whole-genome sequencing was performed using Illumina MiSeq platform. Results: The season characterized dominance A/H3N2 subclade 2a.3a.1. A/H1N1pdm09 type B lesser extent that period. Additional diversification observed during accumulation amino acid substitutions hemagglutinin sites. Most among at high risk unvaccinated. No mutations associated increased pathogenicity virulence identified cases. molecular markers drug resistance neuraminidase inhibitors baloxavir marboxil all tested Conclusion: diseases State Research Center Virology Biotechnology “Vector” similar recovered patients. isolated genetically antigenically vaccine strain had no or resistance.

Language: Английский

Citations

0