Harnessing Mirror Neurons: A New Frontier in Parkinson’s Disease Rehabilitation—A Scoping Review of the Literature

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(15), P. 4539 - 4539

Published: Aug. 2, 2024

: Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Rehabilitation utilizing mirror neurons leverages the brain's capacity for action observation (AO) imagery (MI) to enhance function. This approach involves patients imitating movements observed in therapists or videos, aiming improve gait, coordination, overall quality of life. Mirror neuron activation facilitates learning may decelerate progression, thus enhancing patient mobility independence.

Language: Английский

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Identification of Cognitive Training for Individuals with Parkinson’s Disease: A Systematic Review

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(1), P. 61 - 61

Published: Jan. 11, 2025

Background/Objectives: Parkinson’s disease (PD) is a neurodegenerative disorder, characterised by cardinal motor features and multitude of non-motor manifestations. Among them, cognitive impairment in PD has been recognised as defined clinical entity, it might lead to an increased risk developing dementia. Consequently, the present review aimed ascertain available interventions for training abilities persons with (PwPD). Methods: PRISMA guidelines were followed select studies following databases: PubMed, PsycINFO, Web Science. Two independent reviewers conducted different phases review, third expert was called address any doubts/conflicts. Randomised controlled trials randomised concerning outcomes PwPD selected. Results: A total 28 articles included. The considered applied various experimental functions PwPD: computer-based platforms, exergames, paper-and-pencil programmes, dual-task or treadmill action observation therapy, imagery, virtual reality components, targeting precise domain, tele-rehabilitation, transcranial direct current stimulation, structured training, multimodal treatments. Cognitive assessed employing neuropsychological tests, self-report questionnaires, computerised batteries. Conclusions: Overall, reported better performances groups compared control groups, several domains. Structured emerged most effective strategy enhance functioning PwPD. However, further are necessary determine appropriate useful develop that also consider patients’ quality life.

Language: Английский

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A scoping review on motor imagery-based rehabilitation: Potential working mechanisms and clinical application for cognitive function and depression

Clinical Rehabilitation, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Objective To map evidence on the characteristics, effectiveness, and potential mechanisms of motor imagery interventions targeting cognitive function depression in adults with neurological disorders and/or mobility impairments. Data Sources Six English databases (The Cochrane Library, PubMed, Embase, Scopus, Web Sciences, PsycINFO), two Chinese (CNKI WanFang), a gray literature database were searched from inception to December 2024. Review Methods This scoping review followed Joanna Briggs Institute Scoping methodology. Interventional studies that evaluated for impairments included. Results A total 24 studies, primarily involving cerebrovascular diseases, multiple sclerosis, Parkinson's disease, identified. Motor was typically conducted at home/clinic, occurring 2 3 sessions per week approximately months, each session lasting 20 30 minutes. The 62.5% (n = 10) reported significant improvements function, exhibiting moderate-to-large effect sizes (Cohen's d 0.48–3.41), especially memory, attention, executive while 53.3% 8) indicated alleviation −0.72– −2.56). could relieve pain perception promote beneficial changes brains by facilitating neurotrophic factor expression activating neural circuits related motor, emotional, functions. Conclusion feasibly be home, promising effects depression. More high-quality randomized controlled trials neuroimaging techniques are needed investigate neuroplasticity brain functional reorganization, thereby aiding development mechanism-driven interventions.

Language: Английский

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Gait physiotherapy with motor imagery in people with Parkinson’s disease: a protocol for randomized control GAITimagery trial

Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 17, 2025

According to people with Parkinson's disease (PD), gait impairments are the most disabling motor symptoms of PD. Recently, imagery (MI) has gained notoriety as a training technique due flexibility its use, however, it not been demonstrated that causes superior effect when included in physiotherapy. This study aims determine if combined MI greater on PD than just training. The GAITimagery is designed double-blind, randomized control trial, including convenience sample 2 parallel groups (1:1) two interventions sessions per week during 6-week and 8-week follow-up. initial recruitment will be 88 participants idiopathic unimpaired cognition state, who randomly divided into groups: (GiG) or active Gait group (GaG). Both perform same exercises but only GiG include speed primary outcome, while Maximum (m/s) variability secondary results. tertiary outcomes related Quality life, Daily life activities, Freezing gait, Balance, Mobility, performance measures psychometrics biomechanics instruments. All results measured at baseline (t0), post-training (t1), follow-up assessment (t2) 8 weeks after finished physiotherapy programs. program standardizes application improvement parkinsonian time monitoring vividness referred by session session. effectiveness this MI-exclusive includes subjective objective measurement tools detect minimal changes still-to-be-finish support therapeutic decisions whether allocate depending size achieved comparison

Language: Английский

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Inertial-based dual-task gait normalcy index at turns: a potential novel gait biomarker for early-stage Parkinson’s disease

IEEE Transactions on Neural Systems and Rehabilitation Engineering, Journal Year: 2025, Volume and Issue: 33, P. 687 - 695

Published: Jan. 1, 2025

As one of the main motor indicators Parkinson's disease (PD), postural instability and gait disorder (PIGD) might manifest in various but subtle symptoms at early stage resulting relatively high misdiagnosis rate. Quantitative assessment under dual task or complex (i.e., turning) may contribute to better understanding PIGD provide a diagnostic indicator early-stage PD. However, few studies have explored deviation evaluation algorithms that reflect specificity. In this work, we proposed novel inertial-based normalcy index (GNI) based on quantitative model characterize overall performance during both straight walking turning with without serial-3 subtraction task. The factor group GNI variable was investigated feasibility improve PD validated. experimental results showed paradigm is significant where dual-task turn had best discriminating ability between HC (AUC = 0.992) significantly correlated UPDRS III (r 0.81), MMSE(r 0.57) Mini-BEST(r 0.65). We also observed turning-based has larger effect size compared clinical scales, demonstrating can changes functional mobility rehabilitation for Our work offers an innovative potential biomarker diagnostics provides new perspective into its application

Language: Английский

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Balance Exercise Interventions in Parkinson's Disease: A Systematic Mapping Review of Components, Progression, and Intensity

Parkinsonism & Related Disorders, Journal Year: 2025, Volume and Issue: unknown, P. 107310 - 107310

Published: Jan. 1, 2025

Language: Английский

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Effectiveness of Therapies Based on Mirror Neuron System to Treat Gait in Patients with Parkinson’s Disease—A Systematic Review

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(14), P. 4236 - 4236

Published: July 21, 2022

Parkinson's disease (PD) is a neurodegenerative that alters gait patterns from early stages. The visuo-motor training strategies such as action observation (AO) and motor imagery (MI) are based on the activity of mirror neuron system (MNS) facilitate re-learning. main purpose this systematic review was to analyze current scientific evidence about effectiveness MNS's treatments (AO MI) treat in patients with PD. Searches were completed databases PubMed, Web Science, PEDro between November December 2021. following keywords used: "Parkinson disease", "mirror neurons", "gait", "action observation", "motor imagery". Randomized control trials last 5 years written English or Spanish included. Two independent reviewers screened articles applied eligibility criteria, third reviewer assisted process. A total six included for final revision. risk bias assessed Scale. effects AO MI using different outcome measures referenced terms severity, quality life, balance, gait. Training effective improving

Language: Английский

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Benefits of dance for Parkinson’s: The music, the moves, and the company

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(11), P. e0265921 - e0265921

Published: Nov. 21, 2022

Dance classes designed for people with Parkinson’s are very popular and associated not only increasing individuals’ motor control abilities but also their mood; least by providing a social network the enjoyment of music. However, quantitative evidence benefits is inconsistent often lacks in power. For better understanding contradictory findings between participants’ felt experiences existing response to dance classes, we employed mixed method approach that focussed on effects Participant experience class was explored means semi-structured interviews gait changes were measured within-subjects design through Timed Up Go (TUG) test before after class, without We chose TUG its ecological validity, as it simple resembles movements done class. hypothesised music would have facilitating effect performance. In line research, found 26 participants significantly improved when accompanied soundtrack. did effect, yet compared before. suggest whilst acts an external stimulator movement internalised or rhythm supports control. Thus, externally played less relevance. The importance further emphasised qualitative data alongside themes. A how affects symptoms what aspects make individuals ‘feel better’ will help future interventions.

Language: Английский

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Cognitive approaches in the rehabilitation of upper limbs function in children with cerebral palsy: a systematic review and meta-analysis

European Journal of Physical and Rehabilitation Medicine, Journal Year: 2024, Volume and Issue: 60(3)

Published: March 21, 2024

Cerebral palsy (CP) is the predominant cause of children disability. It characterized by motor, sensory, and postural deficits due to a non-progressive injury developing central nervous system. In recent years, new rehabilitation techniques targeting representations motor patterns have been introduced: most used are action observation therapy (AOT), imagery (MI), mirror (MT). Aim this study assess effectiveness these cognitive strategies on recovery upper limb functions in with CP.

Language: Английский

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Effectiveness of Motor Imagery in the Rehabilitation of People With Parkinson’s Disease: A Systematic Review and Meta-Analysis

Neurorehabilitation and neural repair, Journal Year: 2024, Volume and Issue: 38(6), P. 460 - 475

Published: April 30, 2024

With more research completed using Motor imagery (MI) in people with Parkinson's disease, this study gathered and synthesized evidence on the use of MI for disease improving rehabilitation outcomes.

Language: Английский

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