Sports and Exercise Medicine - Open Journal,
Journal Year:
2023,
Volume and Issue:
9(1), P. 1 - 8
Published: Dec. 29, 2023
Background
Fatigue
decreases
exercise
performance,
and
affects
work
capacity
quality
of
life.
Functional
supplement
use
is
one
the
common
methods
to
alleviate
fatigue.
Rhodiola
rosea
(RHR)
exerts
antioxidative
anti-inflammatory
effects
due
its
rich
glycosides
has
potential
resist
Therefore,
this
study
aims
investigate
RHR
on
physical
fatigue
induced
by
exhaustive
swimming
exercise.
Methods
Forty
institute
cancer
research
(ICR)
mice
were
divided
assigned
four
treatment
groups
(0,
600,
1200,
3000
mg/kg
body
weight),
with
10
animals
in
each
group.
After
weeks
intervention,
tests
conducted
assess
endurance,
accumulation
blood
markers,
tissue
glycogen
storage.
Results
The
results
showed
that
after
time
significantly
increased
three
a
dose-dependence
effect.
substances
(lactate,
urea
nitrogen
(BUN),
creatine
kinase
(CK)
was
decreased,
content
liver
muscle
elevated.
Conclusion
supplements
possess
enhance
performance
prevent
exercise-induced
It
suitable
develop
an
as
dietary
for
anti-fatigue.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(16), P. 2657 - 2657
Published: Aug. 11, 2024
Irritable
bowel
syndrome
(IBS)
is
a
prevalent
functional
gastrointestinal
disorder
characterized
by
abdominal
pain,
bloating,
diarrhea,
and
constipation.
Recent
studies
have
underscored
the
significant
role
of
gut
microbiota
in
pathogenesis
IBS.
Physical
exercise,
as
non-pharmacological
intervention,
has
been
proposed
to
alleviate
IBS
symptoms
modulating
microbiota.
Aerobic
such
running,
swimming,
cycling,
shown
enhance
diversity
abundance
beneficial
bacteria,
including
Lactobacillus
Bifidobacterium.
These
bacteria
produce
short-chain
fatty
acids
that
possess
anti-inflammatory
properties
support
barrier
integrity.
Studies
involving
patients
participating
structured
aerobic
exercise
programs
reported
improvements
their
microbiota's
composition
diversity,
alongside
an
alleviation
like
pain
bloating.
Additionally,
positively
influences
mental
health
reducing
stress
improving
mood,
which
can
further
relieve
via
gut-brain
axis.
Long-term
interventions
provide
sustained
benefits,
maintaining
stability,
supporting
immune
functions,
systemic
inflammation.
However,
must
be
tailored
individual
needs
avoid
exacerbating
symptoms.
Personalized
plans
starting
with
low-to-moderate
intensity
gradually
increasing
maximize
benefits
minimize
risks.
This
review
examines
impact
various
types
intensities
physical
on
patients,
highlighting
need
for
explore
optimal
protocols.
Future
research
should
include
larger
sample
sizes,
longer
follow-up
periods,
examine
synergistic
effects
other
lifestyle
modifications.
Integrating
into
comprehensive
management
symptom
control
improve
patients'
quality
life.
Journal of Food Science,
Journal Year:
2024,
Volume and Issue:
89(4), P. 2465 - 2481
Published: Feb. 21, 2024
Camellia
seed
oil
(CO)
has
high
nutritional
value
and
multiple
bioactivities.
However,
the
specific
anti-fatigue
characteristics
implied
mechanism
of
CO
have
not
yet
been
fully
elucidated.
Throughout
this
investigation,
male
C57BL/6J
mice,
aged
8
weeks,
underwent
exhaustive
exercise
with
or
without
pretreatment
(2,
4,
6
mL/kg
BW)
for
28
days.
could
extend
rota-rod
running
time,
reduce
blood
urea
nitrogen
levels
serum
lactic
acid,
increase
muscle
hepatic
glycogen,
adenosine
triphosphate,
anti-oxidative
indicators.
Additionally,
upregulate
mRNA
Nrf2
protein
expression
levels,
as
well
enhance
its
downstream
antioxidant
enzymes
induce
myofiber-type
transformation
from
fast
to
slow
attenuate
gut
mechanical
barrier.
Moreover,
ameliorate
dysbiosis
by
reducing
Firmicutes
Bacteroidetes
ratio
at
phylum
level,
increasing
percentage
Alistipes,
Alloprevotella,
Lactobacillus,
Muribaculaceae,
decreasing
proportion
Dubosiella
genus
level.
In
addition,
bacterial
taxa,
which
were
altered
CO,
showed
a
significant
correlation
partial
fatigue-related
parameters.
These
findings
suggest
that
may
alleviate
fatigue
regulating
capacity,
fiber
transformation,
barrier,
microbial
composition
in
mice.
PRACTICAL
APPLICATION:
Our
study
revealed
camellia
exercise-induced
mice
modulating
fiber,
results
promote
application
an
functional
food
targets
oxidative
stress,
community.
Scope
Urolithin
A
(UA),
a
gut‐microbiota‐derived
metabolite
of
ellagic
acid,
presents
various
benefits
to
intestinal
microecology.
The
presence
“gut‐muscle
axis”
regulating
the
onset
and
progression
exercise‐related
physical
frailty
sarcopenia
has
been
recently
hypothesized.
This
study
aims
explore
underlying
mechanism
gut‐muscle
axis
by
which
UA
enhances
muscle
strength
fatigue
resistance
sleep‐deprived
(SD)
mice.
Methods
results
is
gavaged
C57BL/6
mice
(50
mg
kg
−1
bw)
before
48‐h
SD.
indicate
that
pretreatment
significantly
motor
ability
energy
metabolism.
inflammation
suppressed,
permeability
improved
after
prophylactic
treatment
with
UA.
decreased
level
serum
lipopolysaccharide
(LPS)
concomitant
augmentation
tight
junction
proteins.
16s
rRNA
analysis
colonic
contents
reveals
reduces
abundance
Clostridia_UCG‐014
Candidatus_Saccharimonas
,
upregulates
Lactobacillus
Muribaculaceae
.
probably
influences
on
gut
microbial
functions
via
several
metabolism
pathways,
such
as
carbon
metabolism,
phosphotransferase
system
(PTS),
ATP
binding
cassette
(ABC)
transporters.
Conclusions
dietary
intervention
helps
create
systemic
protection,
bidirectional
communication
connecting
microbiota
system,
able
alleviate
SD‐induced
mobility
impairment
dysbiosis.
Phytochemistry Reviews,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 27, 2024
Abstract
The
challenge
of
antimicrobial
resistance
requires
new
solutions,
and
Rhodiola
sp.
is
a
promising
candidate
due
to
its
rich
medicinal
history.
This
review
focuses
on
sp.,
especially
R.
rosea
,
highlighting
phytochemical
constituents,
such
as
salidroside,
rosavins,
other
phenolics,
their
potential.
We
investigate
the
efficacy
against
various
pathogenic
bacteria,
suggesting
value
in
combating
resistance.
Additionally,
compounds
are
being
investigated
both
direct
antimicrobials
modifiers
that
increase
antibiotics.
extracts
salidroside
modulate
gut
microbiota,
thereby
affecting
health
physiological
metabolic
disorders.
illustrates
comprehensive
therapeutic
potential
emphasize
importance
understanding
complex
interactions
between
phytochemicals,
effects,
effects
microbiota
well
need
for
in-depth
research.
Further
studies
will
be
crucial
development
holistic
treatment
approaches.
Finally,
highlighted
an
important
natural
resource
fight
microbial
pathogens
antibiotic
Research
should
continue
further
unravel
pharmacological
health-promoting
thus
address
public
challenge.
