Polymers for Advanced Technologies,
Journal Year:
2022,
Volume and Issue:
34(1), P. 6 - 23
Published: Oct. 4, 2022
Abstract
Electrospinning
procedures
such
as
blend
electrospinning,
coaxial
and
emulsion
electrospinning
have
been
used
for
the
fabrication
of
electrospun
nanofibers
(ENFs)
biomedical
applications.
These
ENFs
are
attracted
great
interest
especially
in
drug
delivery
applications
due
to
their
small
size,
high
surface
area‐to‐volume,
porosity.
The
aim
this
review
is
focus
on
controlled
release
mechanism
among
different
methods,
selectivity
hydrophilic,
water‐soluble
polymers
a
carrier
drug.
depends
mainly
method
loading,
polymeric
interactions,
nature
polymer
swelling,
erosion,
or
degradation.
This
compressed
literature
survey
about
by
factors
affecting
nanofiber
morphologies,
blends
successful
behavior,
involved
steps.
Journal of Biological Engineering,
Journal Year:
2023,
Volume and Issue:
17(1)
Published: March 20, 2023
Abstract
As
an
emerging
science,
tissue
engineering
and
regenerative
medicine
focus
on
developing
materials
to
replace,
restore
or
improve
organs
tissues
enhancing
the
cellular
capacity
proliferate,
migrate
differentiate
into
different
cell
types
specific
tissues.
Renewable
resources
have
been
used
develop
new
materials,
resulting
in
attempts
produce
various
environmentally
friendly
biomaterials.
Poly
(lactic
acid)
(PLA)
is
a
biopolymer
known
be
biodegradable
it
produced
from
fermentation
of
carbohydrates.
PLA
can
combined
with
other
polymers
biomaterials
suitable
physicochemical
properties
for
applications.
Here,
advances
modified
as
are
discussed
light
its
drawbacks,
such
biological
inertness,
low
adhesion,
degradation
rate,
efforts
conducted
address
these
challenges
toward
design
enhanced
alternative
Giant,
Journal Year:
2024,
Volume and Issue:
18, P. 100261 - 100261
Published: April 4, 2024
Polylactic
Acid
(PLA)
is
a
biodegradable
polymer
gaining
popularity
as
replacement
for
conventional
plastics
in
different
industrial
sectors.
However,
PLA
has
inherent
limitations
and
requires
modifications
to
enhance
its
performance.
This
review
article
covers
the
important
aspects
related
such
synthesis
route
of
PLA,
biodegradation
mechanism
properties
applications
The
main
focus
this
identify
innovative
copolymers,
blends
composites
biomedical
applications.
Most
characteristics
degradation
behavior,
biocompatibility
mechanical
these
PLA-based
polymers
were
briefly
discussed.
indicates
that
optimization
processing
techniques
suitable
selection
additives
play
an
role
achieve
desired
PLA.
also
discusses
issues
associated
materials
Journal of Materials Chemistry B,
Journal Year:
2023,
Volume and Issue:
11(40), P. 9597 - 9629
Published: Jan. 1, 2023
Polyesters
based
on
polyols
have
emerged
as
promising
biomaterials
for
various
biomedical
applications,
such
tissue
engineering
and
drug
delivery
systems,
due
to
their
biocompatibility,
biodegradability,
versatile
physicochemical
properties.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(9)
Published: Sept. 1, 2024
Abstract
Graphene
quantum
dots
(GQDs),
owing
to
their
unique
optical,
electrical,
and
chemical
properties,
have
emerged
as
promising
nanomaterials
for
various
biomedical
applications.
This
review
provides
a
comprehensive
overview
of
the
latest
advancements
in
utilization
GQDs
tissue
engineering,
wound
healing,
drug
delivery
systems,
other
therapies.
The
inherent
properties
GQDs,
including
high
biocompatibility,
tunable
photoluminescence,
significant
surface
area,
make
them
ideal
candidates
enhancing
medical
treatments
diagnostics.
In
improve
mechanical
biological
performance
scaffolds,
promoting
cell
proliferation
differentiation.
For
enhance
antimicrobial
activity
facilitate
faster
regeneration.
Their
potential
DDS
is
highlighted
by
ability
deliver
therapeutic
agents
efficiently,
ensuring
targeted
controlled
release.
Additionally,
play
crucial
role
therapies,
particularly
cancer
treatment,
efficacy
reducing
side
effects.
While
offer
diagnostics,
challenges
such
understanding
long‐term
cytotoxicity
at
higher
concentrations,
need
standardized
synthesis
methods
remain
critical
areas
further
research.
also
discusses
future
directions
opportunities
emphasizing
transformative
advancing
modern
healthcare
solutions.
insights
presented
here
contribute
expanding
field
GQD
research,
highlighting
significantly
patient
outcomes
drive
innovations.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(10)
Published: Oct. 1, 2024
ABSTRACT
Nanogels
represent
a
significant
innovation
in
the
fields
of
nanotechnology
and
biomedical
engineering,
combining
properties
hydrogels
nanoparticles
to
create
versatile
platforms
for
drug
delivery,
tissue
bioimaging,
other
applications.
These
nanoscale
hydrogels,
typically
ranging
from
10
1000
nm,
possess
unique
characteristics
such
as
high
water
content,
biocompatibility,
ability
encapsulate
both
hydrophilic
hydrophobic
molecules.
The
review
explores
synthesis,
structural
configurations,
stimuli‐responsive
nature
nanogels,
highlighting
their
adaptability
targeted
including
across
challenging
barriers
like
blood–brain
barrier.
Furthermore,
paper
delves
into
applications
particularly
delivery
systems,
demonstrating
potential
revolutionize
these
fields.
Despite
promising
preclinical
results,
challenges
remain
translating
technologies
clinical
practice,
issues
related
stability,
scalability,
regulatory
approval.
concludes
by
discussing
future
perspectives,
emphasizing
need
further
research
optimize
ultimately
aiming
enhance
efficacy
safety
settings.
