How metabolism and development are intertwined in space and time DOI Creative Commons
Camila Caldana, Fernando Carrari, Alisdair R. Fernie

et al.

The Plant Journal, Journal Year: 2023, Volume and Issue: 116(2), P. 347 - 359

Published: July 12, 2023

Developmental transitions, occurring throughout the life cycle of plants, require precise regulation metabolic processes to generate energy and resources necessary for committed growth processes. In parallel, establishment new cells, tissues, even organs, alongside their differentiation provoke profound changes in metabolism. It is increasingly being recognized that there a certain degree feedback between components products pathways developmental regulators. The generation large-scale metabolomics datasets during combination with molecular genetic approaches has helped further our knowledge on functional importance development. this perspective article, we provide insights into studies elucidate interactions metabolism development at temporal spatial scales. We additionally discuss how influences cell growth-related also highlight intermediates function as signaling molecules direct plant response changing internal external conditions.

Language: Английский

Genetic regulation and manipulation of nicotine biosynthesis in tobacco: strategies to eliminate addictive alkaloids DOI Creative Commons
Tsubasa Shoji, Takashi Hashimoto, Kazuki Saito

et al.

Journal of Experimental Botany, Journal Year: 2023, Volume and Issue: 75(6), P. 1741 - 1753

Published: Aug. 30, 2023

Abstract Tobacco (Nicotiana tabacum L.) is a widely cultivated crop of the genus Nicotiana. Due to highly addictive nature tobacco products, smoking remains leading cause preventable death and disease. There therefore critical need develop varieties with reduced or non-addictive nicotine levels. Nicotine related pyridine alkaloids biosynthesized in roots plants are transported leaves, where they stored vacuoles as defense against predators. Jasmonate, defense-related plant hormone, plays crucial signaling role activating transcriptional regulators that coordinate expression downstream metabolic transport genes involved production. In recent years, substantial progress has been made molecular genomics research, revealing many regulatory biosynthesis. These advances have enabled us low ultra-low levels through various methodologies, such mutational breeding, genetic engineering, genome editing. We review on manipulation production tobacco, which serves an excellent example engineering profound social implications.

Language: Английский

Citations

14
Adaptable Alchemy: Exploring the Flexibility of Specialized Metabolites to Environmental Perturbations Through Post-Translational Modifications (PTMs) DOI Creative Commons
Luca Cimmino, Annalisa Staiti, Domenico Carputo

et al.

Plants, Journal Year: 2025, Volume and Issue: 14(3), P. 489 - 489

Published: Feb. 6, 2025

Plants are subjected to various stresses during the growth process, including biotic stresses, as well abiotic such temperature, drought, salt, and heavy metals. To cope with these adversities, plants have evolved complex regulatory mechanisms their long-term environmental adaptations. In a suddenly changing environment, protein modifiers target other proteins induce post-translational modification (PTM) in order maintain cell homeostasis biological activity plants. PTMs modulate of enzymes transcription factors respective metabolic pathways, enabling produce essential compounds for survival under stress conditions. Examples include phosphorylation, ubiquitination, glycosylation, acetylation, protein–protein interactions, targeted degradation. Furthermore, role histone modifications regulating secondary metabolism deserves attention due its potential impact on heritability contribution tolerance. Understanding epigenetic aspect can provide valuable insights into underlying response. this context, also examining that biosynthesis metabolites is meaningful. Secondary encompass wide range flavonoids, alkaloids, terpenoids. These play crucial plant defense against herbivores, pathogens, oxidative stress. it imperative understand tolerance how understanding be leveraged improve survival. While many studies focused transcriptional regulation metabolites, there growing interest changes PTMs, able plants’ response conclusion, comprehensive exploration enhance our responses This knowledge holds promise future applications genetic improvement breeding strategies aimed at increasing resilience challenges.

Language: Английский

Citations

0
Revolutionizing Speciality teas: Multi-omics prospective to breed anthocyanin-rich tea DOI

S. M. Yadav,

Mohammed Saba Rahim, Amna Devi

et al.

Food Research International, Journal Year: 2025, Volume and Issue: unknown, P. 116312 - 116312

Published: March 1, 2025

Language: Английский

Citations

0
Production, Utilization, and Breeding of Winter Rye DOI
Tesfaye Walle Mekonnen, Maryke Labuschagne

Published: Jan. 1, 2025

Language: Английский

Citations

0
Plant biochemical genetics in the multiomics era DOI Creative Commons
Saleh Alseekh, Esra Karakaş, Feng Zhu

et al.

Journal of Experimental Botany, Journal Year: 2023, Volume and Issue: 74(15), P. 4293 - 4307

Published: May 12, 2023

Our understanding of plant biology has been revolutionized by modern genetics and biochemistry. However, biochemical can be traced back to the foundation Mendelian genetics; indeed, one Mendel's milestone discoveries seven characteristics pea plants later came ascribed a mutation in starch branching enzyme. Here, we review both current historical strategies for elucidation metabolic pathways genes that encode their component enzymes regulators. We use this discuss range classical genetic phenomena including epistasis, canalization, heterosis as viewed through lens contemporary high-throughput data obtained via array approaches currently adopted multiomics studies.

Language: Английский

Citations

6
How metabolism and development are intertwined in space and time DOI Creative Commons
Camila Caldana, Fernando Carrari, Alisdair R. Fernie

et al.

The Plant Journal, Journal Year: 2023, Volume and Issue: 116(2), P. 347 - 359

Published: July 12, 2023

Developmental transitions, occurring throughout the life cycle of plants, require precise regulation metabolic processes to generate energy and resources necessary for committed growth processes. In parallel, establishment new cells, tissues, even organs, alongside their differentiation provoke profound changes in metabolism. It is increasingly being recognized that there a certain degree feedback between components products pathways developmental regulators. The generation large-scale metabolomics datasets during combination with molecular genetic approaches has helped further our knowledge on functional importance development. this perspective article, we provide insights into studies elucidate interactions metabolism development at temporal spatial scales. We additionally discuss how influences cell growth-related also highlight intermediates function as signaling molecules direct plant response changing internal external conditions.

Language: Английский

Citations

3