Post-COVID-19 Epidemiology of Bronchiolitis: We Are (Not) Returning to the Past

The Pediatric Infectious Disease Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 14, 2025

To the Editors: In 2024, Pediatric Infectious Disease Journal presented findings of an Italian study analyzing how coronavirus disease 2019 (COVID-19) pandemic influenced viral bronchiolitis' characteristics.1 The authors recommended that hospitals maintain a high level surveillance epidemiological changes to ensure prompt response and proper allocation resources. Considering profound impact bronchiolitis epidemiology modifications in our setting,2,3 these observations prompted us monitor admissions during 2023–2024 epidemic season continue describing trends we have already reported since before start pandemic.2,3 For this purpose, included all children 0–2 years with International Classification Diseases, 9th revision diagnosis admitted Istituto Gaslini, Italy, from 1 October 2023 30 April 2024 compared previous 6 seasons. region, typically followed seasonal pattern prepandemic era, starting December, peaking January February, decreasing spring.2 These been drastically disrupted by COVID-19 related preventive interventions resulting disappearance year 2020–2021. 2021–2022 season, after relaxation pandemic-related measures, huge significantly early peak was detected, gradual shift curve 2022–2023 always increased although less anticipated peak. last hospitalizations distribution seemed be realigning late November, December January, ending spring, thus suggesting possible "return past" (Fig. 1A).FIGURE 1.: Trend seasons (1 October–30 April) 2017–2024 period at Gaslini Institute, Genoa, Italy (A) corresponding absolute numbers, annual rate per 1000 prevalence RSV 100 tested (B). indicates respiratory syncytial virus.However, total remained largely over 300, three times more than years. admission for 7.7 20 × 1B), absence rising regional birth rates,4 incidence ratio being 2.7 (95% confidence interval: 2.1–3.3, P < 0.001) higher 2017–2018 season. Although temporal seems resemble trend were used to, appears persistently enhanced. reason phenomenon is not easily understandable. A partial explanation could found virus, which went cause 50–60% 70–80% postpandemic era. This reflect reduced population exposure viruses pandemic, vulnerability among infants susceptibility sustained circulation virus also support supposed severity years.5 conclusion, transition beginning observed, setting burden overwhelming universal prevention measures available other countries. Close monitoring remains crucial fully understand long-term effects assess hopefully significant prophylaxis.

Language: Английский

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Seasonality and severity of respiratory syncytial virus during the COVID-19 pandemic: a dynamic cohort study

International Journal of Infectious Diseases, Journal Year: 2024, Volume and Issue: 148, P. 107231 - 107231

Published: Sept. 1, 2024

Language: Английский

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Severe bronchiolitis before and after the COVID-19 pandemic: a retrospective database analysis by the Italian Network of PICU study group (TIPNet)

Journal of Anesthesia Analgesia and Critical Care, Journal Year: 2024, Volume and Issue: 4(1)

Published: Nov. 26, 2024

Abstract Background The first post-COVID-19 pandemic year demonstrated an unusual bronchiolitis epidemic in both hemispheres and has been attributed to the removal of barriers implemented during SARS-CoV-2 infection. Several countries reported increase respiratory syncytial virus (RSV) bronchiolitis, with more hospitalizations a greater need for support. We aimed evaluate consequences COVID-19 on epidemiology management severe pediatric intensive care units (PICUs) Italy. Methods Multicenter, retrospective, cohort database analysis. All children younger than 24 months admitted 7 PICUs from October 2017 April 2023 diagnosed were included. compared patients pre-COVID post-COVID eras, excluding 2020–2021 season due low numbers. Logistic regression models used assess impact pre-/post-COVID period invasive ventilation. Results Seven hundred fifteen PICU study period, 451 251 post-COVID. Patients group older, had comorbidities, higher Pediatric Index Mortality scores at admission but support was not significantly different. There high variability across centers. Presenting protective against risk mechanical ventilation, adjusted age disease severity (OR 0.38, 95% CI 0.16–0.89), while RSV infection increased intubation 2.49, 1.1–5.63). Conclusions have faced unexpected peak cases after pandemic, which did require

Language: Английский

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Changes in entire acute bronchiolitis seasons before, during, and after the COVID-19 pandemic in Spain.

Infection Prevention in Practice, Journal Year: 2024, Volume and Issue: 6(4), P. 100399 - 100399

Published: Sept. 23, 2024

Language: Английский

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Prophylaxis with palivizumab in a six‐year‐old girl with Down syndrome and postinfectious obliterative bronchiolitis

Pediatric Pulmonology, Journal Year: 2024, Volume and Issue: unknown

Published: July 29, 2024

The authors declare no conflicts of interest. data are available from the corresponding author at this mail address francesca. peri@burlo. trieste. it, upon reasonable request.

Language: Английский

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