Non-nutritive sugar feeding alters the genetic profile of diuretic hormones and their receptors in Drosophila suzukii (Diptera: Drosophilidae)

Annals of the Entomological Society of America, Journal Year: 2025, Volume and Issue: unknown

Published: May 8, 2025

Abstract Non-nutritive sugars such as erythritol and sucralose are active ingredients in artificial sweeteners. In the past decade, research has demonstrated insecticidal properties of non-nutritive across several arthropod species. It is now a prospective chemical control option for spotted-wing drosophila, Drosophila suzukii, one most economically important pests small fruits. D. suzukii die quicker, excrete waste large amounts, become desiccated when fed mixture sucralose. The toxicity to fly not clearly elucidated but likely due nutritional physiological failures associated with an excess fluid excretion water imbalance, caused hyperosmotic body. diuretic processes insects primarily regulated by 3 neuropeptides: CAPA hormone, hormone 31 (DH31), 44 (DH44). To explore genetic effects on we investigated regulation key genes—capa, dh31, dh44—and their 7 corresponding receptors under different dietary conditions: + sucrose, Molecular analyses revealed that expression levels capa, dh44, were significantly altered sugar-fed flies compared group only sucrose. Through trials testing synergistic peptide injection sugar consumption, DH44 consistently increased mortality all diet groups. These findings offer molecular insights development novel pest management strategies targeting suzukii.

Language: Английский

Re‐evaluation of erythritol (E 968) as a food additive

EFSA Journal, Journal Year: 2023, Volume and Issue: 21(12)

Published: Dec. 1, 2023

Abstract This opinion addresses the re-evaluation of erythritol (E 968) as food additive and an application for its exemption from laxative warning label requirement established under Regulation (EU) No 1169/2011. Erythritol is a polyol obtained by fermentation with Moniliella pollinis BC or megachiliensis KW3-6, followed purifications drying. readily dose-dependently absorbed in humans can be metabolised to erythronate small extent. then excreted unchanged urine. It does not raise concerns regarding genotoxicity. The dataset evaluated consisted human interventional studies. Panel considered that has potential cause diarrhoea humans, which was adverse because association electrolyte water imbalance. lower bound range no observed effect levels (NOAELs) 0.5 g/kg body weight (bw) identified reference point. appropriate set numerical acceptable daily intake (ADI) at level An ADI bw per day protective immediate well chronic effects, secondary diarrhoea. highest mean 95th percentile exposure children (742 mg/kg day) adolescents (1532 day). Acute maximally 3531 meal 99th percentile. Overall, both dietary assessments overestimation. concluded estimates acute were above ADI, indicating individuals high may risk experiencing effects after single repeated exposure. Concerning new application, available data do support proposal exemption.

Language: Английский

Evaluating potential phytotoxicity of erythritol solution, a novel control method for Drosophila suzukii, in blueberry, cherry, and wild Himalayan blackberry

Crop Protection, Journal Year: 2024, Volume and Issue: unknown, P. 106961 - 106961

Published: Sept. 1, 2024

Language: Английский