High-fiber cookies with bamboo flour and edible flowers: evaluation of structural properties, phenolic content, antioxidant activity and nutritional value.

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117321 - 117321

Published: Jan. 1, 2025

Language: Английский

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Dietary Guidance, Sensory, Health and Safety Considerations When Choosing Low and No-Calorie Sweeteners

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 793 - 793

Published: Feb. 25, 2025

The growing global focus on the adverse health conditions associated with excessive sugar consumption has prompted and policy organizations as well public to take a more mindful approach wellness. In response, food beverage companies have proactively innovated reformulated their product portfolios incorporate low no-calorie sweeteners (LNCSs) viable alternatives sugar. LNCSs offer an effective safe delivering sweetness foods beverages reducing calories intake while contributing enjoyment of eating. objective this paper is enhance understanding segmentation definitions, dietary reduction guidance, front-of-package labeling, taste sensory perception physiology, metabolic efficacy impact, overall safety

Language: Английский

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Scientific Committee guidance on appraising and integrating evidence from epidemiological studies for use in EFSA's scientific assessments

EFSA Journal, Journal Year: 2024, Volume and Issue: 22(7)

Published: July 1, 2024

Abstract EFSA requested its Scientific Committee to prepare a guidance document on appraising and integrating evidence from epidemiological studies for use in EFSA's scientific assessments. The provides an introduction illustrates the typical biases, which may be present different study designs. It then describes key concepts relevant appraisal. This includes brief explanations measures of association, exposure assessment, statistical inference, systematic error effect modification. concept external validity principles studies. customisation appraisal process is explained including tailoring tools assessing risk bias (RoB). Several examples experimental observational using RoB tool are annexed illustrate application approach. latter part this focuses steps integration, first within across streams evidence. With respect characterisation, considers how human can used dose–response modelling with several options being presented. Finally, addresses uncertainty factors characterisation when

Language: Английский

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Ingestion of the Non-Nutritive Sweetener Erythritol, but Not Glucose, Enhances Platelet Reactivity and Thrombosis Potential in Healthy Volunteers

Arteriosclerosis Thrombosis and Vascular Biology, Journal Year: 2024, Volume and Issue: 44(9), P. 2136 - 2141

Published: Aug. 8, 2024

Although artificial and non-nutritive sweeteners are widely used generally recognized as safe by the US European Union regulatory agencies, there have been no clinical trials to assess either long-term cardiovascular disease risks or short-term disease-relevant phenotypes. Recent studies report that fasting plasma levels of erythritol, a commonly sweetener, clinically associated with heightened incident enhance thrombosis potential in vitro animal models. Effects dietary erythritol on phenotypes humans not examined.

Language: Английский

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Refined intake assessment of seven sweeteners via foods and beverages by the Dutch population using branded data

Food Additives & Contaminants Part A, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 23

Published: March 25, 2025

The intake of seven sweeteners (acesulfame K, aspartame, cyclamates, saccharins, steviol glycosides, sucralose (all chronic intake) and erythritol (acute intake)) via foods beverages by the Dutch population was assessed in a refined assessment using branded data (product labels, use levels consumption shares brands) scenarios for brand-loyalty. In general, these below their respective health-based guidance values (HBGVs). Only toddlers high intakes acesulfame cyclamates were around or slightly above HBGV most conservative scenario ('full brand-loyalty, consumers only'). However, all likely overestimated due to assumptions when on presence absent. Improved information, particularly products with contribution sweetener toddlers, is needed further refine assessment. conclusion, no concern population.

Language: Английский

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Re‐evaluation of erythritol (E 968) as a food additive

EFSA Journal, Journal Year: 2023, Volume and Issue: 21(12)

Published: Dec. 1, 2023

Abstract This opinion addresses the re-evaluation of erythritol (E 968) as food additive and an application for its exemption from laxative warning label requirement established under Regulation (EU) No 1169/2011. Erythritol is a polyol obtained by fermentation with Moniliella pollinis BC or megachiliensis KW3-6, followed purifications drying. readily dose-dependently absorbed in humans can be metabolised to erythronate small extent. then excreted unchanged urine. It does not raise concerns regarding genotoxicity. The dataset evaluated consisted human interventional studies. Panel considered that has potential cause diarrhoea humans, which was adverse because association electrolyte water imbalance. lower bound range no observed effect levels (NOAELs) 0.5 g/kg body weight (bw) identified reference point. appropriate set numerical acceptable daily intake (ADI) at level An ADI bw per day protective immediate well chronic effects, secondary diarrhoea. highest mean 95th percentile exposure children (742 mg/kg day) adolescents (1532 day). Acute maximally 3531 meal 99th percentile. Overall, both dietary assessments overestimation. concluded estimates acute were above ADI, indicating individuals high may risk experiencing effects after single repeated exposure. Concerning new application, available data do support proposal exemption.

Language: Английский

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The first case of erythritol-induced anaphylaxis in Europe diagnosed with skin tests and basophil activation tests

Journal of Allergy and Clinical Immunology Global, Journal Year: 2024, Volume and Issue: 3(4), P. 100335 - 100335

Published: Aug. 28, 2024

The use of erythritol as a food sweetener has spread significantly from Japan throughout the world. We describe case severe anaphylaxis due to immediate-type allergy that was diagnosed with

Language: Английский

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Serum Erythritol and Risk of Overall and Cause-Specific Mortality in a Cohort of Men

Nutrients, Journal Year: 2024, Volume and Issue: 16(18), P. 3099 - 3099

Published: Sept. 14, 2024

Erythritol occurs naturally in some fruits and fermented foods, has also been used as an artificial sweetener since the 1990s. Although there have questions studies regarding its potential adverse health effects, association between serum erythritol long-term mortality not evaluated. To examine erythritol's biochemical status risk of overall cause-specific mortality, a prospective cohort analysis was conducted using participants ATBC Study (1985-1993) previously selected for metabolomic sub-studies. The included 4468 participants, among whom 3377 deaths occurred during average 19.1 years follow-up. Serum assayed untargeted, global, high-resolution, accurate-mass platform ultra-high-performance liquid gas chromatography. Cause-specific were identified through Statistics Finland defined by International Classification Diseases. After adjustment confounders, associated with increased (HR = 1.50 [95% CI 1.17-1.92]). We found positive cardiovascular disease 1.86 1.18-2.94]), which stronger heart than stroke 3.03 1.00-9.17] HR 2.06 0.72-5.90], respectively). Cancer positively 1.54 1.09-2.19]). erythritol-overall men ≥ 55 age those diastolic blood pressure 88 mm Hg (

Language: Английский

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P20-26 Re-evaluation of erythritol (E 968) as a food additive

Toxicology Letters, Journal Year: 2024, Volume and Issue: 399, P. S303 - S304

Published: Sept. 1, 2024

Language: Английский

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