Thiazole and Isothiazole Chemistry in Crop Protection DOI
Jiaxin Wang,

Anjing Liao,

R. Guo

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 73(1), P. 30 - 46

Published: Dec. 27, 2024

Thiazole and isothiazole are types of five-membered heterocycles that contain both sulfur nitrogen atoms. They have gained attention in the field green pesticide research due to their low toxicity, strong biological activity, ability undergo diverse structural modifications. By incorporating thiazole groups into various compounds, researchers been able create a wide range pesticides with broad-spectrum effectiveness. Understanding relationship between structure these compounds activities is crucial for development new highly potent pesticides. This review highlights derivatives aims inspire innovative based on structures.

Language: Английский

Pyrazole derivatives: Recent advances in discovery and development of pesticides DOI
Tingting Du, Siyu Lu,

Zongnan Zhu

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 110912 - 110912

Published: Feb. 1, 2025

Language: Английский

Citations

1
Synthesis and modification of novel thiazole-fused quinoxalines as new insecticidal agents against the cotton leafworm Spodoptera litura: design, characterization, in vivo bio-evaluation, toxicological effectiveness, and study their mode of action DOI Creative Commons
Doaa M. Elsisi,

Moustafa S. Abusaif,

Eman El-Said

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(2), P. 1391 - 1406

Published: Jan. 1, 2025

New insecticidal agents based on quinoxaline derivatives targeting the cotton leafworm, Spodoptera litura .

Language: Английский

Citations

0
Design, Synthesis, and Herbicidal Activities of N-(5-(3,5-Methoxyphenyl)-(thiazole-2-yl))phenoxyacetamide Derivatives DOI
Na Liu,

Yuanhui Wan,

Zhendong Bai

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(42), P. 23097 - 23107

Published: Aug. 13, 2024

Thiazole and phenoxyacetic acid are key moieties in many natural synthetic biologically active agents. A series of

Language: Английский

Citations

3
Discovery of Novel Isoxazoline Derivatives Containing Pyrazolamide Fragment as Insecticidal Candidates DOI

Shaochen Li,

Guangpeng Wang, Yanyang Zhang

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Lepidopteran species cause significant harm to agricultural yields and food quality. In this study, a series of innovative isoxazoline derivatives incorporating pyrazolamide moieties were carefully designed synthesized as potential insecticidal agents. Among these, compound F16 demonstrated an LC50 value 0.01 mg/L against Plutella xylostella, surpassing that the lead fluxametamide (LC50 = 0.15 mg/L). Furthermore, exhibited broad-spectrum activity Pyrausta nubilalis, Spodoptera frugiperda, Chilo suppressalis, Aphis craccivora, Sogatella furcifera. Notably, possessed low toxicity Danio rerio, whereas displayed moderate toxicity. molecular docking analysis potent is likely mediated by its specific interactions with γ-GABA receptors primarily through formation hydrogen bonds key residues. Density functional theory calculations electrostatic potentials also performed gain insights into behavior F16. These findings suggest promising candidate for further investigation novel pesticide.

Language: Английский

Citations

0
Thiazole and Isothiazole Chemistry in Crop Protection DOI
Jiaxin Wang,

Anjing Liao,

R. Guo

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 73(1), P. 30 - 46

Published: Dec. 27, 2024

Thiazole and isothiazole are types of five-membered heterocycles that contain both sulfur nitrogen atoms. They have gained attention in the field green pesticide research due to their low toxicity, strong biological activity, ability undergo diverse structural modifications. By incorporating thiazole groups into various compounds, researchers been able create a wide range pesticides with broad-spectrum effectiveness. Understanding relationship between structure these compounds activities is crucial for development new highly potent pesticides. This review highlights derivatives aims inspire innovative based on structures.

Language: Английский

Citations

1