Effect of the number of coronavirus disease 2019 (COVID-19) vaccination shots on the occurrence of pneumonia, severe pneumonia, and death in SARS-CoV-2-infected patients

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 8, 2024

Background Coronavirus disease (COVID-19) has posed a significant threat to the lives and health of people worldwide since its onset in 2019. However, relationship between number vaccination shots severity SARS-CoV-2 infection Chinese patients remains unclear. Methods We retrospectively collected information from 829 infected with Ningbo Medical Center Lihuili Hospital December 05, 2022 March 31, 2023, then divided them into four groups based on pneumonia. Last, we compared difference COVID-19 vaccine groups, considering potential confounding factors using univariate multivariate logistic regression. Results Vaccination two three doses was positively associated low prevalence pneumonia severe both crude optimal models, while only correlated death SARS-CoV-2-infected patients. In male individuals advanced age were high pneumonia, death; comorbidity hypertension (OR = 2.532, p < 0.001) 0.001); diabetes 1.856, 0.011). this is cross-sectional study causal relationships need be further studied. Conclusion One dose may not have protective effect against more than one an independent factor for pneumonia; death.

Language: Английский

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Insulin and Metformin Administration: Unravelling the Multifaceted Association with Mortality across Various Clinical Settings Considering Type 2 Diabetes Mellitus and COVID-19

Biomedicines, Journal Year: 2024, Volume and Issue: 12(3), P. 605 - 605

Published: March 7, 2024

Due to the molecular mechanisms of action antidiabetic drugs, they are considered be effective in treatment both COVID-19 and post-COVID-19 syndromes. The aim this study was determine effect administering insulin metformin on mortality patients with type 2 diabetes (T2DM) symptomatic use logistic regression models. association between death weak could not included multivariate model. However, interaction drugs other factors, including remdesivir low-molecular-weight heparin (metformin), age hsCRP (insulin), modulated odds death. These interactions hint at multifaceted (anti-/pro-) associations death, depending patient’s characteristics. In model, RDW-SD, adjusted treatment, age, sex K+, associated among T2DM. With a 15% increase risk increased by 87.7%. This preliminary provides foundations for developing further, more personalized models assess T2DM patients, as well identifying an due COVID-19.

Language: Английский

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The first assessment of Angiotensin-Converting Enzyme 1 (ACE1) D/I polymorphism and demographic factors in association with COVID-19 outcomes in the Moroccan Population

Molecular Biology Reports, Journal Year: 2025, Volume and Issue: 52(1)

Published: Jan. 8, 2025

Language: Английский

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Gender differences in sequelae from COVID-19 infection

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 599 - 613

Published: Jan. 1, 2025

Language: Английский

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The COVID-19 pandemic — what have urologists learned?

Nature Reviews Urology, Journal Year: 2022, Volume and Issue: 19(6), P. 344 - 356

Published: April 13, 2022

Language: Английский

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