Nanoscale sensing based on nitrogen vacancy centers in single crystal diamond and nanodiamonds: achievements and challenges DOI Creative Commons
Mariusz Radtke, Ettore Bernardi, Abdallah Slablab

et al.

Nano Futures, Journal Year: 2019, Volume and Issue: 3(4), P. 042004 - 042004

Published: Dec. 1, 2019

Abstract Powered by the mutual developments in instrumentation, materials and theoretical descriptions, sensing imaging capabilities of quantum emitters solids have significantly increased past two decades. Quantum solids, whose properties resemble those atoms ions, provide alternative ways to probing natural artificial nanoscopic systems with minimum disturbance ultimate spatial resolution. Among emerging emitters, nitrogen vacancy (NV) color center diamond is an outstanding example due its intrinsic at room temperature (highly-luminescent, photo-stable, biocompatible, highly-coherent spin states). This review article summarizes recent advances achievements using NV centers within nano- single crystal diamonds imaging. We also highlight prevalent challenges material aspects for different types outline main parameters consider when as sensors. As a novel resource, we light emitting electrical dipoles their coupling other nanoscale e.g. graphene.

Language: Английский

Research progresses of nanomaterials as lubricant additives DOI Creative Commons
Zhengquan Jiang, Yankun Sun,

Bokang Liu

et al.

Friction, Journal Year: 2024, Volume and Issue: 12(7), P. 1347 - 1391

Published: March 13, 2024

Abstract Friction and wear are unavoidable in mechanical movement. The use of lubricants with nano-additives can effectively reduce friction wear, which is great significance to saving energy protecting the environment. At present, progress has been made scientific research industrial application for lubricants. This paper mainly introduces types (such as carbon nanomaterials, nano-metals, nano-oxides, sulfides, complexes, polymers, etc.), tribological properties different components nano-additives, lubrication mechanisms (including tribofilm formation, rolling ball bearing effect, repairing polishing synergistic effect). It also deals dispersion influences their particle size microstructure on review outlines performance requirements states, discusses challenging working conditions, identifies various oil reference appropriate options diverse environments. Furthermore, existing problems prospects summarized. review, hopefully, would help shed light design synthesis novel high-performance promote engineering.

Language: Английский

Citations

22

Nanodiamonds: Emerging face of future nanotechnology DOI
Sandeep Kumar, Monika Nehra, Deepak Kedia

et al.

Carbon, Journal Year: 2018, Volume and Issue: 143, P. 678 - 699

Published: Nov. 21, 2018

Language: Английский

Citations

152

Sensitive magnetometry in challenging environments DOI Creative Commons
Kai‐Mei C. Fu, Geoffrey Z. Iwata, Arne Wickenbrock

et al.

AVS Quantum Science, Journal Year: 2020, Volume and Issue: 2(4)

Published: Dec. 1, 2020

State-of-the-art magnetic field measurements performed in shielded environments under carefully controlled conditions rarely reflect the realities of those applications envisioned introductions peer-reviewed publications. Nevertheless, significant advances magnetometer sensitivity have been accompanied by serious attempts to bring these magnetometers into challenging working which they are often required. This review discusses ways various (predominantly optically pumped) technologies adapted for use a wide range noisy and physically demanding environments.

Language: Английский

Citations

103

A Perspective on Fluorescent Nanodiamond Bioimaging DOI
Marco D. Torelli, Nicholas Nunn, Olga Shenderova

et al.

Small, Journal Year: 2019, Volume and Issue: 15(48)

Published: June 19, 2019

Abstract The field of fluorescent nanodiamonds (FNDs) has advanced greatly over the past few years. Though historically limited primarily to red fluorescence, wavelengths available for have increased due continuous technical advancement. This Review summarizes strides made in synthesis, functionalization, and application FNDs bioimaging. Highlights range from super‐resolution microscopy, through cellular whole animal imaging, up constantly emerging fields including sensing hyperpolarized magnetic resonance imaging.

Language: Английский

Citations

95

Nanoparticles as delivery vehicles for antiviral therapeutic drugs DOI Creative Commons

Alexander Maus,

Lia Strait,

Donghui Zhu

et al.

Engineered Regeneration, Journal Year: 2021, Volume and Issue: 2, P. 31 - 46

Published: Jan. 1, 2021

With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation pandemics future. Given both wide variety biomaterials at their disposal and recent rise nanotechnology, scientists now have means release distribute therapeutic drugs ways. Such permits medical professionals ability choose methods that would provide best methodologies viral ailment they attempting remedy. This integrative review discusses context previous pandemics, pathogenesis, issues associated with current state antiviral delivery systems, numerous used purpose, further information regarding global pandemic.

Language: Английский

Citations

95

Targeting EGFR of triple-negative breast cancer enhances the therapeutic efficacy of paclitaxel- and cetuximab-conjugated nanodiamond nanocomposite DOI

Wei‐Siang Liao,

Yu Chieh Ho,

Yu-Wei Lin

et al.

Acta Biomaterialia, Journal Year: 2019, Volume and Issue: 86, P. 395 - 405

Published: Jan. 16, 2019

Language: Английский

Citations

94

Nanodiamond Relaxometry-Based Detection of Free-Radical Species When Produced in Chemical Reactions in Biologically Relevant Conditions DOI Creative Commons
Felipe Perona Martínez, Anggrek Citra Nusantara, Mayeul Chipaux

et al.

ACS Sensors, Journal Year: 2020, Volume and Issue: 5(12), P. 3862 - 3869

Published: Dec. 3, 2020

Diamond magnetometry is a quantum sensing method involving detection of magnetic resonances with nanoscale resolution. For instance, T1 relaxation measurements, inspired by equivalent concepts in resonance imaging (MRI), provide signal that to conventional MRI but environment. We use nanodiamonds (between 40 and 120 nm) containing ensembles specific defects called nitrogen vacancy (NV) centers. To perform measurement, we pump the NV center ground state (using laser at 532 observe how long can remain this state. Here, real-time measurements free radicals when they are generated chemical reaction. Specifically, focus on photolysis H2O2 as well so-called Haber–Weiss Both these processes important reactions biological environments. Unlike other fluorescent probes, diamonds able determine spin noise from different species real time. also investigate diamond probes their ability sense gadolinium labels. Although study was performed clean environment, take into account effects salts proteins present conduct our experiments nanodiamonds, which compatible intracellular measurements. between 0 108 nM, reach limits down nanomolar range typically find times few 100 μs. This an step toward label-free nano-MRI quantification

Language: Английский

Citations

89

Recent Progress of Nanocarrier-Based Therapy for Solid Malignancies DOI Open Access

Qi-Yao Wei,

Yan‐Ming Xu, Andy T. Y. Lau

et al.

Cancers, Journal Year: 2020, Volume and Issue: 12(10), P. 2783 - 2783

Published: Sept. 28, 2020

Conventional chemotherapy is still an important option of cancer treatment, but it has poor cell selectivity, severe side effects, and drug resistance. Utilizing nanoparticles (NPs) to improve the therapeutic effect chemotherapeutic drugs been highlighted in recent years. Nanotechnology dramatically changed face oncology by high loading capacity, less toxicity, targeted delivery drugs, increased uptake target sites, optimized pharmacokinetic patterns traditional drugs. At present, research being envisaged field novel nano-pharmaceutical design, such as liposome, polymer NPs, bio-NPs, inorganic so make effective long-lasting. Till now, a number studies have conducted using wide range nanocarriers for treatment solid tumors including lung, breast, pancreas, brain, liver. To provide reference further application chemodrug-loaded nanoformulations, this review gives overview development nanocarriers, updated status their use several tumors.

Language: Английский

Citations

83

Approved and marketed nanoparticles for disease targeting and applications in COVID-19 DOI Creative Commons
Ahmed A. H. Abdellatif, Abdullah Fahad Alsowinea

Nanotechnology Reviews, Journal Year: 2021, Volume and Issue: 10(1), P. 1941 - 1977

Published: Jan. 1, 2021

Abstract Nano-based systems can be used to transport active medicinal products specific parts of the body. Most challenges with drug delivery, such as low water solubility and poor bioavailability, solved using nanotechnology. In addition, nanoparticles overcome various physiological obstacles increase load distribution desired sites. Nanoparticles carry a medication or therapeutic agent, DNA-related substance, enhance time deliver target site in either nonspecific (through enhanced permeability retention (EPR)) binding receptors) manner. Moreover, nanoparticle delivery have been employed clinic since early 1990s. Since then, field nanomedicine has developed growing technical needs improve medications. Over these past decades, newer generations emerged that are capable conducting new activities could enable therapy via innovative modalities. This review highlights different types approved currently marketed nanoparticles, nanocrystals, liposomes, lipid PEGylated polymeric protein-based metal-based nanoparticles. Furthermore, it explores use vaccine-loaded for COVID-19 prophylaxis.

Language: Английский

Citations

74

Quantum Sensing of Free Radicals in Primary Human Dendritic Cells DOI Creative Commons
Linyan Nie, Anggrek Citra Nusantara,

Viraj G. Damle

et al.

Nano Letters, Journal Year: 2021, Volume and Issue: 22(4), P. 1818 - 1825

Published: Dec. 20, 2021

Free radicals are crucial indicators for stress and appear in all kinds of pathogenic conditions, including cancer, cardiovascular diseases, infection. However, they difficult to detect due their reactivity low abundance. We use relaxometry the detection with subcellular resolution. This method is based on a fluorescent defect diamond, which changes its optical properties basis magnetic surroundings. technique allows nanoscale MRI unprecedented sensitivity spatial Recently, this was used inside living cells from cell line. Cell lines differ terms endocytic capability radical production primary derived patients. Here we provide first measurements phagocytic by NADPH oxidase (NOX2) dendritic healthy donors. The these differs greatly between investigated response stimulation or inhibition.

Language: Английский

Citations

58