ACS Applied Nano Materials,
Journal Year:
2024,
Volume and Issue:
7(12), P. 14406 - 14418
Published: June 7, 2024
The
therapeutic
efficacy
of
monotherapy
on
tumors
is
often
limited
due
to
the
constraints
tumor
response
conditions,
significantly
impacting
clinical
treatment
outcomes.
In
this
study,
we
design
a
collaborative
nanosystem
(BBSP)
that
combines
photodynamic
therapy
(PDT)
and
photothermal
(PTT).
system
formulated
by
doping
sulfur
ions
modulate
wide
band
gap
BiF3
semiconductor
nanospheres.
introduction
its
combination
with
bismuth
not
only
enhance
light
absorption
but
also
introduce
oxygen
vacancies
local
surface
plasmon
resonance
effect
bismuth.
Compared
BiF3,
reduced
carrier
separation
efficiency
improved.
Under
irradiation
520
nm
laser,
electrons
reduce
in
process
transition
meanwhile
give
energy
O2,
producing
large
number
reactive
species
(ROS).
Simultaneously,
holes
valence
oxidize
glutathione
(GSH),
coordination
ion
GSH
further
depletes
GSH.
RNA
sequencing
results
reveal
downregulation
GPX4
cells,
inducing
ferroptosis.
Additionally,
sulfide
augmented
absorption,
synergizing
heat,
thereby
increasing
oxidative
damage
inhibiting
growth.
BBSP
emerges
as
promising
strategy
for
treatment,
orchestrating
ferroptosis
apoptosis
through
combined
application
PDT
PTT.
Small,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 30, 2024
Novel
inorganic
sonosensitizers
with
excellent
reactive
oxygen
species
(ROS)
generation
activity
and
multifunctionality
are
appealing
in
sonodynamic
therapy
(SDT).
Herein,
amorphous
bismuth
(Bi)-doped
CoFe-layered
double
hydroxide
(a-CoBiFe-LDH)
nanosheets
proposed
via
crystalline-to-amorphous
phase
transformation
strategy
as
a
new
type
of
bifunctional
sonosensitizer,
which
allows
ultrasound
(US)
to
trigger
ROS
for
magnetic
resonance
imaging
(MRI)-guided
SDT.
Importantly,
a-CoBiFe-LDH
exhibit
much
higher
(≈6.9
times)
than
that
traditional
TiO
Journal of Nanobiotechnology,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Sept. 2, 2023
Abstract
Graphdiyne
has
excellent
potential
due
to
its
enzymatic
properties.
Metal-free
sulfur-doped
(S-GDY)
piezoelectric
characteristics,
and
ultrasonic
excitation
of
S-GDY
enhances
peroxidase
activity.
It
can
turn
hydrogen
peroxide
into
toxic
hydroxyl
radicals
induce
apoptosis
in
4T1
cells.
More
importantly,
the
ultrasound
(US)
enhanced
nanozyme
induced
cell
ferroptosis
by
promoting
an
imbalanced
redox
reaction
glutathione
depletion
4
inactivation.
exhibited
activity
vitro
vivo
that
may
directly
trigger
apoptosis-ferroptosis
for
effective
tumor
therapy.
Altogether,
this
study
was
expected
provide
new
insights
design
catalytic
expand
their
application
therapy
tumors.
Graphical
Tuning
the
charge
transfer
processes
through
a
built-in
electric
field
is
an
effective
way
to
accelerate
dynamics
of
electro-
and
photocatalytic
reactions.
However,
coupling
p–n
heterojunctions
microstrain-induced
polarization
on
impact
piezocatalysis
has
not
been
fully
explored.
Herein,
we
demonstrate
role
p-type
BiOI/n-type
BiVO4
in
enhancing
their
piezocatalytic
behaviors.
The
highly
crystalline
heterojunction
synthesized
by
using
coprecipitation
method
under
ambient
aqueous
conditions.
Under
ultrasonic
irradiation
water
exposed
air,
exhibit
significantly
higher
production
rates
reactive
species
(·OH,
·O2–,
1O2)
as
compared
isolated
BiOI.
Also,
rate
H2O2
with
BiOI/BiVO4
reaches
480
μmol
g–1
h–1,
which
1.6-
12-fold
than
those
BiOI,
respectively.
Furthermore,
maintains
stable
for
up
5
h.
results
from
experiments
equation-driven
simulations
strain
piezoelectric
potential
distributions
indicate
that
reactivity
resulted
intensity
induced
periodic
ultrasound,
enhanced
heterojunctions.
This
study
provides
new
insights
into
design
piezocatalysts
opens
prospects
applications
medicine,
environmental
remediation,
sonochemical
sensors.
ACS Applied Nano Materials,
Journal Year:
2024,
Volume and Issue:
7(12), P. 14406 - 14418
Published: June 7, 2024
The
therapeutic
efficacy
of
monotherapy
on
tumors
is
often
limited
due
to
the
constraints
tumor
response
conditions,
significantly
impacting
clinical
treatment
outcomes.
In
this
study,
we
design
a
collaborative
nanosystem
(BBSP)
that
combines
photodynamic
therapy
(PDT)
and
photothermal
(PTT).
system
formulated
by
doping
sulfur
ions
modulate
wide
band
gap
BiF3
semiconductor
nanospheres.
introduction
its
combination
with
bismuth
not
only
enhance
light
absorption
but
also
introduce
oxygen
vacancies
local
surface
plasmon
resonance
effect
bismuth.
Compared
BiF3,
reduced
carrier
separation
efficiency
improved.
Under
irradiation
520
nm
laser,
electrons
reduce
in
process
transition
meanwhile
give
energy
O2,
producing
large
number
reactive
species
(ROS).
Simultaneously,
holes
valence
oxidize
glutathione
(GSH),
coordination
ion
GSH
further
depletes
GSH.
RNA
sequencing
results
reveal
downregulation
GPX4
cells,
inducing
ferroptosis.
Additionally,
sulfide
augmented
absorption,
synergizing
heat,
thereby
increasing
oxidative
damage
inhibiting
growth.
BBSP
emerges
as
promising
strategy
for
treatment,
orchestrating
ferroptosis
apoptosis
through
combined
application
PDT
PTT.
