Implantable Sensors for Post‐Surgical Monitoring of Vascular Complications DOI Creative Commons

Binfan Zhao,

Loy Eid,

Yuguang Zhang

et al.

Advanced Sensor Research, Journal Year: 2023, Volume and Issue: 2(11)

Published: May 16, 2023

Abstract For surgeries involving vessel anastomosis, it is critical to ensure fluent blood flow and monitor the occurrence of vascular complications. However, current clinical methods are ineffective in achieving direct, continuous, accurate monitoring. At present, implantable sensors widely used explored various biomedical applications, including cardiovascular disease, neurological disorders, cancer treatment, health They can be easily placed during surgical procedures offer irreplaceable advantages directness, continuity, higher accuracy Based on this, types for monitoring reviewed, some preclinical research advances which expected provide promising post‐surgical complications discussed. In end, future perspectives put forward. It believed that hold great promise translation, providing physicians with more accurate, real‐time results, helping improve success patient outcomes.

Language: Английский

Bench-to-bedside: Translational development landscape of biotechnology in healthcare DOI Creative Commons
Caizhi Liao,

Shadow Xiao,

Xia Wang

et al.

Health Sciences Review, Journal Year: 2023, Volume and Issue: 7, P. 100097 - 100097

Published: May 16, 2023

Biotechnology is a rapidly evolving field that has the potential to transform way we diagnose and treat diseases changing landscape of healthcare. Great endeavors have been devoted healthcare biotechnology, our knowledge subject remarkably improved. By leveraging latest advancements in molecular biology genetics, new biotech paradigms are emerging, sparking searches for novel solutions human health well-being. However, clinical translational development breakthrough biotechnology discoveries remains an intriguing challenge. Only few innovations progressed transformative tools therapies. In this review, will outline Notable developments including classical paradigms, thoroughly discussed. Even though great challenges remain bench-to-bedside process, more groundbreaking ideas about be translated into commercial products bring positive gains, with tight multitude collaboration among research institutes, providers, industry partners.

Language: Английский

Citations

37

Salivary analysis: An emerging paradigm for non‐invasive healthcare diagnosis and monitoring DOI Creative Commons
Caizhi Liao, Xiaofeng Chen, Ying Fu

et al.

Deleted Journal, Journal Year: 2023, Volume and Issue: 1(3)

Published: June 2, 2023

Abstract As an emerging non‐invasive and easy‐to‐use toolkit, salivary analysis has garnered significant attention recently. By leveraging the latest discoveries in biomarkers, potential to revolutionize field of healthcare by providing valuable information for monitoring individual's health status, diagnosing disease progression, enabling personalized treatment. However, transitional development breakthrough remains intriguing challenge. Only a few innovations have progressed new transformative diagnosis tools. In this review, we attempt illustrate bird's eye view exploring assorted selection seminar progress that can potentially shape developing trajectory analysis. The fundamental nature saliva versatile robust uses as novel method various diagnostic fields will be thoroughly discussed. To inspire next‐stage thriving fruitful field, also crystalize key findings, pinpoint challenges remain addressed present outlook on future analysis, invigorating research groundbreaking strategies, beyond.

Language: Английский

Citations

32

Paper-based colorimetric sensors for point-of-care testing DOI

Anthony Ko,

Caizhi Liao

Analytical Methods, Journal Year: 2023, Volume and Issue: 15(35), P. 4377 - 4404

Published: Jan. 1, 2023

The versatile uses of paper-based colorimetric sensors in POCT, include infectious disease diagnosis, chronic management, cancer diagnosis and monitoring, pregnancy fertility testing.

Language: Английский

Citations

28

Hedyotis diffusa injection modulates the ferroptosis in bladder cancer via CAV1/JUN/VEGFA DOI
Kaiping Bai,

Yanxi Long,

Fei Yuan

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 147, P. 113925 - 113925

Published: Jan. 7, 2025

Language: Английский

Citations

1

Advancements in Nanomedicine for the Diagnosis and Treatment of Kidney Stones DOI Creative Commons
Wang Yong-qi,

Junyi Yang,

Yirixiatijiang Amier

et al.

International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 1401 - 1423

Published: Feb. 1, 2025

Abstract: Kidney stones constitute a common condition impacting the urinary system. In clinical diagnosis and management, traditional surgical interventions pharmacological treatments are primarily utilized; however, these methods possess inherent limitations. Presently, field of nanomedicine is undergoing significant advancements. The application nanomaterials in biosensors enables accurate assessment ion composition. Furthermore, contrast agents developed from materials can improve signal-to-noise ratio enhance image clarity. By mitigating oxidative stress-induced cellular damage, inhibit formation kidney efficacy drug delivery as effective carriers. Additionally, by modifying physical chemical properties bacteria, effectively eliminate bacterial presence, thereby preventing severe complications. This review explores advancements technology related to early detection risk factors, diagnosis, treatment their associated Keywords: nanomaterials, stones, stress, biomaterial

Language: Английский

Citations

1

Microfluidic-based isolation of circulating tumor cells with high-efficiency and high-purity DOI
Feng Wu,

Xuemin Kong,

Yixuan Liu

et al.

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: 35(8), P. 109754 - 109754

Published: March 11, 2024

Language: Английский

Citations

7

Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring DOI Creative Commons

Anthony Ko,

Caizhi Liao

Hybrid Advances, Journal Year: 2023, Volume and Issue: 3, P. 100052 - 100052

Published: June 9, 2023

Diabetes, a chronic, metabolic disease characterized by elevated levels of blood glucose, over time leads to serious damage the vessels, nerves, eyes, kidneys, and heart. Diabetes affects 422 million people globally, with majority residing in low- middle-income nations, approximately 1.5 deaths are directly attributed diabetes annually. Thus, detecting early is crucial prevent, monitor, or postpone advancement its associated complications. However, current glucose tests for diabetic patients have significant drawback that these methods require frequent intrusive sampling. Promisingly, salivary analysis has emerged as non-invasive convenient alternative monitoring approach diabetics. In this review, we attempt chart landscape emerging field analysis. It not our intention wholly review all related work, but rather an assorted selection seminar reports exemplify development trajectory burgeoning measurement (SGM). The fundamental advantageous nature SGM novel method diagnostic fields will be thematically thoroughly discussed. To inspire next-stage clinical transitional fruitful field, then explicate challenges remain addressed, present future directions

Language: Английский

Citations

16

Polymeric nanoparticles approach and identification and characterization of novel biomarkers for colon cancer DOI Creative Commons
Devesh U. Kapoor, Rahul Garg,

Mansi Gaur

et al.

Results in Chemistry, Journal Year: 2023, Volume and Issue: 6, P. 101167 - 101167

Published: Oct. 14, 2023

The need for novel approaches to the treatment of colon cancer, a common and deadly disease, is universal. In this compilation, we look at how polymeric nanoparticles (Polymeric nanoparticles) could be used treat cancer. Advantages Polymeric in Fig.hting disease include targeted medication administration, enhanced therapy efficacy, fewer adverse effects. Their impact on cancer huge. Drug release miRNA play crucial roles struggle by enabling early identification, individualised strategies, bolstering PONP mechanisms. most up-to-date developments use biomarkers diagnosis prognosis are also discussed. Biomarkers toxicology range from genes epigenomes molecules. Better patient outcomes can expected when conjunction with personalised cytotoxicity assessment. This strategy has potential completely transform care putting needs each first. Combining therapeutic diagnostic capabilities inside single nanoparticle system, drug delivery elevates concept theranostic applications employing method enables toxicological visualise monitor tailored administration. Additional research clinical validation necessary implement these practise. There reason optimistic about future standard medical care.

Language: Английский

Citations

16

Designing a Simple Electrochemical Genosensor for the Detection of Urinary PCA3, a Prostate Cancer Biomarker DOI Creative Commons

Meriem Mokni,

Amal Tlili,

Yassine Khalij

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(5), P. 602 - 602

Published: April 29, 2024

This study investigates the feasibility of a simple electrochemical detection Prostate Cancer Antigen 3 (PCA3) fragments extracted from patients’ urine, using thiolated single-strand DNA probe immobilized on gold surface without redox probe. To enhance PCA3 recognition process, we conducted comparative analysis hybridization location two probes: Probe 1 targets first 40 bases, while 2 fragment bases 47 to 86. Hybridization with followed, square wave voltammetry. The limit designed genosenors were order (2.2 ng/mL), and (1.6 ng/mL) for Probes 2, respectively, subsequent sensitivities (0.09 ± 0.01) µA−1 · µg−1 mL (0.10 mL. Specificity tests then sensor functionalized as it presents better analytical performances. results indicate that can clearly discriminate complementary target non-complementary one. A further modeling calibration curves Power Law/Hill model indicates dissociation constant increases by one magnitude, confirming ability perfectly ones.

Language: Английский

Citations

4

Research trends on nanomaterials in triple negative breast cancer (TNBC): a bibliometric analysis from 2010 to 2024 DOI
Hongyi Liang,

Guoliang Yin,

Dandan Feng

et al.

Drug Delivery and Translational Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 6, 2024

Language: Английский

Citations

4