Aggregate,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 10, 2024
Abstract
Nerve
guidance
conduits
have
demonstrated
great
promise
for
the
restoration
of
injured
peripheral
nerves
in
recent
decades.
Associated
research
has
focused
on
improving
structure
and
function
these
as
well
simplifying
manufacturing
processes.
Herein,
a
novel
decellularized
umbilical
cord
(DUC)
wrapped
with
conductive
hydrogel
is
presented
nerve
regeneration,
which
prepared
by
integrating
DUC
matrix
into
methacrylate
gelatin
(GelMA)/Ti
3
C
2
T
x
MXene
(MXene)
composite
hollow
conduit
(named
DUC–MXene–GelMA
conduit).
The
obtained
displays
superior
mechanical
properties,
electrical
conductivity,
biocompatibility.
Particularly,
ascribed
to
introduction
MXene,
exhibits
satisfactory
biological
effects
promoting
neuron
growth
Schwann
cell
proliferation
migration.
Through
vivo
experiments
using
rat
sciatic
injury
model,
beneficial
axonal
regeneration
motor
recovery
are
demonstrated.
These
findings
indicate
that
may
be
promising
candidate
repair.
Pharmaceuticals,
Journal Year:
2025,
Volume and Issue:
18(1), P. 58 - 58
Published: Jan. 7, 2025
Chronic
wounds
present
a
substantial
healthcare
obstacle,
marked
by
an
extended
healing
period
that
can
persist
for
weeks,
months,
or
even
years.
Typically,
they
do
not
progress
through
the
usual
phases
of
healing,
which
include
hemostasis,
inflammation,
proliferation,
and
remodeling,
within
expected
timeframe.
Therefore,
to
address
socioeconomic
burden
in
taking
care
chronic
wounds,
hydrogel-based
therapeutic
materials
have
been
proposed.
Hydrogels
are
hydrophilic
polymer
networks
with
3D
structure
allows
them
become
skin
substitutes
wounds.
Knowing
peptides
abundant
human
body
possess
distinct
biological
functionality,
activity,
selectivity,
their
adaptability
as
peptide-based
hydrogels
individual
requirements
has
made
significant
potential
biomaterial
treatment
Peptide-based
excellent
physicochemical
mechanical
characteristics
such
biodegradability
swelling,
suitable
rheological
properties
well
great
biocompatibility.
Moreover,
interact
cells,
promoting
adhesion,
migration,
proliferation.
These
cellular
interactions
driven
be
applied
wound
healing.
Gels,
Journal Year:
2024,
Volume and Issue:
10(4), P. 280 - 280
Published: April 21, 2024
Novel
hyaluronic
acid
(HA)
crosslinked
with
pentaerythritol
tetra-acrylate
(PT)
injectable
hydrogels
was
invented.
These
hydrogel/dermal
filler
formulations
were
synthesised
using
HA
and
the
acrylate
PT
as
a
crosslinker
under
basic
pH
conditions
thermal
crosslinking
methods
(oven
heating),
which
provides
simple,
safe,
eco-friendly
method
for
in
4
h
45
°C.
Fourier-transform
infrared
spectroscopy
(FTIR)
scanning
electron
microscopy
(SEM)
analyses
conducted
to
represent
difference
between
terms
of
peak
formation
pore
size,
respectively.
The
partial
is
considered
be
typical
dermal
fillers.
rheological
properties
these
showed
that
novel
injectables
are
highly
promising,
newly
developed
fillers
could
used
better
results
anti-wrinkle
corrections,
shaping,
volumising
reasons.
Furthermore,
residual
analysis
carried
out
state
valid
acceptable
intradermal
usage.
from
GC
validation
revealed
it
suitable
this
study.
all
five
hydrogel/filler
demonstrated
HA-PT
1,
2,
3
formulated
(0.05–0.1)%
w/w
containing
monomers
within
safe
limits
determined
below
(0.008%
w/w).
This
work
has
shown
development
formulation
pharmaceutical
cosmetic
applications
can
prepared
more
sustainable
simple
way
agent,
holds
great
promise
industry’s
future
advancement.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: Aug. 6, 2024
PVA
hydrogels
present
many
characteristics
of
the
ideal
dressing,
although
without
antimicrobial
properties.
The
work
aims
to
study
physical,
mechanical
and
release
hydrogel
wound
dressings
loaded
with
either
two
natural
herbal
products,
sage
extract
dragon's
blood.
Aggregate,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 10, 2024
Abstract
Nerve
guidance
conduits
have
demonstrated
great
promise
for
the
restoration
of
injured
peripheral
nerves
in
recent
decades.
Associated
research
has
focused
on
improving
structure
and
function
these
as
well
simplifying
manufacturing
processes.
Herein,
a
novel
decellularized
umbilical
cord
(DUC)
wrapped
with
conductive
hydrogel
is
presented
nerve
regeneration,
which
prepared
by
integrating
DUC
matrix
into
methacrylate
gelatin
(GelMA)/Ti
3
C
2
T
x
MXene
(MXene)
composite
hollow
conduit
(named
DUC–MXene–GelMA
conduit).
The
obtained
displays
superior
mechanical
properties,
electrical
conductivity,
biocompatibility.
Particularly,
ascribed
to
introduction
MXene,
exhibits
satisfactory
biological
effects
promoting
neuron
growth
Schwann
cell
proliferation
migration.
Through
vivo
experiments
using
rat
sciatic
injury
model,
beneficial
axonal
regeneration
motor
recovery
are
demonstrated.
These
findings
indicate
that
may
be
promising
candidate
repair.
