Responsive Hydrogels Based on Triggered Click Reactions for Liver Cancer DOI

Jiaqi Zhu,

Han Wu,

Zhen‐Li Li

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 34(38)

Published: May 18, 2022

Abstract Globally, liver cancer, which is one of the major cancers worldwide, has attracted growing attention technological researchers for its high mortality and limited treatment options. Hydrogels are soft 3D network materials containing a large number hydrophilic monomers. By adding moieties such as nitrobenzyl groups to structure cross‐linked nanocomposite hydrogel, click reaction improves drug‐release efficiency in vivo, survival rate prolongs time cancer patients. The application hydrogel drug delivery system can not only enrich concentration at tumor site long but also effectively prevents distant metastasis residual cells. At present, researches have been working toward construction responsive systems, there few comprehensive articles systematically summarize these discoveries. Here, this systematic review summarizes synthesis methods related applications hydrogels with actions external or internal physiological stimuli. With different physical chemical stimuli, structural unit rearrangement controlled release drugs be used states.

Language: Английский

Carbon dots: mysterious past, vibrant present, and expansive future DOI
Boyang Wang, Geoffrey I. N. Waterhouse, Siyu Lu

et al.

Trends in Chemistry, Journal Year: 2022, Volume and Issue: 5(1), P. 76 - 87

Published: Nov. 10, 2022

Language: Английский

Citations

161
Zero-Dimensional Carbon Nanomaterials for Fluorescent Sensing and Imaging DOI
Zheng Yang, Tiantian Xu, Hui Li

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(18), P. 11047 - 11136

Published: Sept. 7, 2023

Advances in nanotechnology and nanomaterials have attracted considerable interest play key roles scientific innovations diverse fields. In particular, increased attention has been focused on carbon-based exhibiting extended structures unique properties. Among these materials, zero-dimensional structures, including fullerenes, carbon nano-onions, nanodiamonds, dots, possess excellent bioaffinities superior fluorescence properties that make suitable for application to environmental biological sensing, imaging, therapeutics. This review provides a systematic overview of the classification structural properties, design principles preparation methods, optical sensing applications nanomaterials. Recent interesting breakthroughs sensitive selective imaging heavy metal pollutants, hazardous substances, bioactive molecules as well information encryption, super-resolution photoacoustic phototherapy nanomedicine delivery are main focus this review. Finally, future challenges prospects materials highlighted envisaged. presents comprehensive basis directions designing, developing, applying fascinating fluorescent sensors fabricated based specific requirements numerous research

Language: Английский

Citations

114
Aggregation in carbon dots DOI Creative Commons

Yi Ru,

Geoffrey I. N. Waterhouse, Siyu Lu

et al.

Aggregate, Journal Year: 2022, Volume and Issue: 3(6)

Published: Nov. 21, 2022

Abstract Carbon dots (CDs) possess outstanding luminescence properties, making them widely used in optical displays, anti‐counterfeiting systems, bioimaging, and sensors. Presently, there is much debate about the classification of CDs, as well their formation process, structure, fluorescence mechanisms. Aggregation plays an important role (e.g., aggregation‐induced emission) yet seldom studied detail. This review aims fill this knowledge gap, by first exploring how aggregation leads to different types CDs graphene quantum dots, carbon carbonized polymer dots), followed a detailed examination effect morphology on properties application CDs. Finally, opportunities challenges for various applications are discussed, with need better mechanistic understanding being imperative.

Language: Английский

Citations

111
Rational synthesis of silane-functionalized carbon dots with high-efficiency full-color solid-state fluorescence for light emitting diodes DOI
Guangzhou Hu, Yang Wang, Shuang Zhang

et al.

Carbon, Journal Year: 2022, Volume and Issue: 203, P. 1 - 10

Published: Nov. 20, 2022

Language: Английский

Citations

89
Multiple Stimuli‐Response Polychromatic Carbon Dots for Advanced Information Encryption and Safety DOI

Youfusheng Wu,

Xiao Chen, Wei Wu

et al.

Small, Journal Year: 2023, Volume and Issue: 19(10)

Published: Jan. 15, 2023

Abstract Optical information encryption and safety have aroused great attention since they are closely correlated to data protection safety. The development of multiple stimuli‐response optical materials for constructing large‐capacity is very important practical applications. Carbon dots (CDs) many gratifying merits, such as polychromatic emission, diverse luminous categories, stable physicochemical properties, considered one the most ideal candidates protection. Herein, carbon core, functional groups, solvents, other crucial factors reviewed outputting emission categories. In particular, substrate engineering strategies been emphasized their critical role in yielding excellent features High‐capacity by relying on rich properties CDs, categories fluorescence, afterglow, upconversion, well external‐stimuli‐assisted changes. Some perspectives preparing CDs further developing security proposed. This review provides a good reference manipulation next‐generation

Language: Английский

Citations

71
Antibacterial Carbon Dots‐Based Composites DOI Open Access
Shan Huang,

Yuexin Song,

Jianrong Zhang

et al.

Small, Journal Year: 2023, Volume and Issue: 19(31)

Published: Feb. 17, 2023

Abstract The emergence and global spread of bacterial resistance to conventionally used antibiotics have highlighted the urgent need for new antimicrobial agents that might replace antibiotics. Currently, nanomaterials hold considerable promise as in anti‐inflammatory therapy. Due their distinctive functional physicochemical characteristics exceptional biocompatibility, carbon dots (CDs)‐based composites attracted a lot attention context these nanomaterials. Here, thorough assessment current developments field CDs‐based is provided, starting with brief explanation general synthesis procedures, categorization, composites. many processes driving antibacterial action are then thoroughly described, including physical destruction, oxidative stress, incorporation agents. Finally, obstacles now suffer combating infectious diseases outlined investigated, along potential applications

Language: Английский

Citations

71
Polymer–Structure‐Induced Room‐Temperature Phosphorescence of Carbon Dot Materials DOI Creative Commons
Chengyu Zheng,

Songyuan Tao,

Bai Yang

et al.

Small Structures, Journal Year: 2023, Volume and Issue: 4(5)

Published: Feb. 2, 2023

As emerging carbon‐based nanomaterials, carbon dots (CDs) are widely studied with regard to their luminescent properties. CDs obtained by the bottom‐up method exhibit polymeric characteristics after crosslinking, polymerization, and incomplete carbonization processes, herein referred as carbonized polymer (CPDs). In recent years, large progress has been achieved on room‐temperature phosphorescence (RTP) properties of CPDs. The developments synthesis strategies for RTP CPD materials reviewed. However, less attention devoted influence structures materials. Polymer a common feature extensive key factors facilitating Herein, effects emission self‐protective matrix‐assisted discussed. It is considered that can effectively immobilize subluminophores protect triplet excited states facilitate crosslink‐enhanced (CEE) effect proposed further explain materials, which provide an effective strategy Benefiting from CEE effect, efficient be applications then briefly summarized.

Language: Английский

Citations

60
Red emissive carbon dots as a fluorescent sensor for fast specific monitoring and imaging of polarity in living cells DOI Creative Commons
Zheng Yang, Hui Li, Tiantian Xu

et al.

Journal of Materials Chemistry A, Journal Year: 2023, Volume and Issue: 11(6), P. 2679 - 2689

Published: Jan. 1, 2023

This work presents red emissive CDs as a promising fluorescent sensor with excellent photostability, high fluorescence quantum yield, and negligible cytotoxicity for real-time sensing visualizing polarity changes in mitochondria lysosomes.

Language: Английский

Citations

56
Exploiting machine learning for controlled synthesis of carbon dots-based corrosion inhibitors DOI

Haijie He,

E Shuang,

Li Ai

et al.

Journal of Cleaner Production, Journal Year: 2023, Volume and Issue: 419, P. 138210 - 138210

Published: July 22, 2023

Language: Английский

Citations

56
Carbon quantum dots in bioimaging and biomedicines DOI Creative Commons

Surya Shekhar Das,

Somnath Mondal, Dhiman Ghosh

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 22, 2024

Carbon quantum dots (CQDs) are gaining a lot more attention than traditional semiconductor owing to their intrinsic fluorescence property, chemical inertness, biocompatibility, non-toxicity, and simple inexpensive synthetic route of preparation. These properties allow CQDs be utilized for broad range applications in various fields scientific research including biomedical sciences, particularly bioimaging biomedicines. promising choice advanced nanomaterials biomedicines unique chemical, physical, optical properties. doped with hetero atom, or polymer composite materials extremely advantageous biochemical, biological, since they easy prepare, biocompatible, have beneficial This type CQD is highly useful phototherapy, gene therapy, medication delivery, bioimaging. review explores the biomedicine, highlighting recent advancements future possibilities increase interest numerous advantages therapeutic applications.

Language: Английский

Citations

51