Ultrastable in-situ silver nanoparticle dressing for effective prevention and treatment of wound infection in emergency DOI Creative Commons
Wei Wang, Ziwei Hu,

Wanying Mo

et al.

Engineered Regeneration, Journal Year: 2024, Volume and Issue: 5(1), P. 111 - 123

Published: Jan. 14, 2024

The use of antibacterial dressings is crucial in the prevention and treatment wound infection emergency situations. However, efficacy compromised by long-term storage or exposure to harsh conditions. Here, an ultrastable in-situ silver nanoparticle dressing (AgSNP@CD) was prepared for effective emergency. fabrication process AgSNP@CD simple, suitable large-scale production. Due strong interaction between synthesized AgNPs cotton fabric, owned remarkable stability, thus retaining its antimicrobial even after (up 2 years) under extreme conditions (damp heat, low temperatures, low-oxygen, water immersion, acid-alkali erosion). Both vitro vivo results demonstrated extraordinary stability AgSNP@CD, facilitating healing In particular, exhibited a superior effect on severe bacteria-infected trauma can prevent occurrence sepsis effectively. exceptional complex make it well-suited strategy

Language: Английский

GHK-Cu/Pionin-loaded in situ electrospun PVB/PVP smart dressing promotes wound healing via anti-oxidant, anti-inflammatory, antimicrobial, and tissue regenerative effects DOI
Yan Wang, Zhichao Zheng, Janak L. Pathak

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 492, P. 152154 - 152154

Published: May 14, 2024

Language: Английский

Citations

11

Advancements of Porphyrin‐Derived Nanomaterials for Antibacterial Photodynamic Therapy and Biofilm Eradication DOI Open Access
Suwen Chen,

Baoxuan Huang,

Jia Tian

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(27)

Published: July 27, 2024

Abstract The threat posed by antibiotic‐resistant bacteria and the challenge of biofilm formation has highlighted inadequacies conventional antibacterial therapies, leading to increased interest in photodynamic therapy (aPDT) recent years. This approach offers advantages such as minimal invasiveness, low systemic toxicity, notable effectiveness against drug‐resistant bacterial strains. Porphyrins their derivatives, known for high molar extinction coefficients singlet oxygen quantum yields, have emerged crucial photosensitizers aPDT. However, practical application is hindered challenges poor water solubility aggregation‐induced quenching. To address these limitations, extensive research focused on development porphyrin‐based nanomaterials aPDT, enhancing efficacy sterilization broadening range antimicrobial activity. review provides an overview various utilized aPDT eradication years, including porphyrin‐loaded inorganic nanoparticles, polymer assemblies, supramolecular metal–organic frameworks (MOFs), covalent organic (COFs). Additionally, insights into prospects offered, highlighting its potential implementation.

Language: Английский

Citations

11

Recent Progress in Biomedical Scaffold Fabricated via Electrospinning: Design, Fabrication and Tissue Engineering Application DOI
Feng Cheng, Danyang Song, Hongbin Li

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 26, 2024

Abstract Electrospinning is a significant manufacturing strategy to create micro/nanofiber platforms that can be considered biomedical scaffold for tissue engineering repair and regeneration. In recent years researchers have continuously broadened the equipment design materials development of electrospinning nanofiber (ENPs), which evolved from single‐needle multi‐needle creating 3D ENPs, diversify their application including drugs/cell/growth factors release, anti‐bacterial anti‐inflammatory, hemostasis, wound healing, Herein, multifunctional ENPs with bioactive polymer fabricated via in terms novel material design, construction various structures, requirements different regeneration are reviewed. Furthermore, this review delves into advancements facilitated by highlighting effectiveness versatility across types such as bone, cartilage, tendons, cardiac tissue, nerves. The discussion comprehensively addresses ongoing challenges selection, biodegradation mechanisms, bioactivation strategies, techniques specific applications. Moreover, outlines potential future research avenues aimed at enhancing ENPs‐based approaches engineering. This in‐depth analysis aims provide nuanced insights technical recommendations propel field forward

Language: Английский

Citations

11

Expanding Our Horizons: AIE Materials in Bacterial Research DOI
Michelle M. S. Lee, Eric Y. Yu,

Joe H. C. Chau

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 9, 2024

Abstract Bacteria share a longstanding and complex relationship with humans, playing role in protecting gut health sustaining the ecosystem to cause infectious diseases antibiotic resistance. Luminogenic materials that aggregation‐induced emission (AIE) characteristics have emerged as versatile toolbox for bacterial studies through fluorescence visualization. Numerous research efforts highlight superiority of AIE this field. Recent advances are categorized into four areas: understanding interactions, antibacterial strategies, diverse applications, synergistic applications bacteria. Initial focuses on visualizing unseen bacteria progresses developing strategies involving electrostatic amphiphilic luminogens (AIEgens), various enhance affinity. progress includes using photodynamic photothermal therapies, toxicity studies, combined therapies. Diverse from environmental disinfection disease treatment, utilizing coatings, sensors, wound healing materials, etc., also provided. Finally, combining achieve enhanced outcomes explored. This review summarizes developmental trend is expected provide future directions advancing methodologies.

Language: Английский

Citations

10

Ultrastable in-situ silver nanoparticle dressing for effective prevention and treatment of wound infection in emergency DOI Creative Commons
Wei Wang, Ziwei Hu,

Wanying Mo

et al.

Engineered Regeneration, Journal Year: 2024, Volume and Issue: 5(1), P. 111 - 123

Published: Jan. 14, 2024

The use of antibacterial dressings is crucial in the prevention and treatment wound infection emergency situations. However, efficacy compromised by long-term storage or exposure to harsh conditions. Here, an ultrastable in-situ silver nanoparticle dressing (AgSNP@CD) was prepared for effective emergency. fabrication process AgSNP@CD simple, suitable large-scale production. Due strong interaction between synthesized AgNPs cotton fabric, owned remarkable stability, thus retaining its antimicrobial even after (up 2 years) under extreme conditions (damp heat, low temperatures, low-oxygen, water immersion, acid-alkali erosion). Both vitro vivo results demonstrated extraordinary stability AgSNP@CD, facilitating healing In particular, exhibited a superior effect on severe bacteria-infected trauma can prevent occurrence sepsis effectively. exceptional complex make it well-suited strategy

Language: Английский

Citations

9